Efficacy News and Research

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A new lipid-based nasal ointment effective at reducing symptoms of allergic rhinitis

One in five Americans have allergic rhinitis, a number that is steadily rising, but the exact reasons for this increase are unknown. A new lipid-based nasal ointment is found effective at reducing symptoms of allergic rhinitis in German patients.

18 Sep 2004

Researchers find palatal implants provide effective snoring relief

Researchers find that inserting three matchstick sized pieces of polyester material in the upper palate is a simple, low cost, and easily tolerated office procedure that provides effective snoring relief.

17 Sep 2004

Inhaled nitrite spray may help babies diagnosed with persistent pulmonary hypertension of the newborn

Scientists from the National Institutes of Health (NIH) Clinical Center and the Loma Linda University School of Medicine have found that use of an inhaled nitrite spray may help babies diagnosed with persistent pulmonary hypertension of the newborn (PPHN).

13 Sep 2004

New treatment for T-cell acute lymphoblastic leukaemia

IL-7, a hormone-like protein involved in cell-cell interaction, has been associated with increased survival and expansion of T-cell acute lymphoblastic leukaemia (T-ALL).

9 Sep 2004

Exubera shows sustained blood glucose control in patients with type 2 diabetes

New data showed that Exubera (inhaled insulin) was effective and well tolerated in controlling blood glucose levels over a two-year period in patients with Type 2 diabetes.

8 Sep 2004

The drug galantamine has been shown to be ineffective in treating chronic fatigue syndrome

The drug galantamine (used for treatment of mild to moderate dementia) did not demonstrate a clinical benefit in treating chronic fatigue syndrome when compared with placebo, according to a study in the September 8 issue of JAMA.

8 Sep 2004

FDA approval for chewable ADHD tablets

Alliant Pharmaceuticals has announced FDA approval of Methylin Chewable Tablets and Methylin Oral Solution for the treatment of ADHD. The two products are the first, and only, chewable tablet and oral solution for ADHD to gain FDA acceptance.

7 Sep 2004

Ezetrol co-administration with statin therapy lowers LDL cholesterol in diabetics

Results from two new clinical trials show that patients with diabetes and metabolic syndrome who are treated with ezetimibe (EZETROL®) co-administered with a statin experience greater reductions in LDL (“bad”) cholesterol, compared to patients taking a statin alone.

7 Sep 2004

Generic tritherapy can be used as a basic treatment for AIDS

A clinical trial, conducted in Cameroon by IRD researchers working with other organizations and supported by the ANRS, has demonstrated that one of the most common combinations currently deployed in Africa, using nevirapine, stavudine and lamivudine, satisfies these criteria.

5 Sep 2004

First Parkinson’s gene therapy patient well after 1 year suggesting that the therapy is safe and effective

The first ever patient to have undergone gene therapy for Parkinson’s appears to have come through phase I without a hitch, suggesting that the therapy is safe and effective, reports Marina Murphy in Chemistry & Industry.

2 Sep 2004

Benefit of using clot-busting drug tissue plasminogen activator (tPA) for ischemic stroke

An independent review of data from a landmark clinical trial has validated the benefit of using the clot-busting drug tissue plasminogen activator (tPA) for ischemic stroke, when given within three hours of symptom onset under a strict treatment protocol.

2 Sep 2004

Does the popular Atkins diet really work?

Since it’s introduction in the middle 1970’s, the Atkins Protein Diet has grown to be one of the most popular methods of weight loss. Low-carbohydrate, high-protein diets have been criticized by major health organizations including the American Heart Association, the American Dietetic Association, and the American Kidney Fund.

2 Sep 2004

Hormone leptin could play a key role in treating bone loss, anorexia and infertility in women

A new study has found that the hormone leptin plays a key role in women’s reproductive and neuroendocrine health and suggests a future for the hormone in treating a number of conditions including exercise-induced bone loss, anorexia and in some cases of infertility.

2 Sep 2004

Proven clinical efficiency key to success of nascent European bone graft substitutes market

Increased orthopaedic surgical procedures and an ageing baby boomer generation have been boosting the demand for bone grafts. Even as new applications and innovative products create exciting growth opportunities, the key challenge for bone graft substitutes suppliers is to produce material with clinical efficacy equivalent to, or surpassing, existing alternatives.

2 Sep 2004

More women and adolescents needed in HIV vaccine clinical trials

Greater participation of women and adolescents is needed in HIV vaccine clinical trials, according to a group of international experts, who attended a consultation on HIV vaccine trials in Lausanne, Switzerland, from 26-28 August.

1 Sep 2004

Study suggests that patients with pulmonary arterial hypertension may benefit from Thelin therapy

Encysive Pharmaceuticals today announced the presentation of data from a clinical study of Thelin(TM) (sitaxsentan) in pulmonary arterial hypertension (PAH), at the European Society of Cardiology Annual Congress in Munich.

31 Aug 2004

Ageing population and technological progress combine to drive European orthopaedic braces and supports market

By 2020, the elderly are expected to comprise almost a quarter of Europe's total population. This changing demography is set to underpin a rise in the incidence of age-related orthopaedic problems

31 Aug 2004

Major trends in AIDS research that the different research teams throughout the world are pursuing

The science will be presented during the conference which is taking place in Lausanne until September 1, 2004. The advances in fundamental research, notably through a better understanding of the complex processes of immune defence, HIV and the functioning of vaccines, promote the genesis and development of new vaccine candidates.

30 Aug 2004

New study confirms benefits of rimonabant in weight loss

Phase III clinical study comparing placebo to rimonabant, the first agent in a new therapeutic class known as selective cannabinoid type 1 (CB1) blockers, showed that overweight or obese people taking rimonabant 20mg once daily benefited from a significant reduction in their body weight

29 Aug 2004

Dronedarone is effective and well-tolerated in the prevention of atrial fibrillation

New anti-arrhythmic agent, dronedarone, is highly effective in the prevention of atrial fibrillation or atrial flutter recurrence, serious disorders of cardiac rhythm, and is well-tolerated by patients.

29 Aug 2004

Efficacy News and Research

A new lipid-based nasal ointment effective at reducing symptoms of allergic rhinitis

Researchers find palatal implants provide effective snoring relief

Inhaled nitrite spray may help babies diagnosed with persistent pulmonary hypertension of the newborn

New treatment for T-cell acute lymphoblastic leukaemia

Exubera shows sustained blood glucose control in patients with type 2 diabetes

The drug galantamine has been shown to be ineffective in treating chronic fatigue syndrome

FDA approval for chewable ADHD tablets

Ezetrol co-administration with statin therapy lowers LDL cholesterol in diabetics

Generic tritherapy can be used as a basic treatment for AIDS

First Parkinson’s gene therapy patient well after 1 year suggesting that the therapy is safe and effective

Benefit of using clot-busting drug tissue plasminogen activator (tPA) for ischemic stroke

Does the popular Atkins diet really work?

Hormone leptin could play a key role in treating bone loss, anorexia and infertility in women

Proven clinical efficiency key to success of nascent European bone graft substitutes market

More women and adolescents needed in HIV vaccine clinical trials

Study suggests that patients with pulmonary arterial hypertension may benefit from Thelin therapy

Ageing population and technological progress combine to drive European orthopaedic braces and supports market

Major trends in AIDS research that the different research teams throughout the world are pursuing

New study confirms benefits of rimonabant in weight loss

Dronedarone is effective and well-tolerated in the prevention of atrial fibrillation

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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