Colon News and Research

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Insights into tissue-based T cells

US researchers have, for the first time, characterized T cells located in human tissues, rather than in the blood.

31 Dec 2012

Surgeons: Support your low-income neighbor

Patients with cancer in low-income nations present for surgical treatment at a young age, advanced stage of disease, and often receive palliative rather than curative procedures, suggests a study in Malawi.

28 Dec 2012

The war on terror: High rates of stoma creation after colorectal injury

Over one third of military personnel in Iraq and Afghanistan who sustain colorectal injury undergo fecal diversion, show coalition force data.

20 Dec 2012

Patients with hypertension or diabetes have increased risk of cancer recurrence, survival

By all accounts, a combination of colon cancer, diabetes and high blood pressure can be a recipe for medical disaster. Now, a new study led by a surgical oncologist and researcher at Temple University School of Medicine and Fox Chase Cancer Center has shown just how deadly this mix can be.

20 Dec 2012

Numerous treatments exist for cancer-related fatigue, but few doctors recommend them to patients

Many people who have been through cancer and its treatment have trouble with their recovery because of severe, debilitating fatigue that can last for months or even years. But even though a variety of treatments exist for cancer-related fatigue, few doctors are recommending them to patients, according to a recent Mayo Clinic study appearing in Supportive Care in Cancer.

19 Dec 2012

Targeting km23-1 protein may slow the spread of cancer cells

The spread of cancer cells may be slowed by targeting the protein km23-1, according to researchers at Penn State College of Medicine.

19 Dec 2012

Budding yeast an acceptable model system to study KP1019 anti-cancer drug

Researchers have found that the budding yeast (Saccharomyces cerevisiae) is an acceptable model system to study KP1019, an anti-cancer drug that uses ruthenium, a rare metal, a new study found. Researchers had previously been interested in studying KP1019 because it is believed to cause cancer cell death and is not known to have negative secondary side effects for healthy tissues.

19 Dec 2012

Study finds new evidence that vitamin D decreases risk of autism in children

A study just published online in the peer-reviewed journal Dermato-Endocrinology found additional evidence that vitamin D reduces the risk of developing autism.

14 Dec 2012

Biological factors, cell behaviour drive tumour growth contributing to therapy failure and relapse

Cancer scientists led by Dr. John Dick at the Princess Margaret Cancer Centre have found a way to follow single tumour cells and observe their growth over time. By using special immune-deficient mice to propagate human colorectal cancer, they found that genetic mutations, regarded by many as the chief suspect driving cancer growth, are only one piece of the puzzle. The team discovered that biological factors and cell behaviour - not only genes - drive tumour growth, contributing to therapy failure and relapse.

14 Dec 2012

Researchers discover two-faced group of cells at work in human colon cancer

Northwestern Medicine researchers have discovered a "two-faced" group of cells at work in human colon cancer, with opposing functions that can suppress or promote tumor growth. These cells are a subset of T-regulatory (Treg) cells, known to suppress immune responses in healthy individuals.

14 Dec 2012

Study finds many patients with family history of LINE-1 hypomethylated colorectal cancer

When people with a family history of colorectal cancer develop the disease, their tumors often carry a molecular sign that the cancer could be life-threatening and may require aggressive treatment, Dana-Farber Cancer Institute scientists report in a new study.

13 Dec 2012

SIRT6 protein may play a critical role in blocking cancer and controlling cellular metabolism

A new study sheds more light on how an anti-aging gene suppresses cancer growth, joint University of Michigan Health System and Harvard Medical School research shows.

11 Dec 2012

NCI-funded study to identify metabolic vulnerabilities of particularly aggressive cancers

Eileen White, PhD, associate director for basic science at The Cancer Institute of New Jersey and professor of molecular biology and biochemistry at Rutgers, The State University of New Jersey, and colleagues from Princeton University have been awarded a new five-year, $2.4 million dollar research grant from the National Cancer Institute.

7 Dec 2012

Rice bran offers promising cancer prevention properties

A recent University of Colorado Cancer Center review in the journal Advances in Nutrition shows that rice bran offers promising cancer prevention properties. Meanwhile, an ongoing clinical trial is testing the effectiveness of rice bran in preventing the recurrence of colon cancer.

6 Dec 2012

Combining 5-fluorouracil and IL-1 beta inhibitor can improve effectiveness of chemotherapy

These results reveal how the immune system can then limit the effectiveness of some cancer chemotherapies. The researchers now intend to block the molecules responsible for negative immune system activation to increase the efficiency of chemotherapy. A clinical trial to test this hypothesis should begin very soon.

5 Dec 2012

Scientists sequence DNA of biopsied tissue from colon polyps

The causes underlying the development of certain types of common cancers have not yet been elucidated. In order to better determine the origin and the sequence of events responsible for the onset of colon cancer, the teams led by Thanos Halazonetis and Stylianos Antonarakis, professors at the University of Geneva (UNIGE), Switzerland, have sequenced the DNA of biopsied tissue from colon polyps.

2 Dec 2012

Men should see a doctor and be proactive about their health, say UAB experts

Experts at the University of Alabama at Birmingham (UAB) say a man's tendency to wait until the onset of sickness to see his doctor is a major detriment to health because key screenings are missed.

1 Dec 2012

Mistletoe extract plays a vital role in treating colon cancer

Mistletoe has become an important symbol of Christmas but it also has the potential to play a vital role as an alternative therapy for sufferers of colon cancer.

30 Nov 2012

Infrared therapy could help prevent anal cancer in HIV-positive population

Infrared coagulopathy treatment of a potential precursor of anal cancer is effective and warrants further study as a way to reduce anal cancer incidence and mortality among HIV-infected people, report researchers.

30 Nov 2012

Diabetes education critical for uncontrolled high blood sugar people with cancer

When people with Type 2 diabetes are diagnosed with cancer -- a disease for which they are at higher risk -- they ignore their diabetes care to focus on cancer treatment, according to new Northwestern Medicine- research. But uncontrolled high blood sugar is more likely to kill them and impairs their immune system's ability to fight cancer.

30 Nov 2012

Colon News and Research

Insights into tissue-based T cells

Surgeons: Support your low-income neighbor

The war on terror: High rates of stoma creation after colorectal injury

Patients with hypertension or diabetes have increased risk of cancer recurrence, survival

Numerous treatments exist for cancer-related fatigue, but few doctors recommend them to patients

Targeting km23-1 protein may slow the spread of cancer cells

Budding yeast an acceptable model system to study KP1019 anti-cancer drug

Study finds new evidence that vitamin D decreases risk of autism in children

Biological factors, cell behaviour drive tumour growth contributing to therapy failure and relapse

Researchers discover two-faced group of cells at work in human colon cancer

Study finds many patients with family history of LINE-1 hypomethylated colorectal cancer

SIRT6 protein may play a critical role in blocking cancer and controlling cellular metabolism

NCI-funded study to identify metabolic vulnerabilities of particularly aggressive cancers

Rice bran offers promising cancer prevention properties

Combining 5-fluorouracil and IL-1 beta inhibitor can improve effectiveness of chemotherapy

Scientists sequence DNA of biopsied tissue from colon polyps

Men should see a doctor and be proactive about their health, say UAB experts

Mistletoe extract plays a vital role in treating colon cancer

Infrared therapy could help prevent anal cancer in HIV-positive population

Diabetes education critical for uncontrolled high blood sugar people with cancer

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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