Immune System News and Research

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Researchers decipher when and why T cells become non-responsive to immunotherapy

Non-small cell lung cancer is the most common type of lung cancer in humans. Some patients with NSCLC receive a therapy called immune checkpoint blockade (ICB) that helps kill cancer cells by reinvigorating a subset of immune cells called T cells, which are "exhausted" and have stopped working.

30 Oct 2021

Scientists develop new approach to combat treatment-resistant melanoma

Researchers from the Centenary Institute have developed a new approach to fighting melanomas that fail to respond – or are resistant – to standard treatments. The deadliest form of skin cancer, melanoma is responsible for more than 1,700 deaths each year in Australia.

30 Oct 2021

New project investigates stem cell therapy as a potential treatment for glaucoma

Oregon Health & Science University is part of a national research project investigating stem cell therapy as a potential treatment for glaucoma, the world's second leading cause of blindness.

29 Oct 2021

Study discovers inflammatory mediator critically involved in bacterial pneumonia

Researchers at Karolinska Institutet in Sweden report that a recently discovered inflammatory mediator, interleukin-26, appears to have an important role in pneumonia and contribute to the killing of bacteria.

29 Oct 2021

UKHSA’s Green Book updated to allow flexibility in COVID-19 booster vaccines for vulnerable people

COVID-19 booster vaccines can now be given sooner than six months after their second dose to certain vulnerable people where this makes operational sense, as the UKHSA's Green Book has been updated.

29 Oct 2021

Study uncovers unknown effects of COVID-19 virus on the immune system

COVID-19 reduces the numbers and functional competence of certain types of immune cells in the blood, say LMU researchers. This could affect responses to secondary infections.

28 Oct 2021

UAB researchers show how to identify non-responding tumors and improve immunotherapy response

Immunotherapy using checkpoint inhibitors can work well to treat cancer, but only a minority of patients respond to therapy.

28 Oct 2021

Third dose of Covid-19 vaccine benefits dialysis patients

In some patients, the immune system responds poorly to the second vaccination dose. This changes with the third shot.

28 Oct 2021

Immune cell patterns can help predict if kidney cancer patients will respond to immunotherapy

Researchers at the Francis Crick Institute, The Royal Marsden NHS Foundation Trust and UCL have found immune cell patterns within tumors that can help predict if patients with kidney cancer will respond to immunotherapy.

28 Oct 2021

Study finds one mRNA vaccine dose after SARS-CoV-2 infection produces highest neutralizing antibody titers

Researchers investigated the neutralizing antibody response that different mRNA vaccines induce in both previously convalescent and SARS-CoV-2 naïve individuals.

28 Oct 2021

New mechanisms for treating impregnable KRAS mutant cancers with statins

Third-generation cancer immunotherapy, a method of removing cancer using the body's immune system, has shown remarkable clinical benefits in recent years, giving hopes to many researchers and patients.

27 Oct 2021

Taking lessons in molecular therapeutics from earthworms to combat COVID

Scientists were interested in further investigating the defense mechanism of earthworms in an effort to discover therapeutic solutions against SARS-CoV-2.

27 Oct 2021

Research reveals the microbial landscape of patients with systemic lupus erythematosus

Systemic lupus erythematosis (SLE) is an autoimmune disease in which the immune system targets tissues of the body, causing widespread inflammation and affecting multiple organs such as the kidney and the brain.

27 Oct 2021

Studies test intravenous immunoglobulin for treatment of Kawasaki disease and MIS-C

Kawasaki disease (KD) is rare, with fewer than 6,000 diagnosed cases per year in the United States. It is most common in infants and young children and causes inflammation in the walls of some blood vessels in the body.

27 Oct 2021

New study explains why Delta is so easily transmitted and infects people quickly

The Delta variant of SARS-CoV-2 has swept the globe, becoming the dominant variant within just a few months. A new study from Boston Children's Hospital, published today in Science, explains why Delta is so easily spread and infects people so quickly, and suggests a more targeted strategy for developing future COVID-19 vaccines and treatments.

27 Oct 2021

UQ researchers find that SARS-CoV-2 virus does not infect blood vessels

The SARS-CoV-2 virus does not infect blood vessels, despite the high risk of blood clots to COVID-19 patients, University of Queensland researchers have found.

26 Oct 2021

Study identifies how cancer cells transform macrophages into supporters of their growth

A Ludwig Cancer Research study has identified a means by which cancer cells engineer the conversion of immune cells known as macrophages from destroyers of tumors to supporters of their growth and survival.

26 Oct 2021

Frequency domain optical imaging could reliably identify lupus arthritis and track disease progression

Systemic lupus erythematosus (SLE), commonly referred to as simply "lupus", is an autoimmune disorder where the body's immune system attacks healthy tissue.

26 Oct 2021

Fermented soy product suppresses airway inflammation in animal models of asthma

Bronchial asthma causes symptoms such as wheezing and cough due to chronic airway inflammation, but there is no fundamental treatment for it, leaving a desire for new prevention and treatment methods.

26 Oct 2021

Immune response to mRNA COVID vaccines delayed in pregnant women

Researchers in the United States have conducted comprehensive profiling of humoral immune responses in pregnant, lactating, and non-pregnant women following coronavirus disease 2019 (COVID-19) messenger RNA (mRNA) vaccination to probe differences in vaccine-induced immunity.

25 Oct 2021

Immune System News and Research

Researchers decipher when and why T cells become non-responsive to immunotherapy

Scientists develop new approach to combat treatment-resistant melanoma

New project investigates stem cell therapy as a potential treatment for glaucoma

Study discovers inflammatory mediator critically involved in bacterial pneumonia

UKHSA’s Green Book updated to allow flexibility in COVID-19 booster vaccines for vulnerable people

Study uncovers unknown effects of COVID-19 virus on the immune system

UAB researchers show how to identify non-responding tumors and improve immunotherapy response

Third dose of Covid-19 vaccine benefits dialysis patients

Immune cell patterns can help predict if kidney cancer patients will respond to immunotherapy

Study finds one mRNA vaccine dose after SARS-CoV-2 infection produces highest neutralizing antibody titers

New mechanisms for treating impregnable KRAS mutant cancers with statins

Taking lessons in molecular therapeutics from earthworms to combat COVID

Research reveals the microbial landscape of patients with systemic lupus erythematosus

Studies test intravenous immunoglobulin for treatment of Kawasaki disease and MIS-C

New study explains why Delta is so easily transmitted and infects people quickly

UQ researchers find that SARS-CoV-2 virus does not infect blood vessels

Study identifies how cancer cells transform macrophages into supporters of their growth

Frequency domain optical imaging could reliably identify lupus arthritis and track disease progression

Fermented soy product suppresses airway inflammation in animal models of asthma

Immune response to mRNA COVID vaccines delayed in pregnant women

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