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Russian scientists explain how an additional component can triple vaccine efficiency

A team of Russian scientists carried out a study on the cell immunity level and found out how an adjuvant called azoximer bromide increases the immunogenicity of the anti-flu vaccine.

12 Nov 2019

Juvenile immune arthritis – new treatments wanted

Juvenile immune arthritis (JIA) is a severely undertreated condition, and new medications are badly needed to relieve the signs and symptoms of the illness, according to a new study presented at the 2019 ACR/ARP Annual Meeting.

11 Nov 2019

New textbook on mysterious and deadly cytokine storm syndrome

There's no telling where the call will come from, or when. But Randy Cron, M.D., Ph.D., professor of pediatrics and medicine at UAB, knows to expect them.

11 Nov 2019

Clinical benefit of anticoagulants for atrial fibrillation decreases with age, shows study

The net clinical benefit of anticoagulants for atrial fibrillation (AF) -- one of the most important causes of irregular heartbeats and a leading cause of stroke -- decreases with age, as the risk of death from other factors diminishes their benefit in older patients, according to a study led by researchers at UC San Francisco.

11 Nov 2019

UM launches CAR-T clinical trial for patients with myasthenia gravis

Neuromuscular experts with the University of Miami Health System and the Miller School of Medicine will launch a Phase 1/2 clinical trial (NCT04146051) using the CAR-T drug, Descartes-08, to treat patients with generalized myasthenia gravis.

5 Nov 2019

Penn researchers tag CAR T cells with imaging markers to monitor cancer therapy

With CAR T cell therapy, a patient's own immune cells are genetically modified and inserted back into the body to find and kill cancer. This form of immunotherapy has already revolutionized some cancer treatments, but once the CAR T cells are inside a patient, where do they go? How do doctors know that they have successfully reached their target and that they are continuing to fight disease weeks, months, or even years later?

5 Nov 2019

MD Anderson and Takeda announce agreement to develop off-the-shelf CAR NK-cell therapy platform

The University of Texas MD Anderson Cancer Center and Takeda Pharmaceutical Company Limited today announced an exclusive license agreement and research agreement to develop cord blood-derived chimeric antigen receptor-directed natural killer (CAR NK)-cell therapies, 'armored' with IL-15, for the treatment of B-cell malignancies and other cancers.

5 Nov 2019

Researchers develop new type of transposase protein with improved biochemical properties

The team, comprising researchers from the European Molecular Biology Laboratory, the Universitätsklinikum Würzburg and the Paul-Ehrlich-Institut, managed to design a new variant of the Sleeping Beauty transposase with dramatically improved biochemical properties.

4 Nov 2019

Popular health campaigns aren’t always the most productive, says new study

Researchers have found that just because a public health campaign is popular among the digital community, it doesn’t mean it will produce gains in healthy behavior. This study, published in Lancet Oncology, concludes that in addition to attractive slogans or easy-to-understand captions and images, the relevance of the focused health issue to the target audience and to current guidelines may guide audience behavior.

31 Oct 2019

UCLA prostate cancer program receives $8.7 million grant from NCI

The prostate cancer program at the UCLA Jonsson Comprehensive Cancer Center and UCLA Health has been awarded an $8.7 million Specialized Program of Research Excellence, or SPORE, grant from the National Cancer Institute.

31 Oct 2019

Mount Sinai hosts Fourth Annual Prostate Cancer Research Gala

The Department of Urology at the Icahn School of Medicine at Mount Sinai will host its Fourth Annual Prostate Cancer Research Gala on Wednesday, November 6, at Cipriani 42nd Street.

31 Oct 2019

Internet popularity of health awareness campaigns may not always inspire action

A new study published in Lancet Oncology reveals that the internet popularity of health awareness campaigns may not always translate into a greater interest in related health behaviors.

31 Oct 2019

Multi-centre registry trial tests use of PSMA tracer for early detection of prostate cancer

Led by researchers at Lawson Health Research Institute, a multi-centre registry trial is testing the use of a new imaging tracer, called a PSMA tracer, for early detection of recurrent prostate cancer. The registry gives patients access to a new type of imaging and will assess the impact on patient care.

30 Oct 2019

Novel antibodies could provide a universal flu vaccine

Now, a new study published in the journal Science on October 25, 2019, reports on a set of three novel antibodies that bind to another type of viral cell surface antigen called neuraminidase (NA) that is necessary for viral replication.

28 Oct 2019

3D-printed cell traps help researchers remove the hay to expose cancer cells

Finding a handful of cancer cells hiding among billions of blood cells in a patient sample can be like finding a needle in a haystack. In a new approach enabled by 3D-printed cell traps, researchers are removing the hay to expose the cancer cells.

28 Oct 2019

New cellular immunotherapy for cancers

A new study published in the journal Nature Communications on 22 October 2019 reports a new approach to cancer treatment that increases the immune capability of T lymphocytes against malignant cancers. This allows the T cells to successfully infiltrate and destroy these tumors. Animal trials have been completed and the researchers are planning clinical trials in human beings next.

26 Oct 2019

Phase 2 clinical trial of CAR T-cell therapy starts at Atlantic Health System

Atlantic Health System is treating patients in a new Phase 2 clinical trial of CAR T-cell therapy at Morristown Medical Center. A select number of sites across the U.S. are involved in this study, which is done on an outpatient basis.

25 Oct 2019

Cooperative research center at LLNL aims to develop vaccines for chlamydia

A cooperative research center that aims to develop vaccines for chlamydia has been established by the National Institutes of Health at Lawrence Livermore National Laboratory.

24 Oct 2019

Disrupting key immune regulator boosts anti-tumor immunity, enables cancer clearance

The immune system must strike an exquisite balance between vanquishing infections and cancer, while at the same time restraining its activity to avoid inadvertently attacking the body's healthy tissues and organs.

23 Oct 2019

Celiac disease may now be curable with biodegradable nanoparticles

A phase 2 trial just concluded shows that people with celiac disease may now be able to hope for a cure, through a treatment that makes the immune system tolerant towards gluten. This could eventually make it possible for such individuals to eat gluten-containing foods without fear.

22 Oct 2019

Antigen News and Research

Russian scientists explain how an additional component can triple vaccine efficiency

Juvenile immune arthritis – new treatments wanted

New textbook on mysterious and deadly cytokine storm syndrome

Clinical benefit of anticoagulants for atrial fibrillation decreases with age, shows study

UM launches CAR-T clinical trial for patients with myasthenia gravis

Penn researchers tag CAR T cells with imaging markers to monitor cancer therapy

MD Anderson and Takeda announce agreement to develop off-the-shelf CAR NK-cell therapy platform

Researchers develop new type of transposase protein with improved biochemical properties

Popular health campaigns aren’t always the most productive, says new study

UCLA prostate cancer program receives $8.7 million grant from NCI

Mount Sinai hosts Fourth Annual Prostate Cancer Research Gala

Internet popularity of health awareness campaigns may not always inspire action

Multi-centre registry trial tests use of PSMA tracer for early detection of prostate cancer

Novel antibodies could provide a universal flu vaccine

3D-printed cell traps help researchers remove the hay to expose cancer cells

New cellular immunotherapy for cancers

Phase 2 clinical trial of CAR T-cell therapy starts at Atlantic Health System

Cooperative research center at LLNL aims to develop vaccines for chlamydia

Disrupting key immune regulator boosts anti-tumor immunity, enables cancer clearance

Celiac disease may now be curable with biodegradable nanoparticles

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