Immune System News and Research

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First-of-its-kind platform generates antitumor immunity and improves responses to checkpoint inhibitors

Researchers at The University of Texas MD Anderson Cancer Center have developed an ultrasound-guided cancer immunotherapy platform that generates systemic antitumor immunity and improves the therapeutic efficacy of immune checkpoint blockade.

30 May 2022

Study shows how stress has a major impact on the immune system's ability to fight infections

Acute stress can be detrimental to fighting off infection, especially COVID-19, and increases the chance of dying in mouse models.

30 May 2022

Mapping the Types and Traits of Immune Cells

In this interview, News-Medical speaks to two researchers each discussing their respective studies that have contributed to the Human Cell Atlas; Dr. Chenqu Suo and Dr. Cecilia Domínguez Conde from the Wellcome Sanger Institute.

30 May 2022

Using diffusion-weighted MRI to visualize brain inflammation in vivo for the first time

Research of the laboratories led by Dr. Silvia de Santis and Dr. Santiago Canals, both from the Institute of Neurosciences UMH-CSIC (Alicante, Spain), has made it possible to visualize for the first time and in great detail brain inflammation using diffusion-weighted Magnetic Resonance Imaging.

27 May 2022

T cells can die without rest and maintenance, scientists say

T cells, biology textbooks teach us, are the soldiers of the immune system, constantly on the ready to respond to a variety of threats, from viruses to tumors.

27 May 2022

Researchers identify a gene that plays vital role in the innate human immune system

Cedars-Sinai investigators have identified a gene that plays an essential role in the innate human immune system. The gene, NLRP11, helps activate the inflammatory response that tells the body's white blood cells to go on the attack against a foreign presence.

27 May 2022

SARS-CoV-2 genome analysis could boost disease surveillance

Continued monitoring of the evolution of the virus that causes COVID-19 as the pandemic progresses could strengthen disease surveillance systems and aid preparedness for new variants, a study suggests.

27 May 2022

New therapeutic approach harnesses the body's immune system to protect against brain damage

A therapeutic method for harnessing the body's immune system to protect against brain damage is published today by researchers from the Babraham Institute's Immunology research program.

27 May 2022

New approach could treat brain tumors and also prevent or delay recurrences

Scientists at the University of Michigan Rogel Cancer Center were optimistic when they identified a small molecule that blocked a key pathway in brain tumors.

27 May 2022

Risk factors for COVID-19 in patients with hematological malignancies

Researchers investigate the risk factors present in individuals suffering from hematological malignancies and COVID-19.

26 May 2022

New evidence confirms that enterovirus D68 causes acute flaccid myelitis

A case report published in the New England Journal of Medicine provides evidence that enterovirus D68 directly infects spinal cord neurons and that a corresponding robust immune response is present – a direct causation to the polio-like paralyzing illness, acute flaccid myelitis (AFM).

26 May 2022

Researchers receive $8 million grant to prevent traumatic brain injury in military personnel

Researchers backed by an $8 million U.S. Department of Defense grant will explore how to better prevent traumatic brain injury, or TBI, in military personnel exposed to blast shock waves.

26 May 2022

Novavax missed its global moonshot but is angling to win over mRNA defectors

Novavax hitched its wagon to the global coronavirus pandemic. Before most Americans truly grasped the scope of the danger, the small Maryland biotech startup had secured $1.6 billion in U.S. funding for its covid vaccine. Its moonshot goal: delivering 2 billion shots to the world by mid-2021.

26 May 2022

New initiative aims to increase collaboration and accelerate high-impact cancer immunotherapy

The accelerated advancement of cancer immunology and immunotherapy, a type of biological therapy that boosts the immune system's ability to recognize and kill cancer cells, has significantly improved the effectiveness of cancer treatment and patient outcomes.

25 May 2022

Novel mechanism to turn on cancer-killing T cells identified

Over the past decade, researchers have made great strides in the development and administration of cancer immunotherapies, which use the body's own immune system to treat disease.

25 May 2022

NTU scientists discover why NAFLD patients are at higher risk of cardiovascular disease

Patients with non-alcoholic fatty liver disease (NAFLD) are at higher risk of cardiovascular disease, because NAFLD prompts the over-production of a class of proteins that cause inflammation and damage to their blood vessels.

25 May 2022

The effectiveness of sotrovimab vs. molnupiravir in preventing severe COVID-19 outcomes in non-hospitalized high-risk COVID-19 adult patients

Researchers compared the efficacy of sotrovimab and molnupiravir in preventing severe COVID-19 outcomes among non-hospitalized and high-risk COVID-19 patients across England.

25 May 2022

Association between reactogenicity and immunogenicity in SARS-CoV-2 mRNA-1273 vaccination

A recent study currently under review at Scientific Reports journal and posted to the Research Square* preprint server demonstrated a potential positive correlation between reactogenicity and immunogenicity of coronavirus disease 2019 (COVID-19) vaccination.

25 May 2022

Immunogenicity of BNT162b2 COVID-19 vaccine in melanoma patients receiving immunotherapy

In a recent study under review at the Scientific Reports journal and posted to the Research Square* preprint server, researchers evaluated the efficacy of messenger ribonucleic acid (mRNA)-based coronavirus disease 2019 (COVID-19) vaccine BNT162b2 in cancer patients under treatment with immune checkpoint inhibitors (ICIs).

25 May 2022

Serological biomarker predicts severe Crohn's disease seven years prior to diagnosis

An international team led by a University of Toronto researcher has found that an antibody detectable in blood predicts severe Crohn's disease and is detectable up to seven years prior to disease diagnosis.

24 May 2022

Immune System News and Research

First-of-its-kind platform generates antitumor immunity and improves responses to checkpoint inhibitors

Study shows how stress has a major impact on the immune system's ability to fight infections

Mapping the Types and Traits of Immune Cells

Using diffusion-weighted MRI to visualize brain inflammation in vivo for the first time

T cells can die without rest and maintenance, scientists say

Researchers identify a gene that plays vital role in the innate human immune system

SARS-CoV-2 genome analysis could boost disease surveillance

New therapeutic approach harnesses the body's immune system to protect against brain damage

New approach could treat brain tumors and also prevent or delay recurrences

Risk factors for COVID-19 in patients with hematological malignancies

New evidence confirms that enterovirus D68 causes acute flaccid myelitis

Researchers receive $8 million grant to prevent traumatic brain injury in military personnel

Novavax missed its global moonshot but is angling to win over mRNA defectors

New initiative aims to increase collaboration and accelerate high-impact cancer immunotherapy

Novel mechanism to turn on cancer-killing T cells identified

NTU scientists discover why NAFLD patients are at higher risk of cardiovascular disease

The effectiveness of sotrovimab vs. molnupiravir in preventing severe COVID-19 outcomes in non-hospitalized high-risk COVID-19 adult patients

Association between reactogenicity and immunogenicity in SARS-CoV-2 mRNA-1273 vaccination

Immunogenicity of BNT162b2 COVID-19 vaccine in melanoma patients receiving immunotherapy

Serological biomarker predicts severe Crohn's disease seven years prior to diagnosis

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