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Mechanistic insights into engineered ACE2 receptor traps

Researchers determined the cryo-electron microscopic (cryo-EM) structures of engineered angiotensin-converting enzyme 2 (ACE2) receptor traps.

12 Aug 2022

Bispecific antibody exhibits high breadth and potency against SARS-CoV-2 Omicron sub-lineages

In a new study, researchers developed bispecific-antibodies (bsAbs) against SARS-CoV-2 Omicron sub-lineages.

12 Aug 2022

What is the genomic diversity of SARS-CoV-2 infections in households?

In a new study, researchers assessed the genomic diversity of SARS-CoV-2 in households.

12 Aug 2022

People with blood-related cancers more likely to experience COVID breakthrough infections

Individuals with blood-related cancers are more likely to experience a COVID-19 infection even after being vaccinated, a University of Kansas Cancer Center study has found.

12 Aug 2022

Influence of SARS-CoV-2 breakthrough infection and age on humoral immunity post-three-dose COVID-19 vaccination

In a new study, researchers briefly reported the effect of SARS-CoV-2 breakthrough infection and age on humoral immunity following triple-dose SARS-CoV-2 messenger ribonucleic acid (mRNA) vaccination.

12 Aug 2022

What are the unique traits of Long COVID?

In a new study, researchers identified distinctive characteristics of post-acute sequelae of COVID-19 (PASC) via immune profiling.

12 Aug 2022

What is the impact of COVID-19 on male reproductive health?

In a recent study, researchers assessed male reproductive health three months after COVID-19 infection.

12 Aug 2022

Depression may be the strongest predictor of COVID-19-associated persistent brain fog, study finds

In a new study, researchers assessed the prevalence of cognitive complaints in COVID-19 patients and explored the factors associated with brain fog after one year of COVID-19 diagnosis.

12 Aug 2022

How is artificial intelligence used in COVID-19 research?

A new study discussed the roles of artificial intelligence (AI) in combating the COVID-19 pandemic.

12 Aug 2022

Experts urge FDA to include T cell responses when evaluating COVID vaccines

Now, a group of prominent scientists and physicians are urging the FDA to include in its guidance to vaccine developers a recommendation for T-cell assessment in COVID-19 vaccine clinical trials to more comprehensively measure immune response.

11 Aug 2022

How does COVID-19 increase clotting risk?

An in-depth review article describing coronavirus disease 2019 (COVID-19)-related coagulopathy has recently been published in the journal Nature Reviews Immunology.

11 Aug 2022

Study highlights the urgent need for combinatorial drug therapies for SARS-CoV-2

Researchers investigated the susceptibility of naturally-occurring severe acute respiratory syndrome coronavirus 2 main protease variants to protease inhibitor drugs, including nirmatrelvir and ensitrelvir.

11 Aug 2022

Recombination most often occurs on the COVID-19 phylogenetic tree in the form of 'long branches'

An analysis of millions of SARS-CoV-2 genomes finds that recombination of the virus is uncommon, but when it occurs, it is most often in the spike protein region, the area which allows the virus to attach to and infect host cells.

11 Aug 2022

Assessment of replicon ribonucleic acid COVID-19 vaccine in nonhuman primates

Researchers explored the immunogenicity of a replicon ribonucleic acid (repRNA) COVID-19 vaccine, repRNA-CoV2S, in pigtail macaques.

11 Aug 2022

Study identifies multiple pathways adopted by SARS-CoV-2 to develop resistance to nirmatrelvir

Researchers demonstrated multiple routes SARS-CoV-2 might take to develop high-level resistance to nirmatrelvir, an oral antiviral targeting the 3C-like protease (3CLpro) of SARS-CoV-2.

11 Aug 2022

Gut microbial and immune parameters linked to heterogeneous inter-personal COVID-19 vaccine-triggered immunity

A new study identified the gut microbial and immune variables linked to heterogeneous messenger ribonucleic acid (mRNA) COVID-19 vaccine responses between individuals.

11 Aug 2022

SARS-CoV-2 receptor-binding domain-based protein subunit vaccine shows promise against multiple SARS-CoV-2 variants

Researchers described a novel protein subunit vaccine comprising the receptor-binding domain (RBD) of ancestral SARS-CoV-2 spike (S) protein, dimerized with an immunoglobulin (Ig)G1-fraction, crystallizable (Fc) domain.

11 Aug 2022

How did the COVID-19 pandemic impact the epidemiology of antibiotic resistant bacteria?

In an article, a mathematical model was used to explore how behavioral responses to the COVID-19 pandemic impact the anti-microbial resistance across communities.

11 Aug 2022

Azelastine nasal spray could decrease SARS-CoV-2 load

A new study illustrated that early azelastine nasal spray therapy might lower the SARS-CoV-2 load among virus-infected patients.

11 Aug 2022

Nanoparticle-based lateral flow immunoassay for the detection of anti-SARS-CoV-2 neutralizing antibodies

In a recent Biomaterials study, researchers developed AIEgen-embedded polystyrene (PS) nanoparticles-based LFIA that can accurately detect anti-SARS-CoV-2 NAb in serum samples of vaccinated individuals.

11 Aug 2022

SARS News and Research

Mechanistic insights into engineered ACE2 receptor traps

Bispecific antibody exhibits high breadth and potency against SARS-CoV-2 Omicron sub-lineages

What is the genomic diversity of SARS-CoV-2 infections in households?

People with blood-related cancers more likely to experience COVID breakthrough infections

Influence of SARS-CoV-2 breakthrough infection and age on humoral immunity post-three-dose COVID-19 vaccination

What are the unique traits of Long COVID?

What is the impact of COVID-19 on male reproductive health?

Depression may be the strongest predictor of COVID-19-associated persistent brain fog, study finds

How is artificial intelligence used in COVID-19 research?

Experts urge FDA to include T cell responses when evaluating COVID vaccines

How does COVID-19 increase clotting risk?

Study highlights the urgent need for combinatorial drug therapies for SARS-CoV-2

Recombination most often occurs on the COVID-19 phylogenetic tree in the form of 'long branches'

Assessment of replicon ribonucleic acid COVID-19 vaccine in nonhuman primates

Study identifies multiple pathways adopted by SARS-CoV-2 to develop resistance to nirmatrelvir

Gut microbial and immune parameters linked to heterogeneous inter-personal COVID-19 vaccine-triggered immunity

SARS-CoV-2 receptor-binding domain-based protein subunit vaccine shows promise against multiple SARS-CoV-2 variants

How did the COVID-19 pandemic impact the epidemiology of antibiotic resistant bacteria?

Azelastine nasal spray could decrease SARS-CoV-2 load

Nanoparticle-based lateral flow immunoassay for the detection of anti-SARS-CoV-2 neutralizing antibodies

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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