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Food: the good, the bad and the ugly

As a society, we may be more obsessed with food than we've ever been. The alarming levels of obesity along with the rise of clean eating and orthorexia are perhaps just some indicators of the food-obsessed world we live in.

2 Feb 2017

Autologous hematopoietic cell transplant may induce sustained remission of multiple sclerosis

New clinical trial results provide evidence that high-dose immunosuppressive therapy followed by transplantation of a person's own blood-forming stem cells can induce sustained remission of relapsing-remitting multiple sclerosis (MS), an autoimmune disease in which the immune system attacks the central nervous system.

2 Feb 2017

Research provides insight into how melanoma and other cancers spread from solid tumors

In a second human case, a Yale-led research team has found that a melanoma cell and a white blood cell can fuse to form a hybrid with the ability to metastasize. The finding provides further insight into how melanoma and other cancers spread from solid tumors with implications for future treatment.

30 Jan 2017

Orthopaedic research helps nurse recover from knee injury

Working as a bedside nurse requires extensive physical effort — pushing wheelchairs and beds, twisting and lifting, and long periods on your feet.

28 Jan 2017

New computer program helps discover 1000 new mutations in blood group genes

1000 new mutations in the blood group genes: that is what physician and former programmer Mattias Möller found in his research study in which he developed new software and investigated blood group genes in 2504 people.

28 Jan 2017

Intravenous contrast media used in CT not linked to increased risk of acute kidney injury

Intravenous contrast media (typically iohexol or iodixanol) used in computed tomography does not appear to be associated with chronic kidney disease, dialysis, kidney transplant or acute kidney injury, despite long-held fears to the contrary.

27 Jan 2017

Human cells integrated into pig and cow embryos

Scientists have shown for the first time that undifferentiated human stem cells can be integrated into early embryos of both pigs and cattle. The construction of such interspecies embryos may represent an important development in the generation of organs for transplant.

27 Jan 2017

Islets from rat-grown mouse pancreases can help reverse disease in diabetic mice

Mouse pancreases grown in rats generate functional, insulin-producing cells that can reverse diabetes when transplanted into mice with the disease, according to researchers at the Stanford University School of Medicine and the Institute of Medical Science at the University of Tokyo.

25 Jan 2017

Scientists harness rabies viruses for assessing connectivity of nerve cell transplants

Scientists under the leadership of the University of Bonn have harnessed rabies viruses for assessing the connectivity of nerve cell transplants: coupled with a green fluorescent protein, the viruses show where replacement cells engrafted into mouse brains have connected to the host neural network.

19 Jan 2017

High-donor-volume hospitals more likely to have improved OTPD rate than low-volume medical centers

Hospitals that manage the highest volume of deceased organ donors are 52 percent more likely to recover an above-average number of transplantable organs per donor compared with low-volume hospitals, according to results from a new study conducted across three U.S. donation regions.

19 Jan 2017

Soft robotic sleeve that mimics healthy cardiac muscles could aid failing hearts

Every year about 2,100 people receive heart transplants in the United States, while 5.7 million suffer from heart failure. Given the scarcity of available donor hearts, clinicians and biomedical engineers from Boston Children's Hospital and Harvard University have spent several years developing a mechanical alternative.

19 Jan 2017

Researchers uncover new pathway in the body that stimulates liver repair

A team of Michigan State University researchers, led by James Luyendyk in the College of Veterinary Medicine, has uncovered a new pathway in the body that stimulates liver repair.

19 Jan 2017

New review discusses about care for pediatric liver transplant recipients

A new review discusses important consideration when caring for children who have received liver transplants.

18 Jan 2017

Synthesized steroid prevents lethal protein buildup in animal model of Parkinson's disease

A synthesized steroid mirroring one naturally made by the dogfish shark prevents the buildup of a lethal protein implicated in some neurodegenerative diseases, reports an international research team studying an animal model of Parkinson's disease.

17 Jan 2017

Biomarker could help identify heart failure patients suitable for cardiac recovery therapies

Investigators at the University of Utah have identified distinct differences in the hearts of advanced heart failure patients who have defied the odds and showed signs of recovery from the disease. Published online in the journal Circulation, the new findings could help clinicians identify the best candidates for cardiac recovery therapies.

17 Jan 2017

Knowledge bank approach could help find best treatment option for AML patients

An international collaboration led by clinical researchers at the Wellcome Trust Sanger Institute has shown proof-of-concept that truly personalised therapy will be possible in the future for people with cancer.

17 Jan 2017

Researchers discover underlying cause for formation of granulomas

Granulomas are tissue nodules of immune cells that occur in diseases such as tuberculosis and sarcoidosis and can damage many organs.

16 Jan 2017

Novel treatment can effectively inhibit development of GVHD in mice, study shows

Graft-versus-host-disease (GVHD) is the leading cause of non-relapse associated death in patients who receive stem cell transplants.

12 Jan 2017

Genetic testing at UMMC helps doctors identify effective medication for heart stent patients

The University of Maryland Medical Center is now offering a simple genetic test to patients who receive heart stents to determine whether they have a genetic deficiency that affects how they respond to a common drug to prevent blood clots.

12 Jan 2017

Penn State researchers develop novel compound to combat cytomegalovirus

A Retro94-based compound may prevent a common and sometimes fatal virus -- human cytomegalovirus (CMV) -- from reproducing and help to protect immunocompromised patients, such as those with HIV, on chemotherapy, with transplants, and infants from the effects of the disease, according to Penn State College of Medicine researchers.

10 Jan 2017

Transplant News and Research

Food: the good, the bad and the ugly

Autologous hematopoietic cell transplant may induce sustained remission of multiple sclerosis

Research provides insight into how melanoma and other cancers spread from solid tumors

Orthopaedic research helps nurse recover from knee injury

New computer program helps discover 1000 new mutations in blood group genes

Intravenous contrast media used in CT not linked to increased risk of acute kidney injury

Human cells integrated into pig and cow embryos

Islets from rat-grown mouse pancreases can help reverse disease in diabetic mice

Scientists harness rabies viruses for assessing connectivity of nerve cell transplants

High-donor-volume hospitals more likely to have improved OTPD rate than low-volume medical centers

Soft robotic sleeve that mimics healthy cardiac muscles could aid failing hearts

Researchers uncover new pathway in the body that stimulates liver repair

New review discusses about care for pediatric liver transplant recipients

Synthesized steroid prevents lethal protein buildup in animal model of Parkinson's disease

Biomarker could help identify heart failure patients suitable for cardiac recovery therapies

Knowledge bank approach could help find best treatment option for AML patients

Researchers discover underlying cause for formation of granulomas

Novel treatment can effectively inhibit development of GVHD in mice, study shows

Genetic testing at UMMC helps doctors identify effective medication for heart stent patients

Penn State researchers develop novel compound to combat cytomegalovirus

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

Automating research - solutions and best practices

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