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Interferon beta-1a shows promise against MS

People who received injections of the multiple sclerosis (MS) drug interferon beta-1a soon after their first signs of possible MS were less likely to progress to clinically definite MS than people who switched to interferon beta-1a from placebo, according to new phase three results of the three-year REFLEXION clinical trial that will be presented as part of the Emerging Science program at the American Academy of Neurology's 64th Annual Meeting in New Orleans, April 21 to April 28, 2012.

20 Apr 2012

Positive data from Synairgen’s SNG001 Phase II trial on asthma

Scientists from the University of Southampton and Synairgen, a respiratory drug development company spun out from the University, can announce positive data from its Phase II clinical trial, into the effectiveness of the drug SNG001 (inhaled interferon beta) for asthma patients.

20 Apr 2012

White House science adviser responds to inquiry regarding handling of H5N1 research controversy

"White House science adviser John Holdren has replied to questions asked last month by Representative Jim Sensenbrenner (R-Wisc.) about how the Obama Administration has handled the controversy surrounding two studies that showed how to make the H5N1 avian influenza virus transmissible between mammals," ScienceInsider reports.

19 Apr 2012

1 in 5 Australians expect antibiotics for coughs and colds: New NPS campaign

The survey also revealed a plethora of misconceptions when it comes to antibiotics with only half of respondents knowing that bacteria are becoming resistant to antibiotics. Only 40% knew antibiotics should not be taken for viruses and many (40%) did not know that taking antibiotics when they’re not needed contributes to antibiotic resistance. More than half did not know resistance increases when you don’t complete the course as directed and in general, the youth audience had less knowledge.

18 Apr 2012

Flu outbreak at veterans home

State Veterans' Affairs Commissioner Linda Schwartz told The Associated Press that the veterans were taken to Hartford Hospital after a number began complaining of flu-like symptoms. The 18 men live at the Connecticut State Veterans Home in either the Sgt. John L. Levitow Veteran's Health Center or a residential facility.

17 Apr 2012

FDA grants 510(k) clearance for QIAGEN’s molecular detection PCR technology

QIAGEN N.V. today announced that the U.S. Food and Drug Administration (FDA) has granted two 510(k) clearances for its real-time PCR (polymerase chain reaction) instrument Rotor-Gene Q MDx and a compatible test for the detection of Influenza A/B, the artus Infl A/B RG RT-PCR Kit, for in vitro diagnostic use.

From QIAGEN Manchester Limited 17 Apr 2012

Flu shots offered to populations at risk at the beginning of season

All Care Inala Medical Centre doctor Michael Ho said flu shots were becoming more popular each year. “Flu seasons tends to begin in late March early April to June,” he said. “More and more people are opting to get vaccinations because they are promoted well within the community.” He added, “It is particularly important for elderly people to be immunized because their immune system is already not at its best…This is also the case for people who have chronic medical conditions like diabetes, severe asthma, or heart disease. With their current condition, if they catch the flu they can end up with a worse outcome.”

12 Apr 2012

Financial Times analysis examines efforts to address dual risk research

A Financial Times analysis examines how the international community is working "to ensure scientific work can proceed without falling prey to accidental leaks or malevolent intent," following controversy surrounding two studies on the H5N1 bird flu virus.

12 Apr 2012

Influenza vaccine recommended but select the appropriate vaccine

Further to advice issued by the RACGP and the Chief Medical Officer, NPS is encouraging health professionals to offer their patients influenza vaccination, especially for those at risk, but to be aware that the choice of influenza vaccine is important, especially for children.

11 Apr 2012

2-day meeting examining issues of censorship of scientific studies leaves questions unanswered

A two-day Royal Society meeting held this week in London -- which examined "whether scientific journals should occasionally publish censored versions of papers because the full ones might prove useful to terrorists" -- "brought scientists no closer to resolving the question of whether there are any kinds of experiments whose results should be kept from the public," the Washington Post reports.

6 Apr 2012

MedImmune's quadrivalent flu vaccine may protect children

An intranasal vaccine that includes four weakened strains of influenza could do a better job in protecting children from the flu than current vaccines, Saint Louis University research shows.

4 Apr 2012

Discussion of NSABB recommendation to publish controversial bird flu studies to continue in London meeting

The National Science Advisory Board for Biosecurity's (NSABB) "reversal on publishing two controversial H5N1 studies is poised to shift discussions on the topic that continue in London this week, as more participants in the debate weigh in following the March 30 announcement," CIDRAP News reports.

4 Apr 2012

NSABB recommends full publication of controversial bird flu studies

The National Science Advisory Board for Biosecurity (NSABB) on Friday recommended that revised versions of two controversial studies on H5N1 avian flu be published in scientific journals, reversing its previous recommendation that the studies only be published if certain details were withheld, the New York Times reports.

3 Apr 2012

Controversial study on lethal bird flu virus strain to be published

The controversial study on lethal flu virus strain is likely to be published in full. Last December the National Science Advisory Board for Biosecurity - NSABB recommended the two papers not be published in full by the journals - Nature and Science. The panel was concerned that details of the studies, which induced mutations in the H5N1 avian flu virus that made it transmissible among mammals by air rather than by close physical contact, could be used for bioterrorism. Critics of the recommendation raised fears that important science was being censored.

2 Apr 2012

Study sheds light on cellular mechanisms involved in flu resistance

Scientists from the University of Utah School of Medicine have discovered that a mouse protein called IFITM3 contributes to the body's defense against some types of viral infections by binding to an enzyme responsible for regulating the pH of a cell's waste disposal system.

2 Apr 2012

U.S. releases policy requiring dual-use biological research reviews amid bird flu debate

"The U.S. government on Thursday released a new policy that will require federal agencies to systematically review the potential risks associated with federally funded studies involving 15 'high consequence' pathogens and toxins, including the H5N1 avian influenza virus," Science Insider reports.

31 Mar 2012

Abbott receives CE Marking for PLEX-ID instrument and assays

Abbott announced today it has obtained CE Marking (Conformite Europeene) in the European Union to market its rapid, high-throughput PLEX-ID instrument, along with three assays for use on the system: PLEX-ID Viral IC Spectrum, PLEX-ID BAC Spectrum BC and PLEX-ID Flu.

31 Mar 2012

Researchers, experts debate publication of H5N1 research amid updated studies

"As researchers from both sides of the debate over two controversial H5N1 studies weighed in Tuesday on full publication versus a more cautionary approach, two U.S. journals" -- the Journal of Infectious Diseases (JID) and its sister publication, Clinical Infectious Diseases -- "said they are developing policies to address any future such instances," CIDRAP News writes.

30 Mar 2012

Scientific research is crucial to preventing, controlling, eradicating infectious diseases

The debate about two studies showing that, with few genetic mutations, H5N1 bird flu strains could become more easily transmissible among ferrets, a laboratory model for humans, "has become a debate about the role of science in society.