Atherosclerosis News and Research

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Atherosclerosis is the progressive buildup of plaque - the fatty deposits and other cells - in the inner walls of the arteries. The condition is a consequence of elevated cholesterol and for many it's a silent disease, with no visible signs or symptoms. The disease can begin in early adulthood and continues to progress for the rest of a person's life. Despite the serious nature of atherosclerosis, many people do not understand how it develops and progresses.

Impaired endothelial function is an early indicator of atherosclerosis

Impaired endothelial function is an early indicator of atherosclerosis according to a study of healthy people followed from childhood to young adulthood reported in Circulation: Journal of the American Heart Association.

25 Oct 2004

Newly discovered gene could be a significant contributor to diabetes in Americans

A gene involved in the action of insulin is associated with type 2 diabetes and the body’s response to insulin, report scientists at Wake Forest University Baptist Medical Center.

25 Oct 2004

Gene variations explain why people with type 2 diabetes are at much greater risk for coronary artery disease

New studies by an international team of scientists led by Joslin Diabetes Center have found variations in a gene that help explain why people with type 2 diabetes are at much greater risk for coronary artery disease, the leading cause of death for this group.

21 Oct 2004

Biomedical engineers receive $11.5 million to study how white blood cells navigate

We all know the power of touch: A whack on the skull – or a hug – can convey more information than other forms of communication ever can. It turns out the same is true inside our bodies

12 Oct 2004

Study raises important questions about the use of drugs that promote or prevent angiogenesis

Dartmouth Medical School cardiology researchers have discovered a new mechanism for what drives the growth of muscle tissue in the lining of injured heart vessels that can eventually lead to blockage.

11 Oct 2004

Study increases likelihood that MRI could be used as predictive technology to determine which patients should be placed on statin therapy for atherosclerosis

Using modified magnetic resonance imaging (MRI) techniques, researchers at Johns Hopkins have been able to detect the early benefits of a cholesterol-lowering medication much sooner than before.

11 Oct 2004

Atheromatosis, which lies behind heart attacks, stroke, and other cardiovascular problems, has a major impact on public health

These two diseases are completely different from each other, but they do have one common denominator: inflammation. Researchers at Lund University in Sweden can now show that it might also be possible to treat them with the same drug.

10 Oct 2004

Low-dose estrogen therapy significantly reduced the progression of fatty buildup in the arteries leading to the heart

“We’ve shown that you can get the same reduction in coronary artery atherosclerosis with standard-dose or low-dose estrogen,” said Thomas B. Clarkson, D.V.M., one of the investigators. “It is very significant.”

10 Oct 2004

Diet high in soy could be good for the hearts and bones of premenopausal women

The results suggest that for cholesterol and bone density, the natural plant estrogens in soy may be most effective in conjunction with the body’s own estrogen – which would make it especially potent in women who haven’t reached menopause. They also point to the possibility the estrogen-soy synergy could have other benefits as well.

10 Oct 2004

Lipid profile differences explain why two people with the same overall cholesterol level can have different degrees of cardiovascular disease

When it comes to lipid profiles -- a key measure of heart disease risk-- it appears that African-Americans and women have it better than whites and men, according to a new study by Duke University Medical Center researchers.

7 Oct 2004

Research continues to show the cardiovascular benefits of fish consumption or omega-3 fatty acids

USA-Peer-reviewed research continues to show the cardiovascular benefits of fish consumption or intake of long-chain omega-3 polyunsaturated fatty acids (n-3 LC-PUFAs).

5 Oct 2004

Interleukin-6 has potential as a therapeutic drug in treating metabolic disorders such as obesity, type 2 diabetes and atherosclerosis

For the most of the past century, researchers have searched for a muscle-contraction-induced factor, which mediates some of the exercise effects in other tissues and organs such as the liver and adipose tissue.

