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Vaccine generates antibodies that target SARS-CoV-2 spike protein regions shared among many coronaviruses

Could the SARS-CoV-2 vaccine reawaken previous antibody responses and point the way to a universal coronavirus vaccine? A new analysis of the antibody response to a COVID-19 vaccine suggests the immune system's history with other coronaviruses, including those behind the common cold, shapes the patient's response, according to a study published today in Cell Reports.

6 Jul 2022

Individuals under 65 years may be the predominant drivers of COVID-19 in West Africa

Researchers evaluated the effects of age structure and vaccine prioritization regarding COVID-19 in West Africa.

6 Jul 2022

COVID-19 vaccination with bacterial peptide conjugated to receptor-binding domain elicits potent immune response

In a new study, researchers assessed the efficiency of immunization with a bacterial peptide conjugated to the SARS-CoV-2 receptor-binding domain against SARS-CoV-2 infection.

6 Jul 2022

Vaccination against smallpox efficiently protects against monkeypox infection

In a new study, researchers assessed the existing information regarding monkeypox infections.

6 Jul 2022

Scientists explore mutations in the SARS-CoV-2 receptor-binding domain

Researchers assessed the different mutations of concern in the SARS-CoV-2 receptor-binding domain.

6 Jul 2022

Omicron infections have similar incubation periods but shorter generation intervals than Delta infections

Researchers assessed the differences between the generation-interval distributions and incubation periods of the SARS-CoV-2 Delta and Omicron variants.

6 Jul 2022

Targeting C5a/C5aR1 signaling ameliorates COVID-19 immunopathology

A new study investigated the role of complement component 5a (C5a) and its receptor (C5a receptor type 1, C5aR1) in the pathophysiology of COVID-19.

6 Jul 2022

Researchers reveal the exceptional capacity of Omicron to evade the immune system

The current wave of COVID-19 highlights a particularly high risk of reinfection by the Omicron variant of SARS-CoV-2.

6 Jul 2022

The host cell membrane binding surfaces of SARS-CoV-2 spike variants

Researchers identified SARS-CoV-2 spike surfaces involved in binding to host cell membranes.

6 Jul 2022

Beyond COVID-19: the potential future applications of mRNA vaccines

Researchers described the production, mechanisms, and potential applications of mRNA vaccines.

6 Jul 2022

Evaluation of antinucleocapsid antibody seropositivity following SARS-CoV-2 infection in vaccinated individuals

A new study assessed both placebo and vaccine recipients in the mRNA-1273 (Moderna) phase 3 clinical trial who were infected with SARS-CoV-2 during the blinded, placebo-controlled trial phase.

6 Jul 2022

Intrahost genetic diversity and evolution of the SARS-CoV-2 B.1.517 lineage during chronic infection of an immunocompromised individual

Researchers investigated the intrahost evolution and genetic diversity of the SARS-CoV-2 B.1.517 variant in an immunosuppressed person with chronic COVID-19.

6 Jul 2022

The global biogeography of bat-origin betacoronaviruses

Researchers developed a spatial and quantitative framework to explore the biogeography of and map the evolutionary risk of bat-origin βCoVs such as SARS-CoV, SARS-CoV-2 and MERS-CoV based on the geographic mosaic theory of coevolution.

6 Jul 2022

New atomic-level models of spike protein play a key role in COVID-19 infection and immunity

When the coronavirus causing COVID-19 infects human cells, the cell's protein-processing machinery makes modifications to the spike protein that render it more flexible and mobile, which could increase its ability to infect other cells and to evade antibodies, a new study from the University of Illinois Urbana-Champaign found.

6 Jul 2022

Research highlights importance of designing effective COVID vaccine allocation strategies

In a recent study posted to the medRxiv* pre-print server, researchers at the University of Melbourne used a modified Susceptible, Exposed, Infectious, and Recovered (SEIR) mathematical model to examine the impact of different vaccine mechanisms and disease characteristics on a population comprised of individuals at high and low risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

6 Jul 2022

Healthy, cancer, and immunosuppressed patients all benefit from COVID boosters

In a recent study posted to the medRxiv* pre-print server, researchers developed a mechanistic mathematical model to predict the course of vaccine-induced immunity in healthy and immunosuppressed patients for the long term, exceeding the time frames for which clinical data is currently available.

5 Jul 2022

Novel inhalable COVID-19 vaccine

A recent study published in the Nature Biomedical Engineering journal illustrated a novel inhalable SARS-CoV-2 vaccine candidate centered on exosomes (Exos) coupled with recombinant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor-binding domain (RBD).

5 Jul 2022

Scientists uncover HIV’s sweet spot

HIV researchers have long been trying to identify the specific cells that the virus prefers to infect and hide in. They know that HIV favors a special type of immune cells called memory CD4 T cells.

5 Jul 2022

Latest omicron subvariants are better at eluding vaccines and antibody treatments

The latest omicron subvariants-; including the BA.4 and BA.5 forms causing new surges in infections in the United States-; are even better at eluding vaccines and most antibody treatments than previous variants, finds a study by researchers at Columbia University Vagelos College of Physicians and Surgeons.

5 Jul 2022

Has the COVID pandemic affected breastfeeding intention?

A new study discusses the impact of the pandemic on breastfeeding practices.

5 Jul 2022

SARS News and Research

Vaccine generates antibodies that target SARS-CoV-2 spike protein regions shared among many coronaviruses

Individuals under 65 years may be the predominant drivers of COVID-19 in West Africa

COVID-19 vaccination with bacterial peptide conjugated to receptor-binding domain elicits potent immune response

Vaccination against smallpox efficiently protects against monkeypox infection

Scientists explore mutations in the SARS-CoV-2 receptor-binding domain

Omicron infections have similar incubation periods but shorter generation intervals than Delta infections

Targeting C5a/C5aR1 signaling ameliorates COVID-19 immunopathology

Researchers reveal the exceptional capacity of Omicron to evade the immune system

The host cell membrane binding surfaces of SARS-CoV-2 spike variants

Beyond COVID-19: the potential future applications of mRNA vaccines

Evaluation of antinucleocapsid antibody seropositivity following SARS-CoV-2 infection in vaccinated individuals

Intrahost genetic diversity and evolution of the SARS-CoV-2 B.1.517 lineage during chronic infection of an immunocompromised individual

The global biogeography of bat-origin betacoronaviruses

New atomic-level models of spike protein play a key role in COVID-19 infection and immunity

Research highlights importance of designing effective COVID vaccine allocation strategies

Healthy, cancer, and immunosuppressed patients all benefit from COVID boosters

Novel inhalable COVID-19 vaccine

Scientists uncover HIV’s sweet spot

Latest omicron subvariants are better at eluding vaccines and antibody treatments

Has the COVID pandemic affected breastfeeding intention?

Pioneering Live Cell Imaging - Yokogawa's Impact and Innovations

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

From Discovery Biology to ELRIG Chair

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