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How lipid metabolites in the gut aid in regulatory T-cell differentiation

Researchers describe the Treg-cell-inducing activity of lipid extracts from the feces of specific-pathogen-free mice.

6 Jun 2023

Severe COVID-19 raises alarm for undiagnosed cancer

Severe SARS-CoV-2 infection is associated with a 1.31 higher risk of being diagnosed with cancer following hospital discharge, particularly renal, hematological, colon, and lung cancers, suggesting a potential link between the infection and undiagnosed cancer.

1 Jun 2023

Mental health profoundly impacts inflammatory responses in the body

Study uncovered mechanisms by which psychological stress affects bowel inflammation.

30 May 2023

Obesity-related cancers take a toll in Southern Africa: Study reveals alarming trends

Research analyzes the prevalence and mortality rates of obesity-related cancers in 16 Southern African countries. It identifies leukemia, esophageal cancer, and colon/rectum cancer as leading causes of cancer mortality in males, and breast cancer, leukemia, and esophageal cancer in females.

29 May 2023

Makeup of microbiome in a person's tumor varies depending on early or late-onset colorectal cancer

Researchers at Georgetown University's Lombardi Comprehensive Cancer Center studied the microbiome of people with colorectal cancer and found the make-up of the bacteria, fungi and viruses in a person's tumor varied significantly depending on whether they were diagnosed with early-onset disease (age 45 or younger) or late-onset disease (age 65 or older).

26 May 2023

Groundbreaking study targets 'jumping genes' in the entire genomes of the human large intestine

The Korea Advanced Institute of Science and Technology (KAIST) and their collaborators have conducted a groundbreaking study targeting 'jumping genes' in the entire genomes of the human large intestine.

25 May 2023

Screening delays during the COVID-19 pandemic likely to increase cancer cases

Delays in cancer screening during the COVID-19 pandemic will likely cause a significant increase in cancer cases that could have been caught earlier with screening, and may now be diagnosed at later stages, placing an increased burden on an already strained healthcare system, according to a new research article published in the Journal of the American College of Surgeons.

25 May 2023

Study could help understand why limiting sugary foods can ease symptoms for IBD patients

Excess sugar hampers cells that renew the colon's lining in a mouse model of inflammatory bowel disease (IBD), according to a new study by University of Pittsburgh scientists.

22 May 2023

Long-term ketogenic diet boosts survival rates in advanced cancer patients

Long-term ketogenic diet shows improved survival rates in cancer patients, with a significantly better overall survival for those following the diet for ≥12 months. Promising results for cancer therapy.

18 May 2023

Unlocking the gut clock: How circadian rhythms and gut microbiota team up to impact human health

Research investigates the connection between circadian rhythms and specific microbial patterns in various disease contexts, emphasizing the need for further studies.

15 May 2023

Metabolically healthy and unhealthy 'forms' of obesity linked with increased risk of obesity-related cancers

New research to be presented at this coming week's European Congress on Obesity in Dublin, Ireland (17-20 May) and published in the Journal of the National Cancer Institute shows that both the metabolically healthy and unhealthy 'forms' of obesity are associated with an increased risk of various obesity-related cancers, with the relationship stronger in metabolically unhealthy obesity.

15 May 2023

Carotenoids' potential in reducing chronic disease risk

Researchers explore the association between the gastrointestinal delivery system and carotenoids.

15 May 2023

Novel ingestible device enables non-invasive profiling of the gut microbiome, proteome, and metabolome

Researchers developed an ingestible device to collect samples from the human intestine.

12 May 2023

New NIH program seeks to discover and catalog the breadth of somatic mosaicism in human tissues

The National Institutes of Health is launching a new program, the Common Fund's Somatic Mosaicism Across Human Tissues Network, that aims to transform our knowledge of how much genetic variation there is in the cells and tissues throughout our bodies.

11 May 2023

Testing policy change could reduce the burden of C. diff infections

A new study published today in the American Journal of Infection Control suggests that allowing bedside nurses to independently order testing for C. difficile significantly decreased the amount of time to receive test results as compared to requiring physician approval.

11 May 2023

What is the association between obesity and insulin resistance in youth and its production of colon-derived acetate, gut-derived hormone secretion, and adipose tissue lipolysis?

Researchers assessed whether insulin resistance and adiposity in youth were linked to the fermentation of dietary fibers.

11 May 2023

Specially designed capsule gives a fuller picture of normal digestion in healthy people

Using a specially designed capsule, researchers can now voyage through the digestive system, collecting new data about digestion and microorganisms.

10 May 2023

Maintaining a healthy weight could reduce future gastrointestinal cancer risk

Doctors have long stressed the importance of maintaining a healthy weight for improving overall health, but a large new study also suggests it could also reduce future gastrointestinal cancer (GI) risk.

10 May 2023

Silenced p16 gene can drive colorectal cancer progression

Colorectal cancer is the fourth most common and second deadliest cancer. How colorectal cancer develops is not well understood, but a team led by researchers at Baylor College of Medicine reports in the Journal of Experimental & Clinical Cancer Research that silencing the gene p16, even though the DNA itself does not change, can drive colorectal cancer progression in animal models.

10 May 2023

Researchers develop new method of encapsulating fecal bacteria to treat serious intestinal infection

Clostridioides difficile infection causes severe diarrhea and results in the death of nearly 20,000 patients in Europe each year. It is one of the most common hospital-acquired infections. When it relapses, the disease must be treated by fecal microbiota transplantation.

10 May 2023

Colon News and Research

How lipid metabolites in the gut aid in regulatory T-cell differentiation

Severe COVID-19 raises alarm for undiagnosed cancer

Mental health profoundly impacts inflammatory responses in the body

Obesity-related cancers take a toll in Southern Africa: Study reveals alarming trends

Makeup of microbiome in a person's tumor varies depending on early or late-onset colorectal cancer

Groundbreaking study targets 'jumping genes' in the entire genomes of the human large intestine

Screening delays during the COVID-19 pandemic likely to increase cancer cases

Study could help understand why limiting sugary foods can ease symptoms for IBD patients

Long-term ketogenic diet boosts survival rates in advanced cancer patients

Unlocking the gut clock: How circadian rhythms and gut microbiota team up to impact human health

Metabolically healthy and unhealthy 'forms' of obesity linked with increased risk of obesity-related cancers

Carotenoids' potential in reducing chronic disease risk

Novel ingestible device enables non-invasive profiling of the gut microbiome, proteome, and metabolome

New NIH program seeks to discover and catalog the breadth of somatic mosaicism in human tissues

Testing policy change could reduce the burden of C. diff infections

What is the association between obesity and insulin resistance in youth and its production of colon-derived acetate, gut-derived hormone secretion, and adipose tissue lipolysis?

Specially designed capsule gives a fuller picture of normal digestion in healthy people

Maintaining a healthy weight could reduce future gastrointestinal cancer risk

Silenced p16 gene can drive colorectal cancer progression

Researchers develop new method of encapsulating fecal bacteria to treat serious intestinal infection

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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