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MerTK inhibition in leukocytes decreases tumor growth and metastasiss

The tyrosine kinase MerTK plays a prominent role in the body's immune response. MerTK signaling helps "calm" the body's first line of immunity, the macrophage, while it performs the routine duties - clearing cells that die and healing damaged tissue.

9 Jul 2013

Research shows hydrogen sulfide is a key player in colon cancer metabolism

University of Texas Medical Branch at Galveston researchers have discovered that hydrogen sulfide - the pungent-smelling gas produced by rotten eggs - is a key player in colon cancer metabolism, and a potential target for therapies for the disease.

9 Jul 2013

Mouse study identifies new treatment options for bowel cancer

Researchers have discovered the genetic processes that cause specific types of bowel cancer. Using this knowledge, they identified cancer drugs that target these genes. Their findings offer the opportunity to develop personalised treatment based on a person's genetic profile.

9 Jul 2013

Soy peptide injection dramatically reduces colon cancer metastasis in mice

After a recent University of Illinois study showed that injection of the soy peptide lunasin dramatically reduced colon cancer metastasis in mice, the researchers were eager to see how making lunasin part of the animals' daily diet would affect the spread of the disease.

9 Jul 2013

Scientists focus on the role of mutated adult neural stem cells play in human diseases

CHARGE syndrome* is a severe developmental disorder affecting multiple organs. It affects 1 in 8500 newborns worldwide. The majority of patients carry a mutation in a gene called CHD7. How this single mutation leads to the broad spectrum of characteristic CHARGE symptoms has been a mystery.

6 Jul 2013

Researchers report that aerobic exercise can lessen or worsen ulcerative colitis symptoms

Aerobic exercise can lessen - or worsen - the symptoms of inflammatory bowel diseases such as ulcerative colitis, depending on the circumstances under which the exercise is undertaken, researchers report.

3 Jul 2013

Study reveals circadian disruption is a risk factor in alcoholic liver disease

Thirty percent of severe alcoholics develop liver disease, but scientists have not been able to explain why only a subset is at risk. A research team from Northwestern University and Rush University Medical Center now has a possible explanation: disrupted sleep and circadian rhythms can push those vulnerable over the edge to disease.

2 Jul 2013

Case Comprehensive Cancer Center secures "outstanding" rating from NCI

The Case Comprehensive Cancer Center (CCCC) again demonstrated the compelling power of partnership in securing an overall rating of "outstanding" and a five-year renewal of its grant from the National Cancer Institute (NCI).

28 Jun 2013

km23-1 protein involved in spread of colon cancer may lead to new treatments for disease

Understanding how the protein km23-1 enables in the spread of colon cancer may lead to new treatments for the disease, according to researchers at Penn State College of Medicine.

28 Jun 2013

Computer simulation for predicting effectiveness of combination therapies for colon tumors

Scientist at Charité - Universitätsmedizin Berlin have used a computer simulation for predicting the effectiveness of various combination therapies for colon tumors. The study has been published in the current issue of the professional journal Molecular Systems Biology*.

28 Jun 2013

Findings suggest BRAF-mutant colon tumor cells may be less sensitive to the effect of aspirin

In 2 large studies, the association between aspirin use and risk of colorectal cancer was affected by mutation of the gene BRAF, with regular aspirin use associated with a lower risk of BRAF-wild-type colorectal cancer but not with risk of BRAF-mutated cancer, findings that suggest that BRAF-mutant colon tumor cells may be less sensitive to the effect of aspirin, according to a study in the June 26 issue of JAMA.

26 Jun 2013

Reason for large increase in hospitalizations of children with IBD unclear, researchers report

The largest investigation to date has found a dramatic increase in the number of hospitalizations for children with inflammatory bowel disease during the past decade in the United States.

26 Jun 2013

Mayo Clinic opens new C. difficile Clinic at Rochester campus

Clostridium difficile (C. difficile) has reached an epidemic state and is the most common infectious cause of diarrhea in hospitals. Health care providers are seeing increased severity and recurrence rates of the infection. In response, Mayo Clinic has opened a C. difficile Clinic at the Rochester campus.