5 Oct 2004

Sibling history is a better predictor of coronary heart disease than parental history or traditional risk factor scoring

Researchers at Johns Hopkins have found that sibling history -- whether or not a brother or sister had early heart disease -- is a better predictor of a person's likelihood of developing coronary heart disease than parental history or traditional risk factor scoring.

4 Oct 2004

Clusters of genes within human aortas appear to predict risk for atherosclerosis

Duke University Medical Center researchers have identified specific clusters of genes within human aortas that appear to predict with great specificity which patients may be at highest risk for developing atherosclerosis, as well as the severity of the disease.

28 Sep 2004

Guidant announces plans to initiate vulnerable plaque study

Guidant has announced plans to conduct a study designed to increase clinical understanding of “vulnerable” plaques – lipid-rich coronary lesions that suddenly rupture – that may cause most heart attacks.

27 Sep 2004

Terror fears raise women's level of protein linked to heart disease

Israeli women with chronic fears of terror attacks have higher levels of a blood protein that measures low-grade inflammation and may lead to heart disease, according to a new study.

23 Sep 2004

Evidence pointing to chronic cellular inflammation as the precursor of heart disease and diabetes

Endocrinologists from the University at Buffalo are providing one more link in the growing chain of evidence pointing to chronic cellular inflammation as the precursor of heart disease and diabetes.

21 Sep 2004

Newly completed Chromosome 5 sequence will be a powerful tool for scientists trying to understand human disease

Four years after publicly revealing the official draft human genetic sequence, researchers have reached the halfway point in dotting the i's and crossing the t's of the genetic sentences describing how to build a human.

16 Sep 2004

Missing link between inflammatory markers in the bloodstream and the increased risk of heart attack

The study of 386 Olmsted County, Minn., residents used transesophageal echocardiography (TEE) to obtain high-quality images of the lining of the aorta, the main artery through which the heart pumps blood to the body.

14 Sep 2004

Blacks and whites have similar amounts of coronary calcium deposits, which are a sign of atherosclerotic plaques

In contrast to earlier studies that indicated African-Americans tend to have lower amounts of atherosclerosis than whites, despite having higher cardiovascular death rates, heart scans in a large, representative population indicate that blacks and whites have similar amounts of coronary calcium deposits

1 Sep 2004

Atherosclerosis News and Research

Further Reading

Impaired endothelial function is an early indicator of atherosclerosis

Newly discovered gene could be a significant contributor to diabetes in Americans

Gene variations explain why people with type 2 diabetes are at much greater risk for coronary artery disease

Biomedical engineers receive $11.5 million to study how white blood cells navigate

Study raises important questions about the use of drugs that promote or prevent angiogenesis

Study increases likelihood that MRI could be used as predictive technology to determine which patients should be placed on statin therapy for atherosclerosis

Atheromatosis, which lies behind heart attacks, stroke, and other cardiovascular problems, has a major impact on public health

Low-dose estrogen therapy significantly reduced the progression of fatty buildup in the arteries leading to the heart

Diet high in soy could be good for the hearts and bones of premenopausal women

Lipid profile differences explain why two people with the same overall cholesterol level can have different degrees of cardiovascular disease

Research continues to show the cardiovascular benefits of fish consumption or omega-3 fatty acids

Interleukin-6 has potential as a therapeutic drug in treating metabolic disorders such as obesity, type 2 diabetes and atherosclerosis

Sibling history is a better predictor of coronary heart disease than parental history or traditional risk factor scoring

Clusters of genes within human aortas appear to predict risk for atherosclerosis

Guidant announces plans to initiate vulnerable plaque study

Terror fears raise women's level of protein linked to heart disease

Evidence pointing to chronic cellular inflammation as the precursor of heart disease and diabetes

Newly completed Chromosome 5 sequence will be a powerful tool for scientists trying to understand human disease

Missing link between inflammatory markers in the bloodstream and the increased risk of heart attack

Blacks and whites have similar amounts of coronary calcium deposits, which are a sign of atherosclerotic plaques

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