Genetic News and Research

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Microarray analysis improves prenatal diagnosis

A "chip" or array that can quickly detect disorders such as Down syndrome or other diseases associated with chromosomal abnormalities proved an effective tool in prenatal diagnosis in a series of 300 cases at Baylor College of Medicine, said researchers in a report that appears in the current issue of the journal Prenatal Diagnosis.

17 Nov 2008

Early detection program for men with a high prostate cancer risk

Men with a family history of prostate cancer and African-American men are particularly susceptible to the disease, with a twofold to sevenfold increased risk. Assessing risk in these populations has been difficult.

17 Nov 2008

Variations within three genes associated with lipid peroxidation could increase kidney cancer risk

A team of international scientists has identified three genes associated with the body's processing of fats that may increase susceptibility to kidney cancer.

17 Nov 2008

Four new colorectal cancer genes found

Canadian researchers collaborating in a large, international study played a key role in identifying four new genes for colorectal cancer.

17 Nov 2008

Expert concerned genetic research could awaken racist attitudes

People are different, both physically and mentally, but genetically everyone is very similar.

17 Nov 2008

Breast cancer common among women with family history but without BRCA1 or BRCA2 mutation

New data presented at the American Association for Cancer Research's Seventh Annual International Frontiers in Cancer Prevention Research meeting outlines new data, which assesses breast cancer risk among women with a strong family history of breast cancer, but without a BRCA1 or BRCA2 mutation.

17 Nov 2008

Protein enzyme BubR1 provides new understanding of processes behind cancer-cell survival and drug-resistance

A study of how one protein enzyme, BubR1, helps make sure chromosomes are equally distributed during mitosis might explain how the process of cell division goes so awry in cancer, according to researchers from Fox Chase Cancer Center.

17 Nov 2008

Scientists discover how certain antibiotics kill bacteria

A series of genetic clues led a team of Boston University biomedical engineers to uncover exactly how certain antibiotics kill bacteria.

17 Nov 2008

'Intelligent' cancer drug development boosts success rates

A new era of intelligent cancer drug development has spurred a leap in the proportion of drugs reaching patients, according to a study by Cancer Research UK scientists published in Nature Reviews Drug Discovery.

17 Nov 2008

World's earliest nuclear family found

The earliest evidence of a nuclear family, dating back to the Stone Age, has been uncovered by an international team of researchers, including experts from the University of Bristol.

17 Nov 2008

Blood exosomes shown to contain tumor-specific genetic information for brain cancer

Tiny vesicles called exosomes released into the bloodstream from aggressive brain tumors contain genetic signatures that may help guide future diagnosis and treatment of this deadly disease.

17 Nov 2008

University of Illinois at Chicago joins international research effort on autism

Researchers at the University of Illinois at Chicago are taking part in an international effort to gather DNA samples from 2,000 autism patients and their families over the next three years.

16 Nov 2008

Scientists find intra cellular pathway driving a deadly sub-type of breast cancer

An intra cellular pathway not previously linked to breast cancer is driving a sub-type of the disease that is highly lethal and disproportionately over-represented in African American women.

16 Nov 2008

Early-onset familial Alzheimer disease provides clues to treatment of common Alzheimer's

The rarest kind of Alzheimer Disease (AD) - the form that transmits from parent to child with a cruel 50 percent likelihood - has been valued for its potential to shed light for the millions of people affected by the common form of AD.

16 Nov 2008

Microvesicles released from glioblastoma cells carry information that may guide treatment

Microvesicles - tiny membrane-covered sacs - released from glioblastoma cells contain molecules that may provide data that can guide treatment of the deadly brain tumor.

16 Nov 2008

Seniors with sharp brains reveal first secrets of sharp memory in old age

Maybe you have an 85-year-old grandfather who still whips through the newspaper crossword puzzle every morning or a 94-year-old aunt who never forgets a name or a face.

16 Nov 2008

Previously unknown regulatory step during HIV replication provides potential new target for HIV/AIDS therapy

A previously unknown regulatory step during human immunodeficiency (HIV) replication provides a potentially valuable new target for HIV/AIDS therapy, report researchers at the Salk Institute for Biological Studies and the University of Wisconsin, Madison.

16 Nov 2008

Discovery of key contributor to Alzheimer's disease process

Walter J. Lukiw, PhD, Associate Professor of Neuroscience and Ophthalmology at LSU Health Sciences Center New Orleans, is the lead author of a paper identifying, for the first time, a specific function of a fragment of ribonucleic acid (RNA), once thought to be no more than a byproduct, in regulating inflammation and the development of Alzheimer's disease.

16 Nov 2008

Potential new therapeutic targets for rejuvenating the aged immune system

In the November 15th issue of G&D, Dr. Kenneth Dorshkind and colleagues at the David Geffen School of Medicine (UCLA) have identified two genes - p16(Ink4a) and Arf - that sensitize lymphoid progenitor cells to the effects of aging, and confer resistance to leukemogenesis.

16 Nov 2008

Breakthrough in cellular analysis

Like skilled assassins, many diseases seem to know exactly what types of cells to attack.

16 Nov 2008

Genetic News and Research

Microarray analysis improves prenatal diagnosis

Early detection program for men with a high prostate cancer risk

Variations within three genes associated with lipid peroxidation could increase kidney cancer risk

Four new colorectal cancer genes found

Expert concerned genetic research could awaken racist attitudes

Breast cancer common among women with family history but without BRCA1 or BRCA2 mutation

Protein enzyme BubR1 provides new understanding of processes behind cancer-cell survival and drug-resistance

Scientists discover how certain antibiotics kill bacteria

'Intelligent' cancer drug development boosts success rates

World's earliest nuclear family found

Blood exosomes shown to contain tumor-specific genetic information for brain cancer

University of Illinois at Chicago joins international research effort on autism

Scientists find intra cellular pathway driving a deadly sub-type of breast cancer

Early-onset familial Alzheimer disease provides clues to treatment of common Alzheimer's

Microvesicles released from glioblastoma cells carry information that may guide treatment

Seniors with sharp brains reveal first secrets of sharp memory in old age

Previously unknown regulatory step during HIV replication provides potential new target for HIV/AIDS therapy

Discovery of key contributor to Alzheimer's disease process

Potential new therapeutic targets for rejuvenating the aged immune system

Breakthrough in cellular analysis

eBook: Using iPSCs models for human disease research and drug discovery eBook

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