25 Jun 2013

Rigorous interventions result in fewer infections, deaths associated with hospital-onset C. difficile

Rhode Island Hospital has reduced the incidence of hospital-associated Clostridium difficile (C. difficile) infections by 70 percent and reduced annual associated mortality in patients with hospital-associated C. difficile by 64 percent through successive implementation of five rigorous interventions , as reported in the July 2013 issue of The Joint Commission Journal on Quality and Patient Safety.

21 Jun 2013

AACE applauds the American Medical Association for recognizing obesity as disease state

The American Association of Clinical Endocrinologists (AACE) applauds the American Medical Association (AMA) House of Delegates for its action today to approve a resolution recognizing obesity as a disease state requiring a range of interventions to advance obesity treatment and prevention. AACE, the sponsor of the resolution, was joined by specialty and state medical societies in advocating for recognition of obesity as a disease state, including The Endocrine Society, American College of Cardiology, American College of Surgeons, American Urological Association, and the Texas State Delegation among many others.

19 Jun 2013

New blood test finds cancer-related microRNA in blood before tumor development

A new blood test developed in the Gastrointestinal Cancer Research Lab at Baylor Research Institute is showing very promising results for finding cancer-related microRNA in the blood before a tumor develops in the colon.

19 Jun 2013

UCLA surgeons perform minimally invasive procedure to remove large polyps and keep colon intact

Millions of people each year have polyps successfully removed during colonoscopies. But when a suspicious polyp is bigger than a marble or in a hard-to-reach location, patients are referred for surgery to remove a portion of their colon - even if doctors aren't sure whether the polyp is cancerous or not.

18 Jun 2013

Combination of cytoreductive surgery and HIPEC may reduce mortality in abdominal cancers patients

Researchers at Roswell Park Cancer Institute (RPCI) have determined that cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy (CS/HIPEC), a complex procedure to treat advanced abdominal cancers, can be done safely, and may be an effective therapy for select patients. Study results are published in the June issue of Cancer Medicine.

12 Jun 2013

Researchers discover TTC7A gene that causes multiple intestinal atresia in newborns

Physicians and researchers from Sherbrooke, Montreal and Quebec City have conducted a study that has led to the discovery of a gene that causes multiple intestinal atresia (MIA), a rare and life-threatening hereditary disorder that affects newborns.

12 Jun 2013

Viatronix's V3D-Colon software used in another clinical study relating to colorectal cancer screening

Viatronix Incorporated announced today that its dedicated CT Colonography software—V3D-Colon was exclusively used in another important clinical study relating to colorectal cancer screening.

12 Jun 2013

Colon News and Research

MerTK inhibition in leukocytes decreases tumor growth and metastasiss

Research shows hydrogen sulfide is a key player in colon cancer metabolism

Mouse study identifies new treatment options for bowel cancer

Soy peptide injection dramatically reduces colon cancer metastasis in mice

Scientists focus on the role of mutated adult neural stem cells play in human diseases

Researchers report that aerobic exercise can lessen or worsen ulcerative colitis symptoms

Study reveals circadian disruption is a risk factor in alcoholic liver disease

Case Comprehensive Cancer Center secures "outstanding" rating from NCI

km23-1 protein involved in spread of colon cancer may lead to new treatments for disease

Computer simulation for predicting effectiveness of combination therapies for colon tumors

Findings suggest BRAF-mutant colon tumor cells may be less sensitive to the effect of aspirin

Reason for large increase in hospitalizations of children with IBD unclear, researchers report

Mayo Clinic opens new C. difficile Clinic at Rochester campus

Rigorous interventions result in fewer infections, deaths associated with hospital-onset C. difficile

AACE applauds the American Medical Association for recognizing obesity as disease state

New blood test finds cancer-related microRNA in blood before tumor development

UCLA surgeons perform minimally invasive procedure to remove large polyps and keep colon intact

Combination of cytoreductive surgery and HIPEC may reduce mortality in abdominal cancers patients

Researchers discover TTC7A gene that causes multiple intestinal atresia in newborns

Viatronix's V3D-Colon software used in another clinical study relating to colorectal cancer screening

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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