Metabolite News and Research

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Metabolites are the intermediates and products of metabolism. The term ''metabolite'' is usually restricted to small molecules.

Metabolite discovery offers a potential way to address metabolic conditions

"Metabolism" describes the body's chemical changes that create the necessary materials for growth and overall health. Metabolites are the substances made and used during these metabolic processes-;or, as a new discovery out of Scripps Research and its drug development arm, Calibr, indicates, they could also be potent molecules for treating severe diseases.

13 Oct 2022

KAUST research could open new avenues for cancer drug development

Precise details of how a master regulator of gene expression binds its activating partner could open new avenues for cancer drug development.

10 Oct 2022

Study investigates associations between potential endocrine-disrupting chemicals and female fertility

About one in six women of reproductive age face difficulties in conceiving or carrying a pregnancy to term. Although there has been a global increase in the use of assisted reproductive technologies (ARTs), the success rate of live birth has remained almost the same.

3 Oct 2022

Prenatal phthalate exposure associated with reduced lung function during childhood

A study led by the Barcelona Institute for Global Health (ISGlobal), a center supported by the "la Caixa" Foundation, has found that exposure to phthalates in the womb is associated with reduced lung function during childhood.

3 Oct 2022

Brazilian study reveals the effects of SARS-CoV-2 infection on the central nervous system

A Brazilian study published in the journal PNAS describes some of the effects infection by SARS-CoV-2 can have on the central nervous system.

30 Sep 2022

How are diet and exercise in bodybuilders associated with the gut microbiota and metabolites?

A recent study explored the diet-exercise-gut microbiome dynamics in male bodybuilders.

30 Sep 2022

Researchers discover how cancer cells can turn off the immune system to help tumors grow

When cancer arises in the body, it starts with tumor cells that rapidly grow and divide and eventually spread.

29 Sep 2022

Shape-shifting mitochondria influence Th17 cells’ propensity for autoimmune activity

A new study focused on the immune system's Th17 cells suggests that the shape and function of their mitochondria (the powerhouse of cells) is important in autoimmune and inflammatory disorders, such as multiple sclerosis.

28 Sep 2022

Study finds strong links between certain gut bacteria and small molecules in the blood

There are strong links between bacteria living in the gut and the levels of small molecules in the blood known as metabolites.

23 Sep 2022

Study supports the importance of healthy diet for better cognitive function across races, ethnicities

Dietary choices and their consequences may certainly influence cognitive function. A new study led by investigators at Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, along with outside collaborators expands on previously published work (focused on Puerto Rican individuals in the U.S.) by including additional races and ethnicities.

16 Sep 2022

The impact of the infant gut microbiome on vaccine efficacy

A new study reports the effect of the infant gut microbiome on vaccine efficacy.

13 Sep 2022

Role of the transketolase-like 1 gene in the development of the modern human brain

In a new study, researchers demonstrated how transketolase-like 1 (TKTL1) gene expression influenced neocortical neurogenesis in modern humans.

12 Sep 2022

Tumor-derived factors stimulate effector trogocytosis and inhibit CAR T cells

The immune system is equipped to respond not just to external invaders-;think viruses, bacteria, and parasites-;but also to internal threats, namely, cancer. Yet, frequently, malignancies overcome the immune system's defenses and evade detection.

12 Sep 2022

Researchers review role of melatonin in pregnancies complicated by placental insufficiency

A new study explores the role of melatonin in pregnancy.

8 Sep 2022

Recent literature reports on the role of the gut microbiome on human health and its effect on diseases

Researchers assessed the role of the gut microbiome in human health and disease.

8 Sep 2022

Transplanting gut bacteria from donors with sleep apnea can cause cardiovascular changes in mice

Researchers from the University of Missouri School of Medicine and MU Health Care have discovered how obstructive sleep apnea affects the gut microbiome in mice and how transplanting gut bacteria from sleep apnea affected mice can cause cardiovascular changes in the recipient mice.

7 Sep 2022

Metabolite News and Research

Further Reading

Metabolite discovery offers a potential way to address metabolic conditions

KAUST research could open new avenues for cancer drug development

Study investigates associations between potential endocrine-disrupting chemicals and female fertility

Prenatal phthalate exposure associated with reduced lung function during childhood

Brazilian study reveals the effects of SARS-CoV-2 infection on the central nervous system

How are diet and exercise in bodybuilders associated with the gut microbiota and metabolites?

Researchers discover how cancer cells can turn off the immune system to help tumors grow

Shape-shifting mitochondria influence Th17 cells’ propensity for autoimmune activity

Study finds strong links between certain gut bacteria and small molecules in the blood

Study supports the importance of healthy diet for better cognitive function across races, ethnicities

The impact of the infant gut microbiome on vaccine efficacy

Role of the transketolase-like 1 gene in the development of the modern human brain

Tumor-derived factors stimulate effector trogocytosis and inhibit CAR T cells

Researchers review role of melatonin in pregnancies complicated by placental insufficiency

Recent literature reports on the role of the gut microbiome on human health and its effect on diseases

Transplanting gut bacteria from donors with sleep apnea can cause cardiovascular changes in mice

Metabolic signature could be a potential target for new breast cancer therapies

Artificial sweeteners can raise blood glucose - gut microbiome appears to explain

Exposure to blue light may accelerate aging

New method combines zero- to ultralow-field NMR with special hyperpolarization technique for detection of alcohols

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