Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Proof-of-concept technology using nanoparticles could offer new approach for oral medications

Since the development of insulin to manage diabetes, pharmacists have longed to create an insulin pill. Past attempts have failed because insulin does not survive the harsh conditions of the gastro-intestinal system and cannot easily cross the GI wall.

9 Aug 2018

New research shows that ketogenic diets may increase risk of Type 2 diabetes

New research published in The Journal of Physiology indicates that ketogenic diets, which are low carbohydrate high fat eating plans that are known to lead to weight loss, may cause an increased risk of Type 2 diabetes in the early stage of the diet.

9 Aug 2018

LSU Health research may lead to a change in worldwide obesity prevention strategy

A team of LSU Health New Orleans researchers has found a lower prevalence of overweight and obesity among youth in Grenada compared to US adolescents.

7 Aug 2018

Study could help explain why Asians often develop diabetes at a lower body weight

A new UC San Francisco study has discovered a key biological difference in how people of European and Chinese descent put on weight -- a finding that could help explain why Asians often develop type 2 diabetes at a much lower body weight than Caucasians.

7 Aug 2018

Offspring fed with low-protein diet during pregnancy more likely to develop prostate cancer

The offspring of females fed a low-protein diet during pregnancy and lactation are significantly more likely to develop prostate cancer as they age.

7 Aug 2018

Medicaid expansion increases access to diabetes treatment

Prescriptions for diabetes medications increased in the first two years after states expanded eligibility for Medicaid as part of the Affordable Care Act, compared to states that didn't expand Medicaid.

7 Aug 2018

Medicaid expansion making diabetes meds more accessible to poor, study shows

Low-income people with diabetes are better able to afford their medications and manage their disease in states that expanded Medicaid under the Affordable Care Act, a new study suggests.

6 Aug 2018

Probiotic use could result in disorienting brain fogginess and rapid belly bloating

Probiotic use can result in a significant accumulation of bacteria in the small intestine that can result in disorienting brain fogginess as well as rapid, significant belly bloating, investigators report.

6 Aug 2018

IU researchers receive $1.5 million NIH grant to advance study on diabetes risks

A $1.5 million grant from the National Institutes of Health will advance work by Indiana University researchers that seeks to identify Americans at risk for diabetes and other metabolic disorders based on their exposure to trace minerals in the environment.

3 Aug 2018

Claudia Langenberg wins Helmholtz International Fellow Award

"Claudia Langenberg is known for her research on genetic causes of insulin resistance, type 2 diabetes and related metabolic disorders," explains Dr. Gabi Kastenmüller, acting head of the Institute of Bioinformatics and Systems Biology.

3 Aug 2018

Insulin resistance largely undetected in non-diabetic patients with Parkinson's disease

Almost two-thirds of non-diabetic patients with Parkinson's disease may be insulin resistant, despite having normal blood sugar, report scientists in the Journal of Parkinson's Disease.

3 Aug 2018

New nuclear medicine test could improve care of patients with type 1 diabetes

Researchers have discovered a new nuclear medicine test that could improve care of patients with type 1 diabetes. The new positron emission tomography imaging method could measure beta-cell mass, which would greatly enhance the ability to monitor and guide diabetes therapies.

3 Aug 2018

Researchers use DNA editing tool to reveal mechanisms behind autoimmune diseases

A group of researchers at the University of São Paulo in Brazil used a DNA editing tool called CRISPR/Cas9 to manipulate on of the genes associated to the autoaggressive T lymphocytes responsible for inducing autoimmune diseases such as autoimmune polyglandular syndrome type 1 and type 1 diabetes.

2 Aug 2018

Trying to pinpoint hurricane’s true toll, researchers say 1,139 died in Puerto Rico

The question of how many people perished after Hurricane Maria in Puerto Rico has stirred controversy because of the wide discrepancies between the territory's official count and independent reports. Now, two researchers have added a new tally that uses the island government's own data but far outpaces its death estimate.

2 Aug 2018

Researchers uncover new mechanisms underlying common kidney cancer in children

Connecting two previously unrelated insights about the formation of pediatric kidney cancer, researchers at UT Southwestern Medical Center have uncovered the means by which the cancer continues to grow, providing potential targets for more effective treatments in the future.

2 Aug 2018

Exenatide treatment improves depression symptoms in PD patients

Non-motor symptoms of Parkinson's disease, such as depression, apathy, cognitive impairment, sleep disorders, and sensory symptoms, can have a greater impact on health-related quality of life than motor deficits.

1 Aug 2018

Glaucoma Research Foundation-funded research makes breakthrough in treatment of glaucoma

Glaucoma Research Foundation, a national non-profit organization dedicated to finding a cure for glaucoma, today announced a team of neuroscience researchers, led by Adriana Di Polo, PhD, at University of Montreal, have made a major breakthrough in the treatment of glaucoma.

31 Jul 2018

Study: Brief period of inactivity can trigger diabetic symptoms in vulnerable patients

Just two weeks without much activity can have a dramatic impact on health from which it is difficult to recover, according to researchers who studied overweight older adults at risk of developing Type 2 diabetes.

31 Jul 2018

CNDA approves KEYTRUDA for treatment of advanced melanoma

Merck, known as MSD outside the United States and Canada, today announced that KEYTRUDA, Merck's anti-PD-1 therapy, has been approved by the China National Drug Administration for the treatment of adult patients with unresectable or metastatic melanoma following failure of one prior line of therapy.

26 Jul 2018

Phase 3 study of KEYTRUDA monotherapy meets primary endpoint

Merck, known as MSD outside the United States and Canada, announced today that the pivotal Phase 3 KEYNOTE-048 trial investigating KEYTRUDA, Merck's anti-PD-1 therapy, for first-line treatment of recurrent or metastatic head and neck squamous cell carcinoma, met a primary endpoint of overall survival as monotherapy in patients whose tumors expressed PD-L1.

25 Jul 2018

Insulin News and Research

Further Reading

Proof-of-concept technology using nanoparticles could offer new approach for oral medications

New research shows that ketogenic diets may increase risk of Type 2 diabetes

LSU Health research may lead to a change in worldwide obesity prevention strategy

Study could help explain why Asians often develop diabetes at a lower body weight

Offspring fed with low-protein diet during pregnancy more likely to develop prostate cancer

Medicaid expansion increases access to diabetes treatment

Medicaid expansion making diabetes meds more accessible to poor, study shows

Probiotic use could result in disorienting brain fogginess and rapid belly bloating

IU researchers receive $1.5 million NIH grant to advance study on diabetes risks

Claudia Langenberg wins Helmholtz International Fellow Award

Insulin resistance largely undetected in non-diabetic patients with Parkinson's disease

New nuclear medicine test could improve care of patients with type 1 diabetes

Researchers use DNA editing tool to reveal mechanisms behind autoimmune diseases

Trying to pinpoint hurricane’s true toll, researchers say 1,139 died in Puerto Rico

Researchers uncover new mechanisms underlying common kidney cancer in children

Exenatide treatment improves depression symptoms in PD patients

Glaucoma Research Foundation-funded research makes breakthrough in treatment of glaucoma

Study: Brief period of inactivity can trigger diabetic symptoms in vulnerable patients

CNDA approves KEYTRUDA for treatment of advanced melanoma

Phase 3 study of KEYTRUDA monotherapy meets primary endpoint

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