Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

AstraZeneca to present Phase III CVOT DECLARE-TIMI 58 results at AHA Scientific Sessions

AstraZeneca will present 20 abstracts including a late-breaking oral presentation on the full results from the Phase III cardiovascular outcomes trial DECLARE -TIMI 58, the broadest SGLT2 inhibitor CVOT conducted to date, as well as new research from the Company's Cardiovascular, Renal & Metabolism therapy area at the American Heart Association Scientific Sessions, November 10-12, 2018, in Chicago, Illinois, USA.

1 Nov 2018

Unraveling a rare genetic mutation related to growth disorders

What would happen if you suddenly stopped growing at age 12 or 13? Solving genetic growth mysteries and scheduling regular appointments with pediatric endocrinologists is atypical for most parents and pediatricians.

1 Nov 2018

NIH funding will allow four pediatric health systems to study causes of growth disorders

The National Institutes of Health awards Andrew Dauber, M.D., MMSc, the chief of endocrinology at Children's National Health System, a five-year grant that will allow four pediatric health systems to compile and study clinical and genetic markers of severe pediatric growth disorders.

31 Oct 2018

Alzheimer's Association's Part the Cloud program funds innovative research on brain cells

Innovative research aimed to possibly rejuvenate brain cells will be explored by six international researchers with the goal of discovering effective drugs for people with early stage Alzheimer's disease and other dementias.

31 Oct 2018

Air pollution kills 600,000 children with India being worst affected says WHO

A report from the World Health Organisation (WHO) says that air pollution is responsible for killing nearly 600,000 children every year. Among millions of other children affected with the effects of air pollution it leads to severe symptoms of various conditions such as asthma, respiratory diseases, loss of intelligence, excessive weight gain and ear infections.

31 Oct 2018

Natural protein may offer novel therapy to reverse disorders associated with metabolic syndrome

To the great surprise of cancer researchers, a protein they investigated for its possible role in cancer turned out to be a powerful regulator of metabolism.

29 Oct 2018

Getting right level of leptin may help protect cardiovascular health

Like that famous bowl of porridge, when leptin levels are "just right" they help protect our cardiovascular health, scientists say.

29 Oct 2018

Gut microbiota can contribute to type 2 diabetes

A study published in the journal Cell shows that the gut microbiota has the ability to affect how cells respond to insulin, and can thus contribute to type 2 diabetes. The findings demonstrate an hereto unknown pathological mechanism.

26 Oct 2018

Gastric sleeve or bypass surgery can prevent womb cancer in obese women

A study of women who had gastric sleeve or bypass surgery for obesity has found that precancerous tissue in their womb reverted to normal tissue when they lost weight.

25 Oct 2018

Treating gum disease could help people with Type 2 diabetes manage their blood glucose levels

A study funded by Diabetes UK has found that treating periodontitis (gum disease) could help people with Type 2 diabetes manage their blood glucose levels, and may reduce their risk of diabetes-related complications.

25 Oct 2018

New $3.3 million grant will fund human cell atlas of type 1 diabetes

The mechanism leading to development of type 1 diabetes remains a mystery, hampering the ability to find new ways to prevent, treat or even cure this condition.

25 Oct 2018

Insulin discovery could improve treatments for diabetes

An international collaboration co-led by researchers at the Walter and Eliza Hall Institute has made a discovery that could make therapeutic insulins more effective by better mimicking the way insulin works in the body.

24 Oct 2018

Research offers clue on how females stay healthier than males, despite eating a high fat diet

New research from York University on fat tissue is providing an important clue as to how females stay healthier than males, even as their body fat increases.

24 Oct 2018

Study examines factors associated with fasting hyperglucagonemia in type 2 diabetes

A new study examined the relationship between fasting hyperglucagonemia -- which can negatively affect glucose metabolism in patients with type 2 diabetes -- and several biochemical and glycemic factors in subjects with T2D or in a nondiabetic control group.

