Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

Sequencing the Asian liver fluke genome: an interview with Dr Neil Young

Opisthorchis viverrini is a parasitic flatworm (or liver fluke) endemic throughout Thailand, the Lao People’s Democratic Republic, Vietnam and Cambodia. Humans are infected with this parasite when they eat a fluke encysted in inadequately cooked/preserved freshwater fish.

21 Sep 2014

Curie-Cancer, Inventiva launch Epicure project that aims to develop epigenetic targets for cancer

Curie-Cancer, the body responsible for developing Institut Curie’s industry partnership activities, and Inventiva, a drug discovery company that focuses on therapeutic approaches involving transcription factors and epigenetic targets, today announce the launch of the Epicure project, which has just received financial backing from France’s national research agency, the ANR [Agence Nationale pour la Recherche].

17 Sep 2014

New ACD European subsidiary aims to provide faster, enhanced support for local customers

Advanced Cell Diagnostics Inc., a technology and market leader in the field of molecular pathology and developer of cell and tissue-based analysis tools, has announced the establishment of a European subsidiary which will start business in October 2014.

From Advanced Cell Diagnostics 16 Sep 2014

Hudson Robotics awarded NIH grant to develop HTS system for in vivo studies of zebrafish

Hudson Robotics, Inc., of Springfield, NJ, in cooperation with Johns Hopkins University, has recently been awarded an NIH grant to develop a commercially viable high-throughput screening (HTS) system for in vivo studies of zebrafish.

15 Sep 2014

Six research institutions awarded NIH grants to create database of human cellular responses

Building on a successful three-year pilot project, the National Institutes of Health has awarded more than $64 million to six research institutions to create a database of human cellular responses, the Library of Integrated Network-based Cellular Signatures.

15 Sep 2014

BGI-VPC Joint Research Laboratory to apply genome research to develop new cancer therapies

BGI, the world’s largest genomics organization, based in China, and The Vancouver Prostate Centre, a global leader in translational research in cancer, today announced the establishment of the BGI-VPC Joint Research Laboratory, a sequencing and translational research facility, to jointly discover and advance basic and translational programs in oncology, including personalized oncology.

15 Sep 2014

Fogarty receives three grants for research focused on biodiversity conservation

In addition to diseases for which there are ineffective or no cures, key pathogens are becoming increasingly drug-resistant.

10 Sep 2014

Professor Bill Charman awarded FIP Lifetime Achievement Award in Pharmaceutical Sciences

The International Pharmaceutical Federation has honoured a prominent Monash scientist and Dean for his outstanding contribution to pharmaceutical sciences.

5 Sep 2014

Chromatin immunoprecipitation informative brochure published by Porvair Sciences

Porvair Sciences has published an informative 8-page brochure providing scientists with a background to Chromatin Immunoprecipitation (ChIP), an introduction to Chromatrap® ChIP assay technology and how Chromatrap® compares to traditional bead based methodologies.

From Chromatrap® - Porvair Sciences Ltd 4 Sep 2014

Using iPS technology researchers develop new therapies for Parkinson's disease and ALS

Dresden. Dr. Jared Sterneckert is entering the research area "Neurodegenerative Diseases" of the DFG Research Center and Cluster of Excellence at the TU Dresden as a new junior group leader. Since 2006, he has led a team working at the "Max Planck Institute for Molecular Biomedicine" in Münster to develop models of Parkinson's disease and amyotrophic lateral sclerosis.

3 Sep 2014

Wockhardt receives coveted QIDP status from FDA for WCK 771 and WCK 2349 drugs

Wockhardt Limited today announces a major boost to the New Drug Discovery program in Anti-Infective research when two of its drugs, WCK 771 and WCK 2349, received the coveted Qualified Infectious Disease Product (QIDP) status from U.S. Food & Drug Administration.

1 Sep 2014

NEOMED gets $12 million to support academic researchers on drug development

NEOMED, a not-for-profit organization whose mission is to create a bridge between academic research and the pharmaceutical industry, will receive $12 million in funding from the Government of Canada to help academic researchers turn their early discoveries into future medicines.

26 Aug 2014

UC Santa Cruz cancer researcher receives $350,000 to develop novel drugs for breast cancer

UC Santa Cruz cancer researcher Seth Rubin has received a $350,000 grant to fund his work toward the development of a new class of drugs for treating breast cancer. The grant is a Breast Cancer Research Program Breakthrough Award from the congressionally directed medical research programs of the U.S. Department of Defense.

