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Combination produces more proliferative, enduring central memory T cells for cellular therapy

Treating T cells harvested from a patient with a combination of an epigenetic drug and a cytokine while expanding the cells in the lab re-programs them into a stronger T cell type that persists longer than its comrades, researchers at The University of Texas MD Anderson Cancer Center report in Cancer Immunology Research, a journal of the American Association for Cancer Research.

25 Mar 2020

Celltrion announces key milestones in its efforts to fight COVID-19

Celltrion Group today announced key milestones in its efforts to fight the 2019 novel coronavirus (COVID-19) pandemic.

23 Mar 2020

CAR macrophages can be used to effectively fight solid tumors

Chimeric antigen receptor (CAR) T cell therapy has been a game-changer for blood cancers but has faced challenges in targeting solid tumors.

23 Mar 2020

African-American men less likely to use more targeted biopsy option for prostate cancer

Researchers at the University of Cincinnati have found in a retrospective study that African-American men are less likely to use a more targeted biopsy option for prostate cancer, despite an increased incidence in this group of patients.

17 Mar 2020

Researchers elucidate new mechanism for controlling DNA methylation in cells

Why normal cells turn into cancer cells One of the factors is deeply related to the failure of the cell differentiation mechanism called DNA methylation.

17 Mar 2020

Max Planck researchers identify mechanistic basis of antigen receptor gene assembly

Adaptive immunity is a powerful defense mechanism in vertebrates. A finely tuned interplay of different cell types provides a pathogen-specific immune response to eliminate for example bacteria and viruses.

13 Mar 2020

Researchers develop a microfluidic chip to help detect prostate cancer

Researchers of Sechenov University together with their colleagues from Australia used the microfluidics technology to develop a device able to isolate cancer cells from urine of patients with prostate cancer.

10 Mar 2020

Research introduces a new concept of resectability in pancreatic cancer

Pancreatic cancer is predicted to become the second leading cause of cancer-related deaths by 2030. However, recent developments in staging and treatment provide options to improve the long-term survival rate for an otherwise devastating diagnosis.

10 Mar 2020

NCCN publishes recommendations for assessing quality improvements in cancer care

The National Comprehensive Cancer Network has published a curated list of high-impact measures for assessing quality improvements in cancer care.

10 Mar 2020

Levels of sBTLA proteins may be a marker of overall survival in patients with HCC

In the 2020 February 25 issue of Scientific Reports, a research group from the Department of Hepatology in Osaka City University Graduate School of Medicine, Japan reported that levels of a circulating soluble immune checkpoint protein can be used as a potential marker to predict overall survival in patients with advanced HCC.

9 Mar 2020

Investigational CAR-T therapy for Hodgkin lymphoma receives fast-track designation from FDA

Based on proof-of-concept results from clinical trials at University of North Carolina Lineberger Comprehensive Cancer Center and Baylor College of Medicine, an investigational cellular immunotherapy for Hodgkin lymphoma has received a Regenerative Medicine Advanced Therapy designation from the U.S. Food and Drug Administration.

9 Mar 2020

New 'Immuno-Engineering to Improve Immunotherapy' Center formed to advance cancer therapy

Harvard University's Wyss Institute of Biologically Inspired Engineering and its collaborating institutions, the Harvard John A. Paulson School of Engineering and Applied Sciences, Dana-Farber Cancer Institute, and Harvard's Department of Stem Cell and Regenerative Biology, announce the formation of a new NIH-funded Immuno-Engineering to Improve Immunotherapy Center.

7 Mar 2020

Antidepressant shows promise in helping men with recurrent prostate cancer

An antidepressant in use for decades, repurposed to fight prostate cancer, shows promise in helping patients whose disease has returned following surgery or radiation, a pilot study at USC shows.

4 Mar 2020

Clinical factors during pregnancy associated with congenital CMV infection in newborns

A group led by researchers from Kobe University has illuminated clinical factors that are related to the occurrence of congenital cytomegalovirus infection in newborns.

28 Feb 2020

Johns Hopkins researchers make progress in the development of noninvasive urine test for prostate cancer

Researchers at the Johns Hopkins Kimmel Cancer Center have made significant progress toward development of a simple, noninvasive liquid biopsy test that detects prostate cancer from RNA and other specific metabolic chemicals in the urine.

28 Feb 2020

Researchers elucidate structure and function of enzyme that builds complex sugar trees

Researchers have used cryo-electron microscopy to elucidate for the first time the structure and function of a very small enzyme embedded in cell membranes.

27 Feb 2020

Advanced hollow nanomaterials can be used to create biosensors for early cancer detection

For the first time, a team of scientists at the University of Central Florida has created functional nanomaterials with hollow interiors that can be used to create highly sensitive biosensors for early cancer detection.

26 Feb 2020

Guiding nanoparticles directly to the tumor cells

Modern anticancer therapies aim to attack tumor cells while sparing healthy tissue. An interdisciplinary team of researchers at Helmholtz-Zentrum Dresden-Rossendorf and FU Berlin has made important progress in this area: the scientists have produced tiny nanoparticles that are designed to specifically target cancer cells.

24 Feb 2020

Scientific breakthrough provides insights into basic mechanisms of allergic reactions

An international research team has been able to describe the overall structure of the antibody type IgE, which is the key molecule in allergic diseases.

24 Feb 2020

UCI makes tremendous strides in prevention, early detection and treatment of cancer

Like most people, John Gifford wasn't looking forward to a colonoscopy when he arrived on the UCI Medical Center campus in Orange in 2018.

23 Feb 2020

Antigen News and Research

Combination produces more proliferative, enduring central memory T cells for cellular therapy

Celltrion announces key milestones in its efforts to fight COVID-19

CAR macrophages can be used to effectively fight solid tumors

African-American men less likely to use more targeted biopsy option for prostate cancer

Researchers elucidate new mechanism for controlling DNA methylation in cells

Max Planck researchers identify mechanistic basis of antigen receptor gene assembly

Researchers develop a microfluidic chip to help detect prostate cancer

Research introduces a new concept of resectability in pancreatic cancer

NCCN publishes recommendations for assessing quality improvements in cancer care

Levels of sBTLA proteins may be a marker of overall survival in patients with HCC

Investigational CAR-T therapy for Hodgkin lymphoma receives fast-track designation from FDA

New 'Immuno-Engineering to Improve Immunotherapy' Center formed to advance cancer therapy

Antidepressant shows promise in helping men with recurrent prostate cancer

Clinical factors during pregnancy associated with congenital CMV infection in newborns

Johns Hopkins researchers make progress in the development of noninvasive urine test for prostate cancer

Researchers elucidate structure and function of enzyme that builds complex sugar trees

Advanced hollow nanomaterials can be used to create biosensors for early cancer detection

Guiding nanoparticles directly to the tumor cells

Scientific breakthrough provides insights into basic mechanisms of allergic reactions

UCI makes tremendous strides in prevention, early detection and treatment of cancer

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