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New CRISPR-Cas9 approach confers protection from ischemia/reperfusion injury

A new CRISPR-Cas9 approach that targets a detrimental signaling pathway in the heart confers protection from ischemia/reperfusion injury, according to a study in mice.

12 Jan 2023

CNB-CSIC vaccine fully protects against SARS-CoV-2 infection of the brain

In a recent study published in the journal Nature Neuroscience, researchers in Spain described the effectiveness of a modified vaccinia virus Ankara (MVA) vector severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine candidate in protecting against SARS-CoV-2 infection in the brain using a mouse model.

12 Jan 2023

American Cancer Society's annual report on cancer facts and trends released

Today, the American Cancer Society released Cancer Statistics, 2023, the organization's annual report on cancer facts and trends. According to the report, overall cancer mortality has dropped 33% since 1991, averting an estimated 3.8 million cancer deaths.

12 Jan 2023

Machine learning-based behavioral intervention can improve end-of-life cancer care

Electronic nudges delivered to health care clinicians based on a machine learning algorithm that predicts mortality risk quadrupled rates of conversations with patients about their end-of-life care preferences, according to the long-term results of a randomized clinical trial published by Penn Medicine investigators in JAMA Oncology today.

12 Jan 2023

Mediterranean diet reduces dietary inflammation scores after six months

A new study looked at the effects of replacing the habitual diet with the Mediterranean diet for six months in older Australians.

12 Jan 2023

The same genetic factors may contribute to both cardiometabolic diseases and dementia

Being affected by several cardiometabolic diseases such as diabetes, heart disease and stroke, is linked to a greatly increased risk of dementia and Alzheimer's disease.

12 Jan 2023

Recent progress in the understanding of neuraminidase-specific antibodies for the development of universal influenza vaccines

A recent study published in Viruses reviewed the characteristics of neuraminidase with emphasis on the development of NA-based universal influenza vaccines.

12 Jan 2023

Bleeding and in pain, a pregnant woman in Louisiana couldn’t get answers

When Kaitlyn Joshua found out she was pregnant in mid-August, she and her husband, Landon Joshua, were excited to have a second baby on the way. They have a 4-year-old daughter and thought that was just the right age to help with a younger sibling.

12 Jan 2023

Study evaluates the efficacy of complementary use of corticosteroid treatment for community-acquired pneumonia

Announcing a new publication for Acta Materia Medica journal. The objective of this study was to systematically evaluate the clinical efficacy of the complementary use of corticosteroids in the treatment of community-acquired pneumonia (CAP).

11 Jan 2023

Investigational T-cell therapy shows antiviral efficacy and safety in cancer patients treated with stem cell transplant

Posoleucel, an investigational allogeneic off-the-shelf T-cell therapy that simultaneously targets six different viruses, demonstrated promising antiviral efficacy and safety in a phase II study of patients who had undergone stem cell transplantation to treat their cancer or other blood diseases.

11 Jan 2023

Green tea may protect against telomere shortening due to biological aging

A new study in Scientific Reports aimed to analyze the association between cross-section and longitudinal LTL changes with the consumption of soft drinks, coffee, and tea among middle-aged and older Korean men and women for six years. It also assessed any changes in the association results according to a difference in sex and age groups.

11 Jan 2023

Study identifies LAP1 as a master regulator of nuclear envelope remodeling during melanoma progression

Researchers discovered that the elevated expression of LAP1, an inner nuclear membrane protein, helps metastatic melanoma cells surmount the physical challenges presented by tissue structure and the microenvironment during metastasis.

11 Jan 2023

Lifestyle and genetic factors influence risk of cardiovascular complications after COVID-19

Researchers examined the contribution of lifestyle and genetic factors to cardiovascular and thromboembolic event (CVE) risk following coronavirus disease 2019 (COVID-19).

11 Jan 2023

Real-world effectiveness of the bivalent vaccine for preventing COVID-19 hospitalizations in non-hospitalized subjects

Researchers investigated the efficacy of a booster dose of the bivalent mRNA COVID-19 vaccine in preventing severe outcomes during SARS-CoV-2 infections.

11 Jan 2023

Review shows metformin usage to be associated with better COVID-19 outcomes

Researchers reported on the potential association between metformin usage and coronavirus disease 2019 (COVID-19) outcomes.

11 Jan 2023

MIS-C more common and severe than previously thought

In a recent study published in the JAMA Network Open journal, researchers compared the characteristics of multisystem inflammatory syndrome in children (MIS-C) and coronavirus disease 2019 (COVID-19).

10 Jan 2023

Men who lack interest in sex are at heightened risk of premature death

A recent study published in the journal PLOS ONE evaluated the association between sexual interest and mortality.

10 Jan 2023

Spike protein mutations in Omicron subvariants increase their susceptibility to reductive cleavage of disulfide bonds

Researchers discovered that the spike protein of SARS-CoV-2 is susceptible to cleavage at the disulfide bonds, and the vulnerability to reductive cleavage varies across variants, with the Omicron variant family being highly susceptible to reduction.

10 Jan 2023

Researchers review bacteriophage treatment

Researchers presented an overview of bacteriophage treatment, including mechanisms, types, design and applications of bacteriophage therapy.

10 Jan 2023

What were the risks and patterns of childhood deaths before and during the COVID-19 pandemic?

A new study describes the pattern of childhood deaths over 2019-21, the first two years of the pandemic, hoping to help identify the risks associated with these events.

10 Jan 2023

Mortality News and Research

New CRISPR-Cas9 approach confers protection from ischemia/reperfusion injury

CNB-CSIC vaccine fully protects against SARS-CoV-2 infection of the brain

American Cancer Society's annual report on cancer facts and trends released

Machine learning-based behavioral intervention can improve end-of-life cancer care

Mediterranean diet reduces dietary inflammation scores after six months

The same genetic factors may contribute to both cardiometabolic diseases and dementia

Recent progress in the understanding of neuraminidase-specific antibodies for the development of universal influenza vaccines

Bleeding and in pain, a pregnant woman in Louisiana couldn’t get answers

Study evaluates the efficacy of complementary use of corticosteroid treatment for community-acquired pneumonia

Investigational T-cell therapy shows antiviral efficacy and safety in cancer patients treated with stem cell transplant

Green tea may protect against telomere shortening due to biological aging

Study identifies LAP1 as a master regulator of nuclear envelope remodeling during melanoma progression

Lifestyle and genetic factors influence risk of cardiovascular complications after COVID-19

Real-world effectiveness of the bivalent vaccine for preventing COVID-19 hospitalizations in non-hospitalized subjects

Review shows metformin usage to be associated with better COVID-19 outcomes

MIS-C more common and severe than previously thought

Men who lack interest in sex are at heightened risk of premature death

Spike protein mutations in Omicron subvariants increase their susceptibility to reductive cleavage of disulfide bonds

Researchers review bacteriophage treatment

What were the risks and patterns of childhood deaths before and during the COVID-19 pandemic?

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