Colon News and Research

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PKS-positive E. coli may encourage development of colon cancer

Scientists at the University of Liverpool have identified a type of E. coli bacteria that may encourage the development of colon cancer.

17 Aug 2012

Tofacitinib drug shows promise against moderate-to-severe ulcerative colitis

An investigational drug currently under FDA review for the treatment of rheumatoid arthritis has now shown positive results in patients with moderate-to-severe ulcerative colitis, according to researchers at the University of California San Diego, School of Medicine.

16 Aug 2012

Pouch surgery has long-term costs for young patients

Restorative proctocolectomy with ileal pouch-anal anastomosis is associated with high complication rates and poor body image in patients who undergo the procedure at a young age, research shows, with women at additional risk for sexual dysfunction.

15 Aug 2012

New type of medical imaging could help doctors spot tumors more quickly

Scientists from the University of Southern California in Los Angeles and Washington University in St. Louis have developed a new type of medical imaging that gives doctors a new look at live internal organs.

14 Aug 2012

FDA extends PDUFA target action date for review of Santarus' UCERIS NDA

Santarus, Inc. today announced that the U.S. Food and Drug Administration (FDA) has extended the Prescription Drug User Fee Act (PDUFA) target action date for the review of the New Drug Application (NDA) for UCERIS (budesonide) tablets 9 mg for the induction of remission of mild to moderate active ulcerative colitis from October 16, 2012 to January 16, 2013.

14 Aug 2012

New clinical trial to study how worm eggs may relieve symptoms of ulcerative colitis

A new clinical trial designed to study how worm eggs may relieve symptoms of ulcerative colitis (UC) will begin enrolling patients at NYU School of Medicine's Clinical and Translational Science Institute. This unusual therapy has been used in previous clinical trials on patients with inflammatory bowel diseases, but the mechanism of action is unclear.

8 Aug 2012

New class of drugs reduces adverse effects of cellular damage from cancer chemotherapy

Chemotherapy kills tumor cells, but it also wreaks havoc on the rest of the body. A team of researchers led by Igor Roninson of the South Carolina College of Pharmacy just reported the discovery of a new class of drugs that reduces the adverse effects of cellular damage from chemotherapy.

8 Aug 2012

Viewpoints: Mass. at disadvantage in cutting health costs; McDonnell says Va. can point to better way

Massachusetts will be the first state to try to cap overall health care spending, both private and public, so that it will grow no faster than the state economy. The state was able to reach near-universal coverage because the vast majority of its population was already covered by some form of insurance. It also could subsidize coverage for the uninsured using a big pool of money that had been used for charity care. But when it comes to controlling health care costs, Massachusetts has no advantage, and in fact is starting behind most other states.

7 Aug 2012

Rexahn announces completion of RX-3117 exploratory Phase I clinical trial in cancer patients

Rexahn Pharmaceuticals, Inc., a clinical stage pharmaceutical company commercializing potential best in class oncology and CNS therapeutics, today announced that it has completed its exploratory Phase I clinical trial of RX-3117 in cancer patients.

6 Aug 2012

Scientists identify key factor that drives resistance to cancer drug

Developing resistance to chemotherapy is a nearly universal, ultimately lethal consequence for cancer patients with solid tumors - such as those of the breast, prostate, lung and colon - that have metastasized, or spread, throughout the body. A team of scientists led by Fred Hutchinson Cancer Research Center has discovered a key factor that drives this drug resistance - information that ultimately may be used to improve the effectiveness of therapy and buy precious time for patients with advanced cancer.

6 Aug 2012

Longer looks: Mississippi learns from Iran's health care system

Sabrina Seeling seemed too young to die. ... One night she stayed up all night translating a Latin text into English for a college paper. ... During the all-nighter, Ms. Seelig took Ephedra, a stimulant diet drug that had been banned by the Food and Drug Administration three years earlier, and had a few beers. ... When she felt sick, she called Poison Control for help, and spoke very clearly, a recording of the call shows.

3 Aug 2012

HSF1 increases expression of chaperones and supports cancer metastasis

Whitehead Institute researchers have found that increased expression of a specific set of genes is strongly associated with metastasis and death in patients with breast, colon, and lung cancers.

3 Aug 2012

Emergency diverticulitis surgery victim of the ‘weekend effect’

Patients who have emergency surgery at weekends for acute diverticulitis have worse outcomes than those admitted on weekdays, the results of a US study show.

2 Aug 2012

Researchers report one-third cut in the rate of lethal SSIs after colorectal operations

A patient safety team including researchers in the Johns Hopkins Armstrong Institute for Patient Safety and Quality reported a one-third cut in the rate of costly and potentially lethal surgical site infections (SSIs) following colorectal operations after requiring use of a simple safety checklist and urging caregivers to speak up if they see potentially unsafe practices.

2 Aug 2012

Scientists discover critical molecular switch that regulates autophagy

The body has a built-in system known as autophagy, or 'self-eating,' that controls how cells live or die. Deregulation of autophagy is linked to the development of human diseases, including neural degeneration and cancer.

2 Aug 2012

Researchers discover new approach to treat two lethal metastatic cancers

A potentially powerful new approach to treating two lethal metastatic cancers - triple negative breast cancer and clear cell renal cell carcinoma, the most common form of kidney cancer - has been discovered by researchers at Mayo Clinic in Florida.

1 Aug 2012

KSU researcher completes study that examines dietary fiber in children

Experts have long since determined the recommended daily amounts of certain nutrients, such as calcium and vitamin D, but the numbers for nutrients like fiber have proven more difficult to nail down.

31 Jul 2012

Combined approach reduces SSIs by 33% in patients after colorectal procedures

A surgical patient safety program that combines three components-accurate outcome measurement, support of hospital leadership, and engaged frontline providers-reduces surgical site infections (SSIs) by 33 percent in patients who undergo colorectal procedures, according to a new study published in the August issue of the Journal of the American College of Surgeons.

30 Jul 2012

Lack of physical activity and life expectancy: an interview with Dr I-Min Lee

With the approach of the Olympic Games, a group of researchers throughout the world thought that it would be a good time to draw the attention of the world to the health dangers of being physically inactive.

30 Jul 2012

MASL protein from plant's seeds may halt spread of melanoma

An international team of scientists led by Gary Goldberg, PhD, of the University of Medicine and Dentistry of New Jersey-School of Osteopathic Medicine (UMDNJ-SOM), has found that a protein from the seeds of a plant used for centuries in traditional medicines may be able to halt the spread of melanoma, a lethal form of skin cancer.

25 Jul 2012