24 Oct 2018

Study uncovers new mechanism of action in a first-line drug for diabetes

For decades, metformin has been the first-line drug in the treatment of type 2 diabetes, lowering blood glucose levels by inhibiting glucose production in the liver. Metformin also improves glucose uptake and use by muscle tissue.

23 Oct 2018

Merck presents MK-1454 Phase 1 data for treatment of advanced solid tumors or lymphomas

Merck, known as MSD outside the United States and Canada, today announced the first presentation of preliminary data from a Phase 1 clinical trial evaluating MK-1454, an investigational STING (stimulator of interferon genes) agonist, as monotherapy and in combination with KEYTRUDA (pembrolizumab), Merck's anti-PD-1 therapy, in patients with advanced solid tumors or lymphomas.

22 Oct 2018

Merck presents KEYNOTE-057 trial results for patients with high-risk non-muscle invasive bladder cancer

Merck, known as MSD outside the United States and Canada, today announced the first presentation of results from an interim analysis of KEYNOTE-057, a Phase 2 trial evaluating KEYTRUDA, Merck's anti-PD-1 therapy, for previously treated patients with high-risk non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ or CIS plus papillary disease (Cohort A).

22 Oct 2018

Takeda announces positive Phase 3 ALTA-1L data in first-line therapy for advanced ALK+ NSCLC

Takeda Pharmaceutical Company Limited today announced that intracranial efficacy data from the Phase 3 ALTA-1L (ALK in Lung Cancer Trial of BrigAtinib in 1st Line) trial showed improved intracranial progression-free survival (PFS) and intracranial objective response rate (ORR) with ALUNBRIG (brigatinib) compared to crizotinib among anaplastic lymphoma kinase-positive (ALK+) non-small cell lung cancer (NSCLC) patients.

22 Oct 2018

A new approach identified to control Zika virus, dengue fever

Mosquitoes are the world's deadliest animals, killing thousands of people and causing millions of illnesses each year.

19 Oct 2018

New pragmatic study launched to understand the effectiveness of new type 2 diabetes drug

HealthCore, Inc., the outcomes research subsidiary of Anthem, Inc. and Novo Nordisk Inc., which manufacturers the once weekly GLP-1 receptor agonist Ozempic (semaglutide), are working together to launch the first of its kind pragmatic study to understand the benefits of semaglutide as compared with all other available diabetes drugs in a real-world pragmatic clinical trial for Type 2 diabetes - one of the nation's fastest growing chronic diseases.

17 Oct 2018

Insulin News and Research

Further Reading

AstraZeneca to present Phase III CVOT DECLARE-TIMI 58 results at AHA Scientific Sessions

Unraveling a rare genetic mutation related to growth disorders

NIH funding will allow four pediatric health systems to study causes of growth disorders

Alzheimer's Association's Part the Cloud program funds innovative research on brain cells

Air pollution kills 600,000 children with India being worst affected says WHO

Natural protein may offer novel therapy to reverse disorders associated with metabolic syndrome

Getting right level of leptin may help protect cardiovascular health

Gut microbiota can contribute to type 2 diabetes

Gastric sleeve or bypass surgery can prevent womb cancer in obese women

Treating gum disease could help people with Type 2 diabetes manage their blood glucose levels

New $3.3 million grant will fund human cell atlas of type 1 diabetes

Insulin discovery could improve treatments for diabetes

Research offers clue on how females stay healthier than males, despite eating a high fat diet

Study examines factors associated with fasting hyperglucagonemia in type 2 diabetes

Study uncovers new mechanism of action in a first-line drug for diabetes

Merck presents MK-1454 Phase 1 data for treatment of advanced solid tumors or lymphomas

Merck presents KEYNOTE-057 trial results for patients with high-risk non-muscle invasive bladder cancer

Takeda announces positive Phase 3 ALTA-1L data in first-line therapy for advanced ALK+ NSCLC

A new approach identified to control Zika virus, dengue fever

New pragmatic study launched to understand the effectiveness of new type 2 diabetes drug

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