Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Chemical modification improves release and availability of insulin, research shows

Replacing a hydrogen atom by an iodine atom in insulin, the hormone retains its efficacy but is available more rapidly to the organism.

3 Jan 2017

AMPK enzyme plays vital role in enhancing muscle insulin sensitivity after physical activity

ampk Physical activity benefits diabetics and others with insulin resistance. One of the reasons is that a single bout of physical activity increases the effectiveness of insulin.

3 Jan 2017

Diabetes can be prevented and reversed with carbohydrate restricted diet, says UAB expert

According to a new comprehensive financial analysis reported in the Journal of the American Medical Association and The Washington Post diabetes leads a list of just 20 diseases and conditions that account for more than half of all spending on healthcare in the United States.

30 Dec 2016

Novel mathematical model could help provide causes of complex multifactorial diseases

Patients with complex diseases have a higher risk of developing another. Multi-morbidity represents a huge problem in everyday clinical practice, because it makes it more difficult to provide successful treatment.

27 Dec 2016

Four-year Johns Hopkins program provides efficient, less expensive care for patients in East Baltimore

When people with chronic health problems couldn't get around town to their doctors' appointments, a four-year Johns Hopkins program brought the appointments to them.

25 Dec 2016

Making muscles burn more fat and less glucose could cause diabetes, say researchers

Making muscles burn more fat and less glucose can increase exercise endurance, but could simultaneously cause diabetes, says a team of scientists from Baylor College of Medicine and other institutions.

22 Dec 2016

Biomarker for oxidative stress plays key role in development of NAFLD, study shows

Diet-related diseases like non-alcoholic fatty liver disease (NAFLD) are known to have a major inflammatory component.

21 Dec 2016

FDA expands approved use of G5 Mobile Continuous Glucose Monitoring System

The U.S. Food and Drug Administration today expanded the approved use of Dexcom's G5 Mobile Continuous Glucose Monitoring System to allow for replacement of fingerstick blood glucose (sugar) testing for diabetes treatment decisions in people 2 years of age and older with diabetes.

21 Dec 2016

Bionic pancreas system manages blood sugar levels in patients with type 1 diabetes living at home

The bionic pancreas system developed by Boston University investigators proved better than either conventional or sensor-augmented insulin pump therapy at managing blood sugar levels in patients with type 1 diabetes living at home, with no restrictions, over 11 days.

20 Dec 2016

High levels of enzyme can predict memory impairment and Type 2 diabetes

An enzyme found in the fluid around the brain and spine is giving researchers a snapshot of what happens inside the minds of Alzheimer's patients and how that relates to cognitive decline.

19 Dec 2016

Researchers use worms as model system to study how gut microbiome influences disease

The billions of microorganisms living within the human digestive tract appear to play a significant role in health and disease, notably metabolic syndrome, autoimmune disorders and diabetes - but how these organisms do so is not well understood.

17 Dec 2016

Turning off 'fat-specific protein 27' improves blood sugar levels, reduces body fat in animal model

In a study published in the Journal of Lipid Research, Saint Louis University scientist Angel Baldan, Ph.D., reports that turning off a protein found in liver and adipose tissue significantly improves blood sugar levels, as well as reduces body fat in an animal model.

16 Dec 2016

Western diet during pregnancy may increase obesity risk in offspring

Diet composition around the time of pregnancy may influence whether offspring become obese, according to a new study using animal models at The Scripps Research Institute (TSRI).

15 Dec 2016

Research reveals opposing role for SNAP23 protein in endocrine and exocrine pancreas

Movement of secretory molecules, such as hormones and digestive enzymes, out of the cell is known as exocytosis. This process is guided by SNARE proteins, which help the fusion of secretory vesicles with the plasma membrane.

8 Dec 2016

Endocrine Society applauds Novo Nordisk for pledging to limit rising insulin prices

The Endocrine Society lauds Novo Nordisk's recent announcement that it would limit price increases for its therapies, including insulin, and hopes that other entities in the insulin supply chain including manufacturers, pharmacy benefit managers, and insurers will also demonstrate similar restraint to address this important issue.

From Novo Nordisk 8 Dec 2016

Survey: Only 1 in 3 patients discusses symptoms of hyperglycaemia with nurse or doctor

Only 1 in 3 discussed symptoms of high blood glucose levels (hyperglycaemia) with their nurse or doctor, according to a new survey of 200 people living with type 1 or type 2 diabetes, who need mealtime insulin to control their blood glucose levels.

8 Dec 2016

Investigational diabetes drug that impedes Parkinson's progression getting ready for human trials

A new investigational drug originally developed for type 2 diabetes is being readied for human clinical trials in search of the world's first treatment to impede the progression of Parkinson's disease following publication of research findings today in the journal Science Translational Medicine.

7 Dec 2016

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