Major Depressive Disorder News and Research

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Major Depressive Disorder (MDD) is a psychiatric condition characterized by depressed mood or anhedonia (significant loss of interest or pleasure). The condition affects more than 15.7 million adults and approximately 3 million adolescents (aged 13 to 17 years) in the USA each year.

Mindfulness meditation training helps prevent major depression

Among primary care patients with subthreshold depression, mindfulness meditation training reduces the incidence of major depression and improves depression symptoms.

13 Mar 2018

Internet-based depression treatment has no long-term protective effect, study shows

The long-term outcome of a randomized controlled trial on depression treated with psychotherapy via internet is presented in the current issue of Psychotherapy and Psychosomatics.

9 Mar 2018

Study investigates use of drugs for the stomach and risk of major depressive disorder

A new study investigating the relationship between one of the commonest type of drugs used for protecting the stomach is presented in the current issue of Psychotherapy and Psychosomatics.

8 Mar 2018

People with MDD feel more negative emotion when remembering painful experiences

People with major depressive disorder (MDD) feel more negative emotion when remembering painful experiences than people without the disorder, according to a new study in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. The study reports that people with MDD were able to control the negative emotions about as well as people unaffected by MDD, but used somewhat different brain circuits to do so.

6 Mar 2018

Levels of inflammatory biomarkers could predict effectiveness of ECT for people with depression

People with major depression that has not been well controlled by medications and who have a biomarker in their blood indicating a higher level of inflammation may benefit more than people with less inflammation from electroconvulsive therapy to ease symptoms of their depression, according to a new UCLA study.

6 Mar 2018

TSRI scientists discover new target for treating major depressive disorder

Scientists on the Florida campus of The Scripps Research Institute have discovered a new target for treating major depressive disorder, a disease that affects more than 16 million American adults.

1 Mar 2018

Novel method to extract valuable psychiatric symptom information from doctors' notes

Researchers at Massachusetts General Hospital and Harvard Medical School have developed a new method to extract valuable symptom information from doctors' notes, allowing them to capture the complexity of psychiatric disorders that is missed by traditional sources of clinical data.

26 Feb 2018

Depression screening by primary care physicians important for adolescents

According to the American Academy of Paediatrics’ new guidelines released this week, all adolescents should undergo a screening for depression annually. The guidelines is published titled, “Guidelines for Adolescent Depression in Primary Care (GLAD-PC): Part I. Practice Preparation, Identification, Assessment, and Initial Management,” by the GLAD-PC Steering group.

26 Feb 2018

People with major depressive disorder have reduced arginine levels, study shows

People suffering from major depressive disorder, MDD, have reduced arginine levels, a new study from the University of Eastern Finland shows. Arginine is an amino acid which the body uses to produce, e.g., nitric oxide.

21 Feb 2018

Study reveals the link between genetic variations and major psychiatric disorders

Psychiatric disorders including schizophrenia, autism, and bipolar disorder share common molecular characteristics, despite variations in gene expression.

9 Feb 2018

Depressive symptoms associated with poorer survival in patients with head and neck cancer

In a study of patients with head and neck cancer, even mild depressive symptoms were associated with poorer overall survival.

22 Jan 2018

Study identifies new target for treatment of depression

According to the World Health Organization more than three hundred million people worldwide are affected by major depressive disorder. Unfortunately, the antidepressants commonly used to treat them only work for 50% of the population.

18 Jan 2018

Research provides insights into mechanisms governing healthy longevity

Keio University Global Research Institute, Tokyo publishes the January 2018 issue of KGRI Research Frontiers that includes researcher video profiles of Keio University researchers and research highlights from high impact publications including 'Regenerative medicine needs collaboration in and out of science in order to face current and future challenges; ‘Does eating fish protect you from depression?’; ‘Insights into the molecular mechanisms leading to kidney dysfunction in diabetic patients’; and ‘Ageing to 100 and beyond: Insights from demographic, phenotypic and genetic studies.

12 Jan 2018

Major Depressive Disorder News and Research

Further Reading

Mindfulness meditation training helps prevent major depression

Internet-based depression treatment has no long-term protective effect, study shows

Study investigates use of drugs for the stomach and risk of major depressive disorder

People with MDD feel more negative emotion when remembering painful experiences

Levels of inflammatory biomarkers could predict effectiveness of ECT for people with depression

TSRI scientists discover new target for treating major depressive disorder

Novel method to extract valuable psychiatric symptom information from doctors' notes

Depression screening by primary care physicians important for adolescents

People with major depressive disorder have reduced arginine levels, study shows

Study reveals the link between genetic variations and major psychiatric disorders

Depressive symptoms associated with poorer survival in patients with head and neck cancer

Study identifies new target for treatment of depression

Research provides insights into mechanisms governing healthy longevity

Metabolic Syndrome could make it harder for older adults to respond to antidepressant therapy

C-Path receives FDA’s clinical outcome assessment qualification for SMDDS

Researchers use new approach to identify casual mechanisms in depression

New method helps measure effect of one brain region on another in depression

New study examines effects of gene variant on resting-state brain function in patients with MDD

Undocumented Mexican immigrants living in the country at risk for mental disorders

New analysis reveals insights into long-term effects of antidepressant drugs

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