Sleep Disorder News and Research

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A sleep disorder (somnipathy) is a medical disorder of the sleep patterns of a person or animal. Some sleep disorders are serious enough to interfere with normal physical, mental and emotional functioning. A test commonly ordered for some sleep disorders is the polysomnogram.

Study compares gene expression levels in two key hippocampal regions affected by Alzheimer's

Researchers from the Computational Intelligence Group based at the Universidad Politécnica de Madrid's Facultad de Informática have used machine learning and data mining techniques to compare gene expresssion levels in Alzheimer's disease (AD) patients in two key regions of the hippocampus: the dentate gyrus, where the disease appears to have little or no effect, and the entorhinal cortex, where Alzheimer's disease produces major neuronal damage.

10 Oct 2012

Anxiety, depression and insomnia drugs and risk of driving accident: an interview with Hui-Ju Tsai

Anxiety, depression and insomnia drugs have been commonly used to treat mental and emotional disorders, or improve sleep-related problems.

27 Sep 2012

Orexin-A hormone also affects emergence after anesthesia

A neuropeptide hormone called orexin-A—which plays an important role in regulating the normal sleep-wake cycle—also affects emergence (waking up) after anesthesia, reports an experimental study in the October issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

26 Sep 2012

REM sleep behavior disorder more common than reported

A troubling sleep disorder that causes sleepers to physically act out their dreams by kicking, screaming or falling out of bed may be more common than reported, according to Loyola University Medical Center sleep specialist Dr. Nabeela Nasir.

21 Sep 2012

Benefits limited of surgery weight loss for sleep apnea

Obese patients with obstructive sleep apnea who lose significant weight through surgery may still not be cured of their sleep disorder, study findings indicate.

20 Sep 2012

Montelukast possible surgery alternative for obstructive sleep apnea

Leukotriene modifiers may provide a noninvasive treatment option for children with nonsevere obstructive sleep apnea, say researchers.

13 Sep 2012

Modus Five launches Sleep Disorder: a Patient Education Multimedia Course

Modus Five has launched a new educational and user-friendly multimedia software program called Sleep Disorder: a Patient Education Multimedia Course. The software program presents helpful information by using rich graphics, interactive content, videos and animations.

6 Sep 2012

SSM Center for Sleep Disorders, NovaSom announce first AccuSom Deliver partnership

NovaSom, Inc., the leader in home sleep testing and cost-saving solutions for Obstructive Sleep Apnea (OSA) management, announces its first AccuSom Deliver partnership with SSM Center for Sleep Disorders, a service of SSM Health Care - St. Louis, making convenient, efficient Out-of-Center Sleep Testing (OCST) available to patients at seven locations throughout the area beginning October 1, 2012.

6 Sep 2012

BD I patients at high risk for sleep apnea

Around half of overweight patients with bipolar I disorder are at high risk for developing obstructive sleep apnea, US study results suggest.

5 Sep 2012

Sleep disorder treatment: an interview with Dr Seth Lederman, President and CEO of Tonix Pharmaceuticals

Sleep disorders are a large area. We are focused on one particular type of sleep disturbance called “non-restorative” sleep. People with this problem do sleep, but they don’t wake up feeling refreshed or feeling that their sleep has had the restorative effects of healthy sleep.

29 Aug 2012

Sleep apnea is not necessarily a male disorder

Women, particularly those with hypertension or obesity, have high rates of sleep apnea, study findings show.

24 Aug 2012

Potential treatment for sleep disorders suffered by patients with Fibromyalgia, Post-Traumatic Stress Disorder and Traumatic Brain Injury

Seth Lederman, M.D., President and CEO of New York City-based Tonix Pharmaceuticals Holding Corp. (OTCBB:TNXP) says that a good night’s sleep is a potentially powerful, but currently elusive, treatment for the chronic pain and sleep disorders suffered by patients with fibromyalgia (FM), post-traumatic stress disorder (PTSD), traumatic brain injury (TBI) and chronic traumatic encephalopathy (CTE).

16 Aug 2012

Latrepiridine reduces level of at least two neurodegeneration-related proteins in mice

14 Aug 2012

Latrepirdine demonstrates new potential against neurodegenerative conditions

The second of two studies on latrepirdine, recently published in Molecular Psychiatry, demonstrates new potential for the compound in the treatment of Alzheimer's disease, Parkinson's disease, sleep disorders, and other neurodegenerative conditions. An international team led by Mount Sinai School of Medicine scientists found that latrepiridine, known commercially as Dimebon, reduced the level of at least two neurodegeneration-related proteins in mice.

13 Aug 2012

Oximetry detects sleep disorder in stroke patients

Nocturnal oximetry is an accurate instrument for detecting and diagnosing sleep apnea syndrome in patients with stroke, research indicates.

27 Jul 2012

Insomnia: an interview with Dr Darryle Schoepp

Insomnia is a very common disorder. In medical terms it can affect a third of people. It affects elderly as well as non-elderly people, and is more common in women.

26 Jul 2012

Powerful brain chemical systems work together to paralyze skeletal muscles during REM sleep

Two powerful brain chemical systems work together to paralyze skeletal muscles during rapid eye movement (REM) sleep, according to new research in the July 11 issue of The Journal of Neuroscience. The finding may help scientists better understand and treat sleep disorders, including narcolepsy, tooth grinding, and REM sleep behavior disorder.

12 Jul 2012

Potential risk factors for disorder that causes people to kick or punch during sleep

Smoking, head injury, pesticide exposure, farming and less education may be risk factors for a rare sleep disorder that causes people to kick or punch during sleep, according to a study published in the June 27, 2012, online issue of Neurology, the medical journal of the American Academy of Neurology.

28 Jun 2012

Investigational Insomnia Medicine from Merck improved patients’ ability to fall and stay asleep according to new phase III Data

Merck (NYSE: MRK), known as MSD outside the United States and Canada, today announced new data from two pivotal Phase III efficacy trials for suvorexant, the investigational medicine Merck is developing for the treatment of insomnia. In the studies, suvorexant significantly reduced the time it took patients to fall asleep and increased the time that patients stayed asleep as early as the first night and at the three-month time point compared to placebo. The investigational medicine met statistical significance for all primary endpoints except for one measurement at Month 3 in one of the trials. These late-breaking data were presented here today at SLEEP 2012, the 26th Annual Meeting of the Associated Professional Sleep Societies.

13 Jun 2012

Oxidative stress burdens obstructive sleep apnea patients

Obstructive sleep apnea may be associated with increased oxidative burden, say researchers.

8 Jun 2012