Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Genetic findings may offer clues to accurate diagnosis and treatment of type 1.5 diabetes

Researchers investigating a form of adult-onset diabetes that shares features with the two better-known types of diabetes have discovered genetic influences that may offer clues to more accurate diagnosis and treatment.

4 May 2017

New drug mimics health effects of exercise, say researchers

Scientists have managed to mimic the health effects of exercise in mice, simply by using a pill, according to a study published in Cell Metabolism. The drug activated a genetic pathway that is triggered by running, which led mice to burn off more fat and increase their stamina levels, despite them being sedentary.

4 May 2017

Breakthrough therapy reduces symptoms of Graves' eye disease in clinical trials

The disease is characterized by inflammation and a buildup of tissue around the eyes that cause them to bulge painfully from their sockets.

4 May 2017

New review explains how calorie restriction can extend life

A new review proposes a theory to explain how calorie restriction can extend life across a variety of species.

3 May 2017

Moderate cardiorespiratory fitness can protect from fatty liver

According to a new Finnish study, cardiorespiratory fitness is inversely related to risk of fatty liver. The research was conducted at the University of Turku, Finland, and shows that, despite the person's weight, achieving moderate cardiorespiratory fitness can protect from fatty liver.

3 May 2017

Impaired effects of insulin can increase cancer risk, shows study

Over the decades, scientists have repeatedly shown that patients with increased levels of the hormone insulin in their blood can experience increased risks of cancer. Surprisingly, however, Joslin Diabetes Center researchers now have discovered that impaired effects of insulin also can boost these risks.

3 May 2017

Research sheds new light on surprising link between blood sugar and brain cancers

New research further illuminates the surprising relationship between blood sugar and brain tumors and could begin to shed light on how certain cancers develop.

3 May 2017

UC San Diego researchers identify pathways that regulate pancreatic beta cell growth

Pancreatic beta cells help maintain normal blood glucose levels by producing the hormone insulin -- the master regulator of energy (glucose). Impairment and the loss of beta cells interrupts insulin production, leading to type 1 and 2 diabetes.

2 May 2017

Avocado consumption linked to higher intake of essential nutrients, better diet quality

A new analysis of the National Health and Nutrition Examination Survey data, compared avocado consumers to non-consumers and found that consuming avocados may be associated with an overall better diet, higher intake of essential nutrients, lower body weight, lower Body Mass Index and smaller waist circumference.

2 May 2017

Takeda announces accelerated approval from FDA for new lung cancer treatment

Takeda Pharmaceutical Company Limited (TSE: 4502) today announced that ALUNBRIG (brigatinib) has received Accelerated Approval from the U.S. Food and Drug Administration for the treatment of patients with anaplastic lymphoma kinase-positive (ALK+) metastatic non-small cell lung cancer who have progressed on or are intolerant to crizotinib.

28 Apr 2017

Study: Artificial pancreas helps young children better control their diabetes

A pilot study among young children with Type 1 diabetes found that a University of Virginia-developed artificial pancreas helped study participants better control their condition.

28 Apr 2017

Scientists rewire mouse stem cells to fight inflammation caused by arthritis

Using new gene-editing technology, researchers have rewired mouse stem cells to fight inflammation caused by arthritis and other chronic conditions.

28 Apr 2017

Marijuana use among pregnant women linked to low birth weight infants

In a new study, researchers in London, Ontario found that women who used marijuana while pregnant were almost three times more likely to have an infant with low birth weight than women who did not use marijuana.

27 Apr 2017

Exposure to variable temperatures may have positive effect on health

Exposure to environments outside a comfortable temperature could help tackle major metabolic diseases, such as diabetes and obesity, and should be reflected in modern building practices, finds a study published today.

26 Apr 2017

Study reveals promising results for primary liver cancer patients treated with SIR-Spheres Y-90 resin microspheres

Patients with advanced or inoperable Hepatocellular Carcinoma (HCC) who usually received one or two treatments with liver-directed SIR-Spheres Y-90 resin microspheres in the 459-patient French SARAH study had similar survival compared to patients who received standard twice-daily systemic treatment with sorafenib, but with less than half the number and significantly fewer severe treatment-related adverse effects and significantly better Quality of Life, according to data presented here at The International Liver Congress™ 2017.

26 Apr 2017

Vitamin A combined with high-fat diet may lead to increased risk for obesity and diabetes

Vitamin A is an essential nutrient that the human body needs to function properly. But new research presented today at the American Physiological Society annual meeting at Experimental Biology 2017 in Chicago suggests that normal levels of vitamin A within a high-fat diet can negatively affect expression of liver genes associated with glucose and fat metabolism.

26 Apr 2017

Novel mechanism of antidepressant action may benefit patients unresponsive to SSRI treatment

Antidepressants treat symptoms of depression by increasing levels of brain signaling molecules such as serotonin, as with the most widely used type of antidepressant, selective serotonin reuptake inhibitors.

25 Apr 2017

High-fat diet and obesity drive liver immune cells to promote metabolic syndrome

A high-fat diet and obesity turn "hero" virus-fighting liver immune cells "rogue", leading to insulin resistance, a condition that often results in type 2 diabetes, according to research published today in Science Immunology.

21 Apr 2017

Researchers discover how protein aggregation triggers aging

Not only does our way of life determine how long we live but so too does our genetic material. Of particular importance here is a genetic program that is controlled by the insulin receptor. A team of researchers from the Universities of Cologne and Bonn has now discovered how protein aggregation affects this genetic program and thus triggers aging.

21 Apr 2017

Researchers identify how post-biotics lower blood glucose during obesity

You've heard of pre-biotics and pro-biotics, but now you'll be hearing a lot more about post-biotics. Researchers at McMaster University have begun to identify how post-biotics, or the by-products of bacteria, lower blood glucose and allow insulin to work better.

20 Apr 2017

Insulin News and Research

Further Reading

Genetic findings may offer clues to accurate diagnosis and treatment of type 1.5 diabetes

New drug mimics health effects of exercise, say researchers

Breakthrough therapy reduces symptoms of Graves' eye disease in clinical trials

New review explains how calorie restriction can extend life

Moderate cardiorespiratory fitness can protect from fatty liver

Impaired effects of insulin can increase cancer risk, shows study

Research sheds new light on surprising link between blood sugar and brain cancers

UC San Diego researchers identify pathways that regulate pancreatic beta cell growth

Avocado consumption linked to higher intake of essential nutrients, better diet quality

Takeda announces accelerated approval from FDA for new lung cancer treatment

Study: Artificial pancreas helps young children better control their diabetes

Scientists rewire mouse stem cells to fight inflammation caused by arthritis

Marijuana use among pregnant women linked to low birth weight infants

Exposure to variable temperatures may have positive effect on health

Study reveals promising results for primary liver cancer patients treated with SIR-Spheres Y-90 resin microspheres

Vitamin A combined with high-fat diet may lead to increased risk for obesity and diabetes

Novel mechanism of antidepressant action may benefit patients unresponsive to SSRI treatment

High-fat diet and obesity drive liver immune cells to promote metabolic syndrome

Researchers discover how protein aggregation triggers aging

Researchers identify how post-biotics lower blood glucose during obesity

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