Immune System News and Research

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UCLA research points the way towards a longer-lasting COVID vaccine

Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have identified rare, naturally occurring T cells that are capable of targeting a protein found in SARS-CoV-2 and a range of other coronaviruses.

11 Dec 2021

Potentially serious side effect reported after CAR-T cell therapy for multiple myeloma

Mount Sinai scientists have become the first to report a potentially serious side effect related to a new form of immunotherapy known as CAR-T cell therapy, which was recently approved for the treatment of multiple myeloma.

11 Dec 2021

Indication of minor added benefit of nivolumab for adjuvant treatment of esophageal cancer

In an early benefit assessment, the German Institute for Quality and Efficiency in Health Care investigated whether nivolumab has an added benefit over watchful waiting in the adjuvant treatment of adults with carcinoma of the esophagus or the gastroesophageal junction and pathological residual disease after prior neoadjuvant chemoradiotherapy (CRT).

10 Dec 2021

Impact of mRNA-1273 vaccination during early pregnancy

Researchers from Yale University School of Medicine found that vaccination during the first trimester does not produce congenital disabilities or size abnormalities.

10 Dec 2021

Insight into immune cell communication may pave the way for new cancer vaccines

In the past decade, immunotherapy has helped save the lives of many cancer patients, many with lung cancer, who might have otherwise faced almost certain death sentences.

9 Dec 2021

Analysis finds substantially more mutations in the omicron SARS-CoV-2 variant

A University of Florida Health researcher has successfully analyzed the many mutations in the omicron variant of the SARS-CoV-2 virus, a crucial step in better understanding the variant's potential threat and ways to combat it.

9 Dec 2021

Investigational mRNA-based HIV vaccine shows promise in mice and non-human primates

An experimental HIV vaccine based on mRNA—the same platform technology used in two highly effective COVID-19 vaccines—shows promise in mice and non-human primates, according to scientists at the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

9 Dec 2021

Study reveals the role of intracellular receptor PQBP1 in response to Tau protein

Just as a home security system can alert a homeowner to the presence of an intruder, a protein called polyglutamine binding protein-1 (PQBP1) found in brain cells can alert the body to the presence of "intruding" viruses like human immunodeficiency virus (HIV).

9 Dec 2021

Potential association between senescence and aging in COVID-19

A review published in Cells discussed characteristics of cellular senescence and its potential role in COVID-19.

9 Dec 2021

UEA researchers reveal how immune cells use the body’s fat stores to fight infection

New research from the University of East Anglia and Quadram Institute reveals how our immune cells use the body’s fat stores to fight infection.

9 Dec 2021

Positive results from Phase 3 study of Medicago’s plant-based COVID-19 vaccine candidate announced

Medicago, a biopharmaceutical company headquartered in Quebec City, and GlaxoSmithKline today announce positive efficacy and safety results from the global Phase 3 placebo-controlled efficacy study of Medicago’s plant-based COVID-19 vaccine candidate in combination with GSK’s pandemic adjuvant, conducted in over 24,000 subjects, adults 18 years and above, across six countries.

9 Dec 2021

UVA researchers uncover common link between lupus and macular degeneration

University of Virginia School of Medicine researchers have made a discovery linking lupus, a potentially debilitating autoimmune disorder, and macular degeneration, a leading cause of blindness.

9 Dec 2021

Systemic sclerosis more common among Black children than previously thought

An immune disease that can damage vital organs – and is supposedly rare in young people – is more common than previously thought among Black children, a study suggests.

8 Dec 2021

Study reveals how a protein in the blood is attracted to key component of Adenovirus-based vaccines

A collaborative team from the School of Medicine at the University of Cardiff, Wales and a range of US institutions used the UK's national synchrotron, Diamond Light Source, to help reveal the details of how a protein in the blood is attracted to a key component of Adenovirus based vaccines.

8 Dec 2021

Combination of vaccination and natural infection offers utmost protection against COVID variants

A combination of vaccination and naturally acquired infection appears to boost the production of maximally potent antibodies against the COVID-19 virus, new UCLA research finds.

8 Dec 2021

Epigenetic clocks have potential as biomarkers of COVID-19 vaccine responses

New findings have important implications for research into the impact of COVID-19 and the mRNA vaccination on epigenetic aging in the immune system.

7 Dec 2021

Antibody response to COVID-19 vaccine may be affected by the body’s circadian rhythms

Our internal 24-hour circadian clock regulates many aspects of physiology, including the response to infectious disease and vaccination.

7 Dec 2021

Researchers discover biomarker that could aid in early detection of high risk COVID-19 patients

Led by computational researchers from WEHI, in collaboration with The University of Queensland, Queensland University of Technology and Hospital Marcelino Champagnat in Brazil, the study used advanced spatial transcriptomic techniques to screen for genes associated with excessive inflammation in the lungs, a key indicator of severe COVID-19.

7 Dec 2021

A promising new therapeutic target for kidney disease

Despite nearly two million people dying of acute kidney injury every year, and tens of millions more needing treatment, no effective drug treatment for the condition is available.

7 Dec 2021

Octapharma USA announces FDA approval of cutaquig 16.5% for pediatric PI patients

Octapharma USA today announced the U.S. Food & Drug Administration has approved cutaquig [Immune globulin, Subcutaneous (Human)-hipp, 16.5% Solution] for the treatment of pediatric patients age 2 and older with primary humoral immunodeficiency (PI). The FDA previously approved cutaquig for adults with PI.

7 Dec 2021

Immune System News and Research

UCLA research points the way towards a longer-lasting COVID vaccine

Potentially serious side effect reported after CAR-T cell therapy for multiple myeloma

Indication of minor added benefit of nivolumab for adjuvant treatment of esophageal cancer

Impact of mRNA-1273 vaccination during early pregnancy

Insight into immune cell communication may pave the way for new cancer vaccines

Analysis finds substantially more mutations in the omicron SARS-CoV-2 variant

Investigational mRNA-based HIV vaccine shows promise in mice and non-human primates

Study reveals the role of intracellular receptor PQBP1 in response to Tau protein

Potential association between senescence and aging in COVID-19

UEA researchers reveal how immune cells use the body’s fat stores to fight infection

Positive results from Phase 3 study of Medicago’s plant-based COVID-19 vaccine candidate announced

UVA researchers uncover common link between lupus and macular degeneration

Systemic sclerosis more common among Black children than previously thought

Study reveals how a protein in the blood is attracted to key component of Adenovirus-based vaccines

Combination of vaccination and natural infection offers utmost protection against COVID variants

Epigenetic clocks have potential as biomarkers of COVID-19 vaccine responses

Antibody response to COVID-19 vaccine may be affected by the body’s circadian rhythms

Researchers discover biomarker that could aid in early detection of high risk COVID-19 patients

A promising new therapeutic target for kidney disease

Octapharma USA announces FDA approval of cutaquig 16.5% for pediatric PI patients

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