19 Aug 2014

BioTek continues to set the standard in microplate instrumentation

BioTek continues to set the standard in microplate instrumentation by designing practical functionality, user-friendly software, and affordable modularity as seen in the new Synergy™ HTX Multi-Mode Microplate Reader. This new system is offered as an entry-level multi-mode reader to automate UV-Vis absorbance, fluorescence, luminescence and AlphaScreen®/AlphaLISA® assays in 6- to 384-well microplates in 2 µL samples with BioTek’s Take3 Micro-Volume plates.

15 Aug 2014

Leica Biosystems, ACD co-market RNAscope LS ISH assays and BOND RX instrument

Leica Biosystems and Advanced Cell Diagnostics, Inc. (ACD) have announced the co-marketing of ACD's RNAscope® LS ISH assays with Leica Biosystems' BOND RX research staining platform.

From Advanced Cell Diagnostics 13 Aug 2014

Cancer Research UK, CRT and Astellas collaborate to find new drug targets for pancreatic cancer

Cancer Research UK and its commercial arm, Cancer Research Technology (“CRT”), are to join forces with Astellas Pharma Inc. (Tokyo, President & CEO: Yoshihiko Hatanaka, “Astellas”) to find new drug targets in the fight against cancer, with an initial focus on pancreatic cancer.

8 Aug 2014

Engineers create truly portable device for nuclear magnetic resonance spectroscopy

A team of engineers at the Harvard School of Engineering and Applied Sciences (SEAS), Schlumberger-Doll Research Center in Cambridge, Mass., and the University of Texas, Austin, have created a truly portable device for nuclear magnetic resonance (NMR) spectroscopy.

5 Aug 2014

Cloud Pharmaceuticals awarded Phase I grant from NSF SBIR program

Cloud Pharmaceuticals, Inc., a therapeutics company focused on cloud-based drug design and development, announced today that it has been awarded a Phase I grant from the National Science Foundation Small Business Innovation Research program.

29 Jul 2014

Biochemists report advance in production of functional mirror-image proteins

University of Utah biochemists have reported an advance in the production of functional mirror-image proteins.

29 Jul 2014

Xybion to host first annual Global User Group Conference in Philadelphia, Pennsylvania

Xybion Corporation, the leading provider of software, services and consulting for global corporations operating in highly regulated industries, announced today that the company will host its first annual Global User Group Conference, Xybion International Exchange, on October 21-23, 2014 in historic Philadelphia, Pennsylvania at the Sheraton Society Hill Hotel.

26 Jul 2014

Drug Discovery News and Research

Further Reading

Sequencing the Asian liver fluke genome: an interview with Dr Neil Young

Curie-Cancer, Inventiva launch Epicure project that aims to develop epigenetic targets for cancer

New ACD European subsidiary aims to provide faster, enhanced support for local customers

Hudson Robotics awarded NIH grant to develop HTS system for in vivo studies of zebrafish

Six research institutions awarded NIH grants to create database of human cellular responses

BGI-VPC Joint Research Laboratory to apply genome research to develop new cancer therapies

Fogarty receives three grants for research focused on biodiversity conservation

Professor Bill Charman awarded FIP Lifetime Achievement Award in Pharmaceutical Sciences

Chromatin immunoprecipitation informative brochure published by Porvair Sciences

Using iPS technology researchers develop new therapies for Parkinson's disease and ALS

Wockhardt receives coveted QIDP status from FDA for WCK 771 and WCK 2349 drugs

NEOMED gets $12 million to support academic researchers on drug development

UC Santa Cruz cancer researcher receives $350,000 to develop novel drugs for breast cancer

BioTek continues to set the standard in microplate instrumentation

Leica Biosystems, ACD co-market RNAscope LS ISH assays and BOND RX instrument

Cancer Research UK, CRT and Astellas collaborate to find new drug targets for pancreatic cancer

Engineers create truly portable device for nuclear magnetic resonance spectroscopy

Cloud Pharmaceuticals awarded Phase I grant from NSF SBIR program

Biochemists report advance in production of functional mirror-image proteins

Xybion to host first annual Global User Group Conference in Philadelphia, Pennsylvania

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