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Researchers show how diesel fumes could potentially worsen underlying respiratory conditions

Scientists have shown how diesel fumes trigger respiratory reflexes which could potentially worsen underlying conditions, such as asthma.

22 May 2017

Study identifies two T cell biomarkers that may predict survival trajectory of IPF patients

Two T cell biomarkers appear to predict the survival trajectory of patients with idiopathic pulmonary fibrosis (IPF), a lung disease that has a varied, but ultimately devastating, impact on patients, according to new research presented at the ATS 2017 International Conference.

22 May 2017

Study: Angiotensin II can safely improve blood pressure among critically ill patients with hypotension

Sixty years after Cleveland Clinic researchers first isolated the role of angiotensin II in controlling blood pressure, a new international study led by Cleveland Clinic researchers shows that the compound can safely improve blood pressure among critically ill patients who are experiencing life-threatening hypotension, or low blood pressure.

22 May 2017

Researchers discover innovative way to produce hematopoietic stem cells

A study published on May 17 in Nature, discovers an innovative method to produce infinite supply of healthy blood cells from the readily available cells that line blood vessels. This achievement by the researchers at Weill Cornell Medicine marks the first time that any research group has generated such blood-forming stem cells.

18 May 2017

Researchers explore new treatment combination for pediatric patients with Hodgkin lymphoma

Pediatric and young adult patients whose Hodgkin lymphoma has recurred or is resistant to initial treatment can achieve remission and even cure with secondary treatments.

18 May 2017

Study highlights need to monitor transplant donor and recipient for identifying M. hominis infection

The way in which heart and lung transplant recipients acquired a specific species of bacteria, Mycoplasma hominis, had been previously undefined, and the bacterium was difficult to test.

16 May 2017

New IsoPSA assay detects prostate cancer more precisely than current tests

A team of researchers from Cleveland Clinic, Louis Stokes Cleveland VA Medical Center, Kaiser Permanente Northwest, and other clinical sites have demonstrated that a new blood test known as IsoPSA detects prostate cancer more precisely than current tests in two crucial measures - distinguishing cancer from benign conditions, and identifying patients with high-risk disease.

15 May 2017

Study finds no clear benefit of stem-cell transplant for double-hit lymphoma patients in remission

Patients with double hit lymphoma (DHL) who undergo autologous stem-cell transplantation (autoSCT) after achieving remission are not more likely to remain in remission or live longer than patients who do not undergo autoSCT, according to a new analysis from the Perelman School of Medicine and the Abramson Cancer Center of the University of Pennsylvania.

15 May 2017

Study provides insights into how HCMV infection causes birth defects

Fresh insights into how a common virus replicates could pave the way for new therapies to stop its spread.

15 May 2017

CUMC researchers create new organoids that mimic features of full-sized lung

New lung "organoids"-tiny 3-D structures that mimic features of a full-sized lung- have been created from human pluripotent stem cells by researchers at Columbia University Medical Center. The team used the organoids to generate models of human lung diseases in a lab dish, which could be used to advance our understanding of a variety of respiratory diseases.

11 May 2017

Cancer screening for transplant patients do not meet existing guidelines, new study finds

People who have received organ transplants are at higher risk of developing and dying of cancer than the general population. Yet their rates of cancer screening do not meet existing guidelines, a new study has found.

9 May 2017

Individuals who follow healthy lifestyle less likely to have colorectal cancer risk, survey finds

A Cleveland Clinic colon cancer risk assessment survey found that respondents who exercised more followed a healthy diet and did not smoke were less likely to have a personal history of colorectal cancer or colon polyps.

8 May 2017

Secondhand smoke may have different effects on men and women, Amish community research finds

New research at the University of Maryland School of Medicine has found that secondhand smoke tends to have somewhat different effects on men and women.

5 May 2017

New technique improves accuracy, reduces costs of real-time assessment of kidney function

A new technique developed by researchers at Lawrence Livermore National Lab promises to improve accuracy and lower costs of real-time assessment of kidney function, reports an article published this week by SPIE, the international society for optics and photonics, in the Journal of Biomedical Optics.

5 May 2017

Scientists grow and purify earliest lung progenitors from human stem cells

Human lungs, like all organs, begin their existence as clumps of undifferentiated stem cells. But in a matter of months, the cells get organized. They gather together, branch and bud, some forming airways and others alveoli, the delicate sacs where our bodies exchange oxygen for carbon dioxide.

3 May 2017

New treatment offers hope for kidney failure and transplant patients with rare disorder

A novel treatment offers kidney failure and kidney transplant patients with a rare disorder new hope. The treatment allows targeted elimination of plasma cell clones producing abnormal proteins that deposits in the kidneys and leads to kidney failure, according to new research.

3 May 2017

Liver transplant patients who take new anti-rejection drug gain less weight, study finds

Researchers have discovered that a new anti-rejection drug that is gentler on the kidneys after liver transplant also reduces weight gain, which is common after surgery and can lead to serious complications for transplant patients.

3 May 2017

Novel strategy may improve survival of grafts, outcomes in high-risk corneal transplant patients

Treating donor corneas with a cocktail of molecules prior to transplanting to a host may improve survival of grafts and, thus, outcomes in high-risk corneal transplant patients, according to a new study led by researchers at Massachusetts Eye and Ear.

2 May 2017

Study shows safety, efficacy of endoscopic needle knife therapy for intestinal strictures in IBD patients

Cleveland Clinic doctors have published the first study illustrating the safety and efficacy of endoscopic needle knife therapy for intestinal strictures in patients with inflammatory bowel disorder.

28 Apr 2017

Researchers develop risk calculator to estimate chances of kidney failure in living donors

Researchers have developed a risk calculator to provide personalized risk estimates of developing kidney failure after donation.

28 Apr 2017

Transplant News and Research

Researchers show how diesel fumes could potentially worsen underlying respiratory conditions

Study identifies two T cell biomarkers that may predict survival trajectory of IPF patients

Study: Angiotensin II can safely improve blood pressure among critically ill patients with hypotension

Researchers discover innovative way to produce hematopoietic stem cells

Researchers explore new treatment combination for pediatric patients with Hodgkin lymphoma

Study highlights need to monitor transplant donor and recipient for identifying M. hominis infection

New IsoPSA assay detects prostate cancer more precisely than current tests

Study finds no clear benefit of stem-cell transplant for double-hit lymphoma patients in remission

Study provides insights into how HCMV infection causes birth defects

CUMC researchers create new organoids that mimic features of full-sized lung

Cancer screening for transplant patients do not meet existing guidelines, new study finds

Individuals who follow healthy lifestyle less likely to have colorectal cancer risk, survey finds

Secondhand smoke may have different effects on men and women, Amish community research finds

New technique improves accuracy, reduces costs of real-time assessment of kidney function

Scientists grow and purify earliest lung progenitors from human stem cells

New treatment offers hope for kidney failure and transplant patients with rare disorder

Liver transplant patients who take new anti-rejection drug gain less weight, study finds

Novel strategy may improve survival of grafts, outcomes in high-risk corneal transplant patients

Study shows safety, efficacy of endoscopic needle knife therapy for intestinal strictures in IBD patients

Researchers develop risk calculator to estimate chances of kidney failure in living donors

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

Automating research - solutions and best practices

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