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EMA recommends first all-oral treatment to tackle deadly sleeping sickness

The European Medicines Agency's Committee for Medicinal Products for Human Use has adopted a positive scientific opinion of fexinidazole, the first all-oral treatment that has been shown to be efficacious for both stages of sleeping sickness.

16 Nov 2018

Mechanisms that govern HIV latency differ in the gut and blood, finds study

Mechanisms that govern HIV transcription and latency differ in the gut and blood, according to a study published November 15 in the open-access journal PLOS Pathogens by Steven Yukl of San Francisco Veterans Affairs Medical Center and the University of California, San Francisco, and colleagues.

16 Nov 2018

IDSA guidelines: Review by ID physician improves outcomes for outpatient parenteral antimicrobial therapy

Before patients receive intravenous antimicrobial infusion therapy outside of the hospital - whether at home, a doctor's office or a skilled nursing facility - an infectious diseases specialist should review the order to ensure the most appropriate treatment, suggest updated guidelines released by the Infectious Diseases Society of America.

14 Nov 2018

An underused strategy for surge in STDs: Treat patients’ partners without a doctor visit

If patients return to Dr. Crystal Bowe soon after taking medication for a sexually transmitted infection, she usually knows the reason: Their partners have re-infected them.

13 Nov 2018

New single-dose antibiotic effectively treats uncomplicated gonorrhea infections

A phase 2 clinical trial led by Stephanie N. Taylor, MD, Professor of Medicine and Microbiology in the Section of Infectious Diseases at LSU Health New Orleans School of Medicine, has found that a new antibiotic effectively treats uncomplicated urogenital and rectal gonorrhea infections in a single oral dose.

9 Nov 2018

New study does not support hypertensive effect from urate elevation

A study from a group of Massachusetts General Hospital investigators may reduce the concern that elevating levels of urate, an approach being investigated to treat several neurodegenerative disorders, could increase the risk of hypertension.

8 Nov 2018

Monash researchers provide insight into intricate peptide changes affecting immune system

Human leukocyte antigen molecules are a group of proteins that help the immune system identify foreign invaders such as viruses and bacteria and which impact a wide variety of clinical outcomes including infection and cancer.

8 Nov 2018

Oral antibiotic shows promise to cure uncomplicated gonorrhea

An investigational oral antibiotic called zoliflodacin was well-tolerated and successfully cured most cases of uncomplicated gonorrhea when tested in a Phase 2 multicenter clinical trial, according to findings published today in the New England Journal of Medicine.

8 Nov 2018

HIV-2 is more pathogenic than previously demonstrated, finds study

A study published in The Lancet HIV shows that HIV-2 is more pathogenic than previously demonstrated. The new findings indicate that early treatment should be applied to all patients with HIV, not only to those with HIV-1.

7 Nov 2018

ECDC study estimates burden of infections caused by antibiotic-resistant bacteria

An ECDC study estimates the burden of five types of infections caused by antibiotic-resistant bacteria of public health concern in the European Union and in the European Economic Area.

6 Nov 2018

New encyclopedia for adult and pediatric neuropsychological disorders

John DeLuca, PhD, a clinical neuropsychologist and Senior Vice President of Research and Training at Kessler Foundation, is the co-chief editor of the new 2nd edition "Encyclopedia of Clinical Neuropsychology". Published by Springer, it is the first major encyclopedia of adult and pediatric neuropsychological disorders.

2 Nov 2018

Scientists pinpoint TIM-3 protein as next potential target for immunotherapy treatments

Following the 2018 Nobel Prize for Medicine, global attention is now more than ever turned toward the promise of immunotherapy in oncology. An international team’s work has shed new light on a molecule called TIM-3 that might play a key role in the regulation of the immune response.

31 Oct 2018

PrEP shown to be safe and effective for widespread use

New research presented at the HIV Drug Therapy Conference in Glasgow today shows that pre-exposure prophylaxis could be given to millions of people worldwide with no increased risk of safety issues during treatment.

30 Oct 2018

Investigational drug targeting the opioid system may help reduce symptoms of major depression

Two clinical trials of an investigational drug that targets the opioid system support its safety and effectiveness in reducing symptoms of major depression, when added to standard antidepressant treatment.

29 Oct 2018

New method increases virus production in cells to generate more vectors for gene transfer

Researchers at Tokyo Medical and Dental University have established a method to increase the released lentiviral particles produced by host cells, which will aid the use of the vectors for introducing foreign genes into cells

29 Oct 2018

Getting right level of leptin may help protect cardiovascular health

Like that famous bowl of porridge, when leptin levels are "just right" they help protect our cardiovascular health, scientists say.

29 Oct 2018

New approach may lead to protective vaccines for immunocompromised patients

A study led by Som Nanjappa at the University of Illinois College of Veterinary Medicine identifies a cellular target that may improve efficacy in vaccines designed to protect immunocompromised individuals from potentially deadly opportunistic infections.

26 Oct 2018

HIV News and Research

EMA recommends first all-oral treatment to tackle deadly sleeping sickness

Mechanisms that govern HIV latency differ in the gut and blood, finds study

IDSA guidelines: Review by ID physician improves outcomes for outpatient parenteral antimicrobial therapy

An underused strategy for surge in STDs: Treat patients’ partners without a doctor visit

New single-dose antibiotic effectively treats uncomplicated gonorrhea infections

New study does not support hypertensive effect from urate elevation

Monash researchers provide insight into intricate peptide changes affecting immune system

Oral antibiotic shows promise to cure uncomplicated gonorrhea

HIV-2 is more pathogenic than previously demonstrated, finds study

ECDC study estimates burden of infections caused by antibiotic-resistant bacteria

New encyclopedia for adult and pediatric neuropsychological disorders

Scientists pinpoint TIM-3 protein as next potential target for immunotherapy treatments

PrEP shown to be safe and effective for widespread use

Investigational drug targeting the opioid system may help reduce symptoms of major depression

New method increases virus production in cells to generate more vectors for gene transfer

Getting right level of leptin may help protect cardiovascular health

New approach may lead to protective vaccines for immunocompromised patients

STIs being diagnosed in young adults every four minutes in the UK

HPTN 075 study shows high risk of HIV infection among MSM and TGW in sub-Saharan Africa

Global HIV Vaccine Enterprise launches strategy to accelerate development of effective HIV vaccine

Exploring the G:Box and for high-quality imaging

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

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