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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Genome analysis of alphacoronavirus and betacoronavirus species from South Korean bats

Researchers performed genomic comparisons between alphacoronaviruses (αCoVs) and betacoronaviruses (βCoVs) originating from South Korean Bats.

28 Jun 2022

The potential of DNA-based SARS-CoV-2 vaccine candidates

Researchers evaluated the immunogenicity of DNA-based candidate vaccines against SARS-CoV-2 in mice.

28 Jun 2022

Researchers identify an epigenetic signature associated to the development of MIS-C after COVID-19

Researchers from the Cancer Epigenetics group led by Dr. Manel Esteller at the Josep Carreras Leukaemia Research Institute and Dr. Aurora Pujol, from the Bellvitge Biomedical Research Institute, have identified an epigenetic signature associated to the development of the Multisystem Inflammatory Syndrome in Children (MIS-C) after a SARS-CoV-2 virus infection.

27 Jun 2022

Study opens a door to better understanding the role of viruses in ecology

The first discovery of viruses infecting a group of microbes that may include the ancestors of all complex life has been found, researchers at The University of Texas at Austin report in Nature Microbiology.

27 Jun 2022

Studies discover multiple gene variants that contribute to the risk and severity of NAFLD in children

In a pair of overlapping studies, a diverse team of researchers, led by scientists at University of California San Diego School of Medicine, have deepened investigations into the genetic origins of nonalcoholic fatty liver disease (NAFLD) in children, describing multiple gene variants (including some previously unknown) that contribute to the risk of developing NAFLD and gene variants associated with the severity of the liver disease.

27 Jun 2022

Lipid-peptide nanocomplexes offer new mRNA platform

A new paper reports the methodical development of lipid-peptide nanocomplexes as a delivery vehicle for messenger ribonucleic acid molecules to the tumor cell, in vitro and in vivo.

27 Jun 2022

Study discovers microbial link between Western-style diet and colorectal cancer risk

New research builds the case that a Western-style diet -; rich in red and processed meat, sugar and refined grains/carbohydrates -; is tied to higher risk of colorectal cancer through the intestinal microbiota. Investigators from Brigham and Women's Hospital with collaborators looked at data from more than 134,000 participants from two U.S.-wide prospective cohort studies.

27 Jun 2022

Using genomics to restore degraded ecosystems

The monumental global task to restore degraded ecosystems will need to include sophisticated technologies such as environmental DNA monitoring to understand and support the recovery of complex biospheres, international researchers say.

27 Jun 2022

Review and case study illustrates the challenges of monkeypox

A new paper published in Travel Medicine and Infectious Disease reviews the history of this disease in and outside Africa, with special reference to its clinical difficulties.

27 Jun 2022

Comparison of genome sequences of SARS-CoV-2 and other coronaviruses

Researchers compared the genomic sequence of SARS-CoV-2 and that of different coronaviruses.

27 Jun 2022

Mice study unravels the role of T. denticola in Alzheimer's disease pathogenesis

Tau hyperphosphorylation is the key characteristic pathological hallmarks of Alzheimer's disease (AD). Recently studies showed periodontitis and periodontal pathogen are significant risk factors for AD.

26 Jun 2022

Scientists identify new genetic disease that delays children's intellectual development

Scientists have identified a new genetic disease, which causes some children's brains to develop abnormally, resulting in delayed intellectual development.

24 Jun 2022

New nanoparticles effectively stopped the growth and spread of ovarian, liver tumors in mice

As they grow, solid tumors surround themselves with a thick, hard-to-penetrate wall of molecular defenses. Getting drugs past that barricade is notoriously difficult.

24 Jun 2022

Epstein-Barr virus can reactivate in long COVID

In a recent study posted to the medRxiv* preprint server, researchers at the University of California, San Francisco, and Monogram Biosciences examined the connections between the post-acute sequelae of coronavirus disease 2019 (COVID-19) (PASC) and Epstein-Barr virus (EBV) reactivation.

23 Jun 2022

Overlap in pro-inflammatory genes and pathways between COVID-19 and MIS-C

In a recent study posted to the medRxiv* pre-print server, researchers in the United States characterized differential host immune responses in acute coronavirus disease 2019 (COVID-19) and multisystem inflammatory syndrome in children (MIS-C) to inform future development of novel biomarkers for both diseases.

23 Jun 2022

"Founder events" that reduced genetic diversity found to be common throughout human history

Human populations have waxed and waned over the millennia, with some cultures exploding and migrating to new areas or new continents, others dropping to such low numbers that their genetic diversity plummeted.

23 Jun 2022

Newly identified gene may be responsible for sex-linked effects on women's heart disease outcomes

When diagnostic tests for the heart were first created, scientists at the time did not fully consider that no two bodies are the same, especially between the sexes.

23 Jun 2022

Researchers improve the ability of a protein to repair oxidative DNA damage

Researchers at Karolinska Institutet and SciLifeLab in Sweden describe in a study published in Science how they have improved the ability of a protein to repair oxidative DNA damage and created a new protein function.

23 Jun 2022

Bacterium discovery helps to solve the puzzle of what factors limit cell size

On sunken leaves in the waters of a Caribbean mangrove swamp, researchers discovered a bacterium that challenges the prevailing view of bacterial cell size; counter to the notion that microbes are only visible with a microscope, this one – named Thiomargarita magnifica – is larger than all other known giant bacteria by ~50-fold, and can be seen by the naked eye, the study's authors say.

23 Jun 2022

New method helps unravel three-dimensional structure of the human genome

Weill Cornell Medicine and New York Genome Center researchers, in collaboration with Oxford Nanopore Technologies, have developed a new method to assess on a large scale the three-dimensional structure of the human genome, or how the genome folds.

23 Jun 2022

DNA News and Research

Further Reading

Genome analysis of alphacoronavirus and betacoronavirus species from South Korean bats

The potential of DNA-based SARS-CoV-2 vaccine candidates

Researchers identify an epigenetic signature associated to the development of MIS-C after COVID-19

Study opens a door to better understanding the role of viruses in ecology

Studies discover multiple gene variants that contribute to the risk and severity of NAFLD in children

Lipid-peptide nanocomplexes offer new mRNA platform

Study discovers microbial link between Western-style diet and colorectal cancer risk

Using genomics to restore degraded ecosystems

Review and case study illustrates the challenges of monkeypox

Comparison of genome sequences of SARS-CoV-2 and other coronaviruses

Mice study unravels the role of T. denticola in Alzheimer's disease pathogenesis

Scientists identify new genetic disease that delays children's intellectual development

New nanoparticles effectively stopped the growth and spread of ovarian, liver tumors in mice

Epstein-Barr virus can reactivate in long COVID

Overlap in pro-inflammatory genes and pathways between COVID-19 and MIS-C

"Founder events" that reduced genetic diversity found to be common throughout human history

Newly identified gene may be responsible for sex-linked effects on women's heart disease outcomes

Researchers improve the ability of a protein to repair oxidative DNA damage

Bacterium discovery helps to solve the puzzle of what factors limit cell size

New method helps unravel three-dimensional structure of the human genome

eBook: A guide to RNA sequencing eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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