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Combination of NSAIDs and TNF inhibitors linked to reduced radiographic progression in AS patients

Celecoxib combined with TNF inhibitors was associated with the greatest reduction in radiographic progression.

14 Jun 2018

Alnylam announces new positive results from Phase 1/2 study of lumasiran in patients with PH1

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today new positive results from its Phase 1/2 study with lumasiran, an investigational RNAi therapeutic targeting glycolate oxidase for the treatment of Primary Hyperoxaluria Type 1.

8 Jun 2018

Study finds factors that help or hinder patient involvement in clinical trials of mitochondrial disease

As clinical trials gear up with the aim of attaining the first FDA-approved treatments for mitochondrial disease, a new study reports for the first time what patients and families say would motivate them for or against participating in such research trials.

7 Jun 2018

FDA approves first oral medication for adults with moderately to severely active ulcerative colitis

The U.S. Food and Drug Administration today expanded the approval of Xeljanz (tofacitinib) to include adults with moderately to severely active ulcerative colitis. Xeljanz is the first oral medication approved for chronic use in this indication.

30 May 2018

New trial to test if omega-3 capsules can stop secondary liver cancer recurrence after surgery

A new clinical trial from the University of Leeds is testing omega-3 capsules in patients who have bowel cancer which has spread to the liver, to see if it can stop the cancer returning after surgery.

30 May 2018

Growth hormone shows potential to completely transform treatment for stroke survivors

Less fatigue and better recovery of cognitive abilities such as learning and memory. These may be the results of growth hormone treatment after a stroke, an experimental study of mice published in the journal Stroke suggests.

30 May 2018

FDA approves novel enzyme therapy for adults with rare and serious genetic disease

The U.S. Food and Drug Administration today approved Palynziq (pegvaliase-pqpz) for adults with a rare and serious genetic disease known as phenylketonuria (PKU).

25 May 2018

Bath geriatrician leads new UK-wide trial into Parkinson’s disease

It will test whether a commonly prescribed dementia drug could prevent debilitating falls for people with the disease. Falls are a frequent complication of Parkinson's, which affect around 60 percent of the 127,000-people diagnosed with the condition each year.

24 May 2018

Study explores brain chemistry of alcohol exposure in people with family history of AUD

People with a family history of alcohol use disorder release more dopamine in the brain's main reward center in response to the expectation of alcohol than people diagnosed with the disorder, or healthy people without any family history of AUD, reports a new study in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.

23 May 2018

Researchers find new method to treat severe asthma

Researchers from McMaster University and the Firestone Institute for Respiratory Health at St. Joseph's Healthcare Hamilton, together with colleagues at other partnering institutions, have developed a new method to treat severe asthma.

23 May 2018

Celgene to share new and updated data around novel hematological therapies

Celgene Corporation today announced that data from a broad range of early and late stage studies evaluating Celgene investigational agents and investigational uses of marketed products will be presented at the 23rd European Hematology Association annual meeting in Stockholm, Sweden, from June 14-17, 2018.

22 May 2018

Investigational drug offers hope of relief for celiac disease patients exposed to gluten

An investigational new drug offers hope of relief for celiac disease patients who are inadvertently exposed to gluten while on a gluten-free diet.

22 May 2018

Pfizer starts Phase 1/2 study of RSV vaccine candidate in healthy adult volunteers

Pfizer Inc. today announced that it has started a Phase 1/2 trial of its respiratory syncytial virus (RSV) vaccine candidate in healthy adult volunteers. RSV is a common respiratory virus that affects the lungs and airways, with significant impact on young children and older adults.

22 May 2018

Ingesting blue dye tablet during colonoscopy aids in detecting difficult-to-see polyps

Ingestion of a blue dye tablet during bowel prep for colonoscopy could be a significant advance in the early detection of colorectal cancer.

22 May 2018

Vitamin C consumption may reduce harm to baby's lungs due to smoking during pregnancy

Women who are unable to quit smoking during their pregnancy may reduce the harm smoking does to their baby's lungs by taking vitamin C, according to a new randomized, controlled trial presented at the ATS 2018 International Conference.

22 May 2018

Eczema drug alleviates asthma symptoms and improves lung function

Two new studies of patients with difficult-to-control asthma show that the eczema drug dupilumab alleviates asthma symptoms and improves patients' ability to breathe better than standard therapies.

22 May 2018

PSCK9 inhibitors may provide benefit to atherosclerosis patients with high lipoprotein(a) levels

Lipoprotein(a) is a variant of LDL (low-density lipoprotein) cholesterol, and large amounts of data have shown that higher lipoprotein(a) levels are associated with an increased risk of cardiovascular events.

22 May 2018

FDA approves new drug to treat thrombocytopenia in adults with chronic liver disease

The U.S. Food and Drug Administration today approved Doptelet (avatrombopag) tablets to treat low blood platelet count (thrombocytopenia) in adults with chronic liver disease who are scheduled to undergo a medical or dental procedure. This is the first drug approved by the FDA for this use.

22 May 2018

Study: Prediabetic patients with OSA could lower their resting heart rates by using CPAP

Patients with prediabetes who also have obstructive sleep apnea may improve their resting heart rate, an important measure of cardiovascular health, by using continuous positive airway pressure to treat their OSA, according to a randomized, controlled trial presented at the ATS 2018 International Conference.

21 May 2018

Clinical trial begins enrollment to test safety of experimental MERS treatments

Enrollment has begun in an early-stage clinical trial testing the safety of two human monoclonal antibodies (mAbs) designed to treat people infected with Middle East respiratory syndrome coronavirus (MERS-CoV).

18 May 2018

Placebo News and Research

Combination of NSAIDs and TNF inhibitors linked to reduced radiographic progression in AS patients

Alnylam announces new positive results from Phase 1/2 study of lumasiran in patients with PH1

Study finds factors that help or hinder patient involvement in clinical trials of mitochondrial disease

FDA approves first oral medication for adults with moderately to severely active ulcerative colitis

New trial to test if omega-3 capsules can stop secondary liver cancer recurrence after surgery

Growth hormone shows potential to completely transform treatment for stroke survivors

FDA approves novel enzyme therapy for adults with rare and serious genetic disease

Bath geriatrician leads new UK-wide trial into Parkinson’s disease

Study explores brain chemistry of alcohol exposure in people with family history of AUD

Researchers find new method to treat severe asthma

Celgene to share new and updated data around novel hematological therapies

Investigational drug offers hope of relief for celiac disease patients exposed to gluten

Pfizer starts Phase 1/2 study of RSV vaccine candidate in healthy adult volunteers

Ingesting blue dye tablet during colonoscopy aids in detecting difficult-to-see polyps

Vitamin C consumption may reduce harm to baby's lungs due to smoking during pregnancy

Eczema drug alleviates asthma symptoms and improves lung function

PSCK9 inhibitors may provide benefit to atherosclerosis patients with high lipoprotein(a) levels

FDA approves new drug to treat thrombocytopenia in adults with chronic liver disease

Study: Prediabetic patients with OSA could lower their resting heart rates by using CPAP

Clinical trial begins enrollment to test safety of experimental MERS treatments

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