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Phase 2 clinical trial is now open at Columbia to test gene therapy for dry macular degeneration

A phase 2 clinical trial is underway at Columbia University and NewYork-Presbyterian to test an investigational gene therapy for dry age-related macular degeneration, a progressive, chronic eye disease with no cure and a leading cause of blindness in the United States.

9 Mar 2021

Somatic gene mutations in brain cells could contribute to schizophrenia pathology

Schizophrenia is a neurodevelopmental disorder that disrupts brain activity producing hallucinations, delusions, and other cognitive disturbances. Researchers have long searched for genetic influences in the disease, but genetic mutations have been identified in only a small fraction--fewer than a quarter--of sequenced patients.

9 Mar 2021

Sugar-sweetened soda intake associated with increased risk of mortality among breast cancer patients

New research from the University at Buffalo suggests that breast cancer patients who drink sugar-sweetened beverages regularly are at increased risk for death from any cause and breast cancer in particular.

9 Mar 2021

Human cerebral organoid model to screen drugs for treatment of Creutzfeldt-Jakob disease

Approximately two years after establishing a human cerebral organoid system to study Creutzfeldt-Jakob disease (CJD), National Institutes of Health researchers have further developed the model to screen drugs for potential CJD treatment.

9 Mar 2021

New brain sensor could transform our understanding of Alzheimer’s

Scientists at the University of Virginia School of Medicine have developed a tool to monitor communications within the brain in a way never before possible, and it has already offered an explanation for why Alzheimer's drugs have limited effectiveness and why patients get much worse after going off of them.

9 Mar 2021

New research project aims to treat patients with secondary brain damage

The Universities of Birmingham and Cambridge have launched a new research project aimed at discovering if selective P2X7 receptor blocker drugs can be repurposed to treat patients with secondary brain damage.

9 Mar 2021

Study: More than 2/3 of Indiana nursing home staff show willingness to receive COVID-19 vaccine

In a study conducted shortly before COVID-19 vaccines became available in the U.S., more than two-thirds of nursing home and assisted living staff in Indiana indicated willingness to receive a vaccine immediately or in the future.

8 Mar 2021

Study offers new clues to how night shift work increases cancer risk

New clues as to why night shift workers are at increased risk of developing certain types of cancer are presented in a new study conducted at Washington State University Health Sciences Spokane.

8 Mar 2021

Radiotherapy-resistant cancers could be rendered susceptible through immunotherapy treatment

Cancers that are resistant to radiotherapy could be rendered susceptible through treatment with immunotherapy, a new study suggests.

8 Mar 2021

Diphtheria is evolving to become antibiotic-resistant and could lead to vaccine escape

Diphtheria - a relatively easily-preventable infection - is evolving to become resistant to a number of classes of antibiotics and in future could lead to vaccine escape, warn an international team of researchers from the UK and India.

8 Mar 2021

In-licensed candidate may be an effective intervention for premature infants with respiratory distress syndrome

The Lundquist Institute (TLI) and The Bill & Melinda Gates Medical Research Institute (Gates MRI) executed a license agreement for TLI intellectual property covering a synthetic lung surfactant formulation to be developed for respiratory distress syndrome (RDS) for premature infants in Low- and Middle-Income countries (LMIC).

8 Mar 2021

A sneak peek of the current state and future use of artificial intelligence in pathology

Artificial intelligence can already scan images of the eye to assess patients for diabetic retinopathy, a leading cause of vision loss, and find evidence of strokes on brain CT scans.

8 Mar 2021

Scientists receive the Brain Prize for groundbreaking contributions to novel migraine therapies

The Brain Prize has been awarded to Michael A. Moskowitz, M.D., a professor of neurology at Harvard Medical School at the Massachusetts General Hospital, Charlestown, who also is supported by an NIH grant.

8 Mar 2021

ACTIV-3 clinical trial evaluating investigational COVID-19 therapies closes enrollment in two sub-studies

The ACTIV-3 clinical trial, which is evaluating the safety and efficacy of investigational therapeutics for COVID-19 in hospitalized patients, has closed enrollment in two sub-studies: one examining the investigational monoclonal antibody therapy VIR-7831, and another evaluating the investigational combination monoclonal antibody therapy containing BRII-196 and BRII-198.

5 Mar 2021

Unstable initiation by young people to working life is linked with poorer mental health

A new study reveals that a precarious, unstable initiation by young people to working life is associated with poorer future mental health.

5 Mar 2021

Researchers develop first wearable device to precisely monitor jaundice in newborns

Researchers in Japan have developed the first wearable devices to precisely monitor jaundice, a yellowing of the skin caused by elevated bilirubin levels in the blood that can cause severe medical conditions in newborns.

4 Mar 2021

Administering zinc supplements to Covid-19 patients may help reduce mortality and recovery time

Administering zinc supplements to Covid-19 patients with low levels of this element may be a strategy to reduce mortality and recovery time.

4 Mar 2021

Coronavirus deranges the immune system in complex and deadly ways

There's a reason soldiers go through basic training before heading into combat: Without careful instruction, green recruits armed with powerful weapons could be as dangerous to one another as to the enemy.

4 Mar 2021

Researchers discover a safe, effective, reversible male contraceptive agent

In a new paper published by Nature Communications, The Lundquist Institute (TLI) Investigator Wei Yan, MD, PhD, and his research colleagues spell out an innovative strategy that has led to the discovery of a natural compound as a safe, effective and reversible male contraceptive agent in pre-clinical animal models

4 Mar 2021

Researchers identify the trigger of key cellular change in amyotrophic lateral sclerosis

Scientists at the Francis Crick Institute and UCL have identified the trigger of a key cellular change in amyotrophic lateral sclerosis (ALS), a type of motor neurons disease.

4 Mar 2021

Medical Research News and Research

Phase 2 clinical trial is now open at Columbia to test gene therapy for dry macular degeneration

Somatic gene mutations in brain cells could contribute to schizophrenia pathology

Sugar-sweetened soda intake associated with increased risk of mortality among breast cancer patients

Human cerebral organoid model to screen drugs for treatment of Creutzfeldt-Jakob disease

New brain sensor could transform our understanding of Alzheimer’s

New research project aims to treat patients with secondary brain damage

Study: More than 2/3 of Indiana nursing home staff show willingness to receive COVID-19 vaccine

Study offers new clues to how night shift work increases cancer risk

Radiotherapy-resistant cancers could be rendered susceptible through immunotherapy treatment

Diphtheria is evolving to become antibiotic-resistant and could lead to vaccine escape

In-licensed candidate may be an effective intervention for premature infants with respiratory distress syndrome

A sneak peek of the current state and future use of artificial intelligence in pathology

Scientists receive the Brain Prize for groundbreaking contributions to novel migraine therapies

ACTIV-3 clinical trial evaluating investigational COVID-19 therapies closes enrollment in two sub-studies

Unstable initiation by young people to working life is linked with poorer mental health

Researchers develop first wearable device to precisely monitor jaundice in newborns

Administering zinc supplements to Covid-19 patients may help reduce mortality and recovery time

Coronavirus deranges the immune system in complex and deadly ways

Researchers discover a safe, effective, reversible male contraceptive agent

Researchers identify the trigger of key cellular change in amyotrophic lateral sclerosis

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