Cerebrovascular Disease News and Research

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Cerebrovascular disease is a group of brain dysfunctions related to disease of the blood vessels supplying the brain. Hypertension is the most important cause; it damages the blood vessel lining, endothelium, exposing the underlying collagen where platelets aggregate to initiate a repairing process which is not always complete and perfect. Sustained hypertension permanently changes the architecture of the blood vessels making them narrow, stiff, deformed, uneven and more vulnerable to fluctuations in blood pressure.

Scientists outline criteria for assessing vascular cognitive impairment in post-mortem brain tissue

New research, led by academics at the University of Bristol, has outlined the first validated set of pathological criteria for assessing the likelihood that cognitive impairment was caused by vascular disease.

7 Sep 2016

CPAP treatment offers no cardiovascular benefit in OSA patients with heart disease risk

More than 3 years of nightly treatment with a continuous positive airway pressure (CPAP) machine did not reduce cardiovascular risk more than usual care among patients with cardiovascular disease and obstructive sleep apnea (OSA).

30 Aug 2016

Maternal placental syndromes increase short-term risk of developing cardiovascular disease

The short-term risk of developing cardiovascular disease following a first pregnancy is higher for women experiencing placental syndromes and a preterm birth or an infant born smaller than the usual size, a University of South Florida study reports.

27 Jul 2016

FDA approves new ExAblate Neuro to treat patients with essential tremor

The U.S. Food and Drug Administration today approved the first focused ultrasound device to treat essential tremor in patients who have not responded to medication. ExAblate Neuro uses magnetic resonance (MR) images taken during the procedure to deliver focused ultrasound to destroy brain tissue in a tiny area thought to be responsible for causing tremors.

11 Jul 2016

Non-drug solutions for postpartum depression: an interview with Dr David Brock & Christopher Thatcher

Postpartum depression (PPD) is reported to occur in 10-15% of delivering women with an estimated 400,000 women affected annually in the US. It is the most common complication of childbirth and is a significant public health concern.

11 Jul 2016

Brain vessel diseases may contribute to Alzheimer's dementia

While strokes are known to increase risk for dementia, much less is known about diseases of large and small blood vessels in the brain, separate from stroke, and how they relate to dementia.

4 Jul 2016

Shift work alters internal body clock and leads to strokes, serious brain implications

Statistics show that some 15 million Americans don't work the typical nine-to-five. These employees (or shift workers), who punch in for graveyard or rotating shifts, are more prone to numerous health hazards, from heart attacks to obesity, and now, new research, published in Endocrinology, shows shift work may also have serious implications for the brain.

2 Jun 2016

Penn researchers discover molecular mechanism that underlies common cerebrovascular disease

Cerebral cavernous malformations (CCMs) are clusters of dilated, thin-walled blood vessels in the brain that can cause stroke and seizures, yet exactly how they form is somewhat of a mystery. Now, a team from the Perelman School of Medicine at the University of Pennsylvania has discovered the molecular mechanism that underlies this common cerebrovascular disease. They published their results this week online ahead of print in Nature.

31 Mar 2016

Orexigen Therapeutics, Valeant Pharmaceuticals sign distribution agreement for Mysimba

Orexigen Therapeutics, Inc. today announced Valeant Pharmaceuticals International, Inc. will commercialize Mysimba (naltrexone HCl / bupropion HCl prolonged release) in Central and Eastern Europe.

15 Mar 2016

Diffusion tensor imaging ‘should be routine’ in SVD assessment

Gait speed and microstructural brain damage may be the best indicators of mortality risk in patients with small vessel disease, say researchers.

4 Feb 2016

Common mortality causes prevail in epilepsy patients

A prospective, community-based study confirms that patients with epilepsy usually die of the same causes as other people.

19 Jan 2016

APOE ε4 predicts risk of future depression

One of the most powerful predictors in neuropsychiatry is the epsilon 4 (ε4) allele of the apolipoprotein gene (APOE).

3 Nov 2015

Very long-term outcomes of childhood onset epilepsy reported

A study in Epilepsia presents seizure remission outcomes as well as detailed clinical and neurological findings from a minimum 45-year follow-up of a Finnish cohort of individuals with childhood-onset epilepsy.

30 Oct 2015

New studies analyse life expectancy, causes of death and child mortality in different regions of China

Two new studies, published in The Lancet, reveal for the first time how health in different regions of China has changed in recent decades.

28 Oct 2015

Localisation of policies crucial to China's health reforms, new studies suggest

Two new studies, published in The Lancet, reveal for the first time how health in different regions of China has changed in recent decades. The articles analyse life expectancy, causes of death, and child mortality for 31 provinces, municipalities, autonomous regions of China, and Hongkong and Macao special administrative regions, finding that in the last two decades, life expectancy has risen, and deaths in children under 5 years have fallen, in every province.

26 Oct 2015

CML arterial adverse events rate dependent on TKI choice

The risk of major arterial adverse events in chronic myeloid leukaemia patients may significantly differ between tyrosine kinase inhibitors, suggests a meta-analysis published in Leukemia & Lymphoma.

22 Oct 2015

Treatment with life-saving medications increases in IHD but levels still suboptimal

Treatment with life-saving medications has increased over the past ten years in ischaemic heart disease but levels are still suboptimal, according to the first results of the Chronic Ischaemic Cardiovascular Disease (CICD) Pilot Registry presented today at ESC Congress 2015 and published in European Heart Journal.

2 Sep 2015

Cerebrovascular Disease News and Research

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