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Early treatment with interferons could mitigate severe COVID-19 in people with specific genetic factors

Researchers from the National Cancer Institute, part of the National Institutes of Health, and their collaborators have discovered that people of European and African ancestries who were hospitalized for COVID-19 are more likely to carry a particular combination of genetic variants in a gene known as OAS1 than patients with mild disease who were not hospitalized.

14 Jul 2022

Invasive pneumococcal disease among children during the COVID-19 pandemic in England

Researchers demonstrated heightened invasive pneumococcal disease incidence in children younger than 15 during the SARS-CoV-2 pandemic in England.

14 Jul 2022

Antibody signatures strongly associated with SARS-CoV-2 immunopathology identified using a novel B cell epitope discovery method

A recent study discovered antibody footprints strongly correlated with immunopathology of SARS-CoV-2 infection using a new B cell epitope identification approach

14 Jul 2022

Researchers identify fusion peptide-specific monoclonal antibodies with broad neutralizing activity

Neutralizing mAbs identified in the current study sheds light on ACE2-triggered conformational change that restricts the immunogenicity of the highly conserved FP region.

14 Jul 2022

The global succinylation and protein abundance in SARS-CoV-2–infected cells

Researchers assessed the global succinylation of SARS-CoV-2-infected host cells.

14 Jul 2022

The disease burden and clinical severity of the SARS-CoV-2 Omicron BA.2 sublineage outbreak in Shanghai

Researchers estimated the severity and burden of COVID-19 in a recent outbreak in Shanghai, China.

14 Jul 2022

Study finds SARS-CoV-2 transmission in children and adolescents is lower than adults

Researchers observed lower susceptibility of children and adolescents to SARS-CoV-2 infection.

14 Jul 2022

The interaction between SARS-CoV-2 and influenza A during coinfection

Researchers assessed the host response to influenza A and COVID-19 during coinfection.

14 Jul 2022

SARS-Arena reveals conserved parts of viral proteins that cause COVID-19

Vaccines may need to dig a little deeper to stop SARS-CoV-2. Rice University researchers are providing a new shovel.

14 Jul 2022

Study provides detailed understanding of SARS-CoV-2 Omicron sublineage antibody escape

A new study reveals the antibody-mediated neutralization of both current and emerging Omicron subvariants.

13 Jul 2022

GenomeBits representation of SARS-CoV-2 Delta and Omicron genome sequences

In a new study, researchers uncovered distinct genomic features of SARS-CoV-2 Delta and Omicron variants.

13 Jul 2022

Researchers conduct forensic analysis of SARS-CoV-2-related coronaviruses

Researchers conducted a forensic analysis of SARS-CoV-2-related coronaviruses (SARS2r-CoVs).

13 Jul 2022

Evolutionary characteristics of the SARS-CoV-2 Omicron variant

Researchers compared the mutations in the SARS-CoV-2 Omicron variant with others to highlight their evolutionary differences.

13 Jul 2022

New approach could pave the way for development of pan-coronavirus antivirals

To put the COVID-19 pandemic in the rearview mirror and prevent other coronaviruses from causing havoc, the world needs an arsenal of measures to prevent and treat these infections.

13 Jul 2022

Study suggests ZCB11 as a promising antibody drug against all SARS-CoV-2 variants of concern

Researchers at the AIDS Institute, The University of Hong Kong, Department of Microbiology, School of Clinical Medicine, the LKS Faculty of Medicine of The University of Hong Kong and the State Key Laboratory of Emerging Infectious Diseases, HKU, together with structural biologists at The Hong Kong University of Science and Technology, have demonstrated that ZCB11, a broadly neutralizing antibody derived from a local mRNA-vaccinee against the spreading Omicron variants of SARS-CoV-2, displays potent antiviral activities against all variants of concern (VOCs), including the dominantly spreading Omicron BA.1, BA1.1 and BA.2.

13 Jul 2022

Pfizer’s SARS-CoV-2 vaccine does not affect the honeymoon phase of type 1 diabetes

Does high-dose inhaled nitric oxide improve respiratory function and outcomes among pregnant patients hospitalized with severe COVID-19 pneumonia?

Researchers demonstrated that inhaled nitric oxide 200 (iNO200) enhances oxygenation in pregnant COVID-19 patients with severe pneumonia.

13 Jul 2022

SARS News and Research

Early treatment with interferons could mitigate severe COVID-19 in people with specific genetic factors

Invasive pneumococcal disease among children during the COVID-19 pandemic in England

Antibody signatures strongly associated with SARS-CoV-2 immunopathology identified using a novel B cell epitope discovery method

Researchers identify fusion peptide-specific monoclonal antibodies with broad neutralizing activity

The global succinylation and protein abundance in SARS-CoV-2–infected cells

The disease burden and clinical severity of the SARS-CoV-2 Omicron BA.2 sublineage outbreak in Shanghai

Study finds SARS-CoV-2 transmission in children and adolescents is lower than adults

The interaction between SARS-CoV-2 and influenza A during coinfection

SARS-Arena reveals conserved parts of viral proteins that cause COVID-19

Study provides detailed understanding of SARS-CoV-2 Omicron sublineage antibody escape

GenomeBits representation of SARS-CoV-2 Delta and Omicron genome sequences

Researchers conduct forensic analysis of SARS-CoV-2-related coronaviruses

Evolutionary characteristics of the SARS-CoV-2 Omicron variant

New approach could pave the way for development of pan-coronavirus antivirals

Study suggests ZCB11 as a promising antibody drug against all SARS-CoV-2 variants of concern

Pfizer’s SARS-CoV-2 vaccine does not affect the honeymoon phase of type 1 diabetes

The potential of tixagevimab–cilgavimab for treating hospitalized COVID-19 patients

Doggybone DNA COVID-19 vaccine can effectively neutralize SARS-CoV-2 variants

The impact of the SARS-CoV-2 spike A222V mutation on viral infection

Does high-dose inhaled nitric oxide improve respiratory function and outcomes among pregnant patients hospitalized with severe COVID-19 pneumonia?

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