Transplant News and Research

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Life-saving bone marrow transplants are not available to all who need them

Bone marrow (hematopoietic stem cell) transplant is a life saving treatment for patients with blood cancer that replaces blood stem cells lost to disease or chemotherapy. However, for each patient to benefit a matching donor must be found to provide the stem cells for transplant.

27 Feb 2015

Many organ transplant surgeons in U.S. experience burnout

Despite saving thousands of lives yearly, nearly half of organ transplant surgeons report a low sense of personal accomplishment and 40% feel emotionally exhausted, according to a national study on transplant surgeon burnout.

27 Feb 2015

HeartWare International's revenue increases 38% to $73.2 million in Q4 2014

HeartWare International, Inc., a leading innovator of less invasive, miniaturized circulatory support technologies that are revolutionizing the treatment of advanced heart failure, today announced revenue of $73.2 million for the fourth quarter ended December 31, 2014, a 38% increase compared to $53.1 million in revenue for the same period of 2013. For the fiscal year 2014, the company generated revenue of $278.4 million, a 34% increase compared to revenue of $207.9 million in 2013.

26 Feb 2015

Emulsifiers can alter gut microbiota composition to induce intestinal inflammation

Emulsifiers, which are added to most processed foods to aid texture and extend shelf life, can alter the gut microbiota composition and localization to induce intestinal inflammation that promotes the development of inflammatory bowel disease and metabolic syndrome, new research shows.

26 Feb 2015

Fat cell transplantation benefits systemic sclerosis patients with non-healing digital ulcers

Digital ulcers (DUs) are a frequent, painful, and quality of life altering complication for patients with systemic sclerosis (SSc), a connective tissue disease causing a progressive loss of small blood vessels and resulting changes in organs and tissues. DUs on the fingertips of SSc patients are slow to heal, if they heal at all, as many are unresponsive to any therapies.

26 Feb 2015

New medical device could revolutionise kidney disease care in the UK

A new medical device which combines nanotechnology with a pregnancy tester could help diagnose and treat the 1 million people in the UK who don’t know they have kidney disease, a new report by the Institution of Mechanical Engineers reveals today.

26 Feb 2015

Three Austrian men undergo bionic hand reconstruction

Three Austrian men have become the first in the world to undergo a new technique called “bionic reconstruction”, enabling them to use a robotic prosthetic hand controlled by their mind, according to new research published in The Lancet.

26 Feb 2015

Diets high in animal proteins can worsen progression of kidney disease

An estimated 26 million people in the United States have chronic kidney disease, which can lead to complete kidney failure. Once the kidneys fail, patients either need to undergo dialysis treatments three times a week or have a kidney transplant to remain alive.

24 Feb 2015

Betaretrovirus may infect patients with primary biliary cirrhosis

In a new study published in Alimentary Pharmacology & Therapeutics, researchers at the University of Alberta's Faculty of Medicine & Dentistry have shown that a betaretrovirus which resembles a mouse mammary tumor virus infects patients with the rare liver disease, primary biliary cirrhosis (PBC).

20 Feb 2015

Targeted nanomedicines could help prevent heart attacks caused by atherosclerosis

Nanometer-sized "drones" that deliver a special type of healing molecule to fat deposits in arteries could become a new way to prevent heart attacks caused by atherosclerosis, according to a study in pre-clinical models by scientists at Brigham and Women's Hospital and Columbia University Medical Center.

19 Feb 2015

Study provides new insights into early events that shape cancer

A study led by researchers from Brigham and Women's Hospital suggests a new way to trace cancer back to its cell type of origin. By leveraging the epigenome maps produced by the Roadmap Epigenomics Program - a resource of data collected from over 100 cell types - the research team found that the unique genetic landscape of a particular tumor could be used to predict that tumor's cell type of origin.

19 Feb 2015

Researchers develop artificial adrenal system in animal model

If the function of the adrenal gland is disturbed it does not produce enough stress-adjusting messengers. The results are serious and cause life-threatening diseases. Under the direction of Prof. Dr. Stefan R. Bornstein of the university hospital Carl Gustav Carus researchers developed an artificial adrenal system together with the medicine Nobel Prize Laureate Prof. Dr. Andrew Schally in an animal model.

19 Feb 2015

SLU researchers halt fatty liver disease in animal model

Doctors believe that up to 30 percent of the U.S. population may have fat accumulation in the liver, known as non-alcoholic fatty liver disease (NAFLD), that can lead to a range of damaging health consequences.

18 Feb 2015

TKI introduction improves French CML patient survival

Real-world study findings from France show the significant impact tyrosine kinase inhibitor treatment has had on the survival of patients with Philadelphia chromosome-positive chronic myeloid leukaemia.

17 Feb 2015

Rutgers patient gets second chance at life following liver transplant

Mati Muñoz is 65 years old - filled with the enthusiastic energy that comes with a second chance at life. A decade ago, says Muñoz, who lives in Woodbridge Township, N.J., her liver was being destroyed by hepatitis C, a viral disease she believes she contracted as a girl in her native Cuba from a poorly sterilized needle used in a medical procedure.

17 Feb 2015

Eight clinical researchers selected as finalists for Outstanding Investigator Award at Cardiology 2015

Pediatric cardiology researchers and clinicians from numerous centers from around the world are gathering at the Cardiology 2015: the 18th Annual Update on Pediatric and Congenital Cardiovascular Disease conference, sponsored by The Children's Hospital of Philadelphia and Phoenix Children's Hospital on Feb. 11 to Feb. 15 in Scottsdale, Ariz.

16 Feb 2015

Study shows that plant-based vegan diet may lower heart disease risk in obese children

Obese children who begin a low-fat, plant-based vegan diet may lower their risk of heart disease through improvements in their weight, blood pressure, body mass index, cholesterol levels, insulin sensitivity, and high-sensitivity C-reactive, according to Cleveland Clinic research published online today by The Journal of Pediatrics.

16 Feb 2015

Jazz Pharmaceuticals to present defibrotide results for hepatic VOD at BMT Tandem meetings

Jazz Pharmaceuticals plc announced today that researchers will present data on the use of defibrotide, an investigational medicine being studied in the United States (U.S.) for the treatment of hepatic veno-occlusive disease (VOD), a rare, potentially life-threatening, early complication in patients undergoing hematopoietic stem-cell transplantation (HSCT) therapy.

13 Feb 2015

Gift of Hope Organ & Tissue Donor Network saves record number of lives in 2014

February 14th is National Donor Day. To celebrate, Gift of Hope Organ & Tissue Donor Network announced a record number of lives saved by helping 334 donors and their families donate 1,020 organs to patients waiting for a transplant, giving them a second chance at life last year.

13 Feb 2015

Biotech experts to establish ethical guidelines in cellular biotechnology at BEINGS 2015

In May 2015 Atlanta will host Biotechnology and the Ethical Imagination: A Global Summit (BEINGS), an international summit drawing together the world's thought leaders on the highly debated issues of cellular biotechnology.

13 Feb 2015