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New results help predict treatment response in colorectal cancer

Genetic testing can identify a group of patients with advanced colorectal cancer who are likely to survive on average twice as long if treated with the drug cetuximab, late breaking results show.

16 Sep 2008

Migraine sufferers more at risk of deadly blood clots

According to new research migraine sufferers may be more at risk of developing deadly blood clots in their veins.

16 Sep 2008

Variations in cyclin D1 gene increase susceptibility to malignant melanoma

People who carry a particular genetic variant are at significantly increased risk of developing malignant melanoma, new research shows.

15 Sep 2008

Scientists identify kidney failure susceptibility gene

Scientists at Johns Hopkins schools of Public Health and Medicine have, for the first time, identified variants in the gene MYH9 that are associated with increased risk for non-diabetic end stage renal disease (ESRD,) which is the near-loss of kidney function leading to either dialysis of transplant. MYH9, located on the 22 chromosome, is the first gene identified for common forms of kidney disease.

15 Sep 2008

Inovio Biomedical achieves 75% complete response rate in preclinical testing of DNA-based cancer vaccine using its electroporation DNA delivery system

Inovio Biomedical Corporation announced today that it achieved positive results from its proprietary research and development program for DNA-based cancer vaccines delivered using the company's electroporation-based DNA delivery technology.

15 Sep 2008

Significant benefits in non-small-cell lung cancer from customizing erlotinib treatment

Lung cancer patients whose tumors carry specific genetic mutations can achieve significantly longer survival when treated with targeted therapies such as erlotinib, Spanish researchers report.

15 Sep 2008

Study shows high gum disease rates in rural Appalachia

Research on 445 families centered in two Pennsylvania towns and two West Virginia counties shows that 80 percent of adults suffer from more severe forms of periodontal disease, according to Richard Crout, D.M.D., Ph.D., an expert on gum disease and associate dean for research in the West Virginia University School of Dentistry.

14 Sep 2008

Scientists discover common variants in the human genome conferring risk of bladder cancer

Scientists at deCODE genetics and colleagues at Radboud University Medical Center in the Netherlands today report the discovery of two common single-letter variants in the human genome (SNPs) that confer increased risk of urinary bladder cancer.

14 Sep 2008

BioServe introduces customizable DNA panels for genetic research

BioServe has announced a more affordable pricing plan for its vast bank of DNA with comprehensive, de-identified, covariate data that includes age, gender, diet, body mass index (BMI), and race. In addition, each sample has data on the complete diagnostic and treatment history of the donor.

14 Sep 2008

Phase I trial for new tuberculosis vaccine

This week, a new vaccine "VPM1002" has entered the clinical phase I trial in Neuss, Germany, where it is being tested for safety on voluntary subjects. VPM1002 is based on a vaccine that has been in use since 1921, and has been genetically engineered to prevent infection with tuberculosis bacteria much more effectively than its predecessor.

11 Sep 2008

Risk of breast cancer mutations underestimated for Asian women, Stanford study shows

Oncologist Allison Kurian, MD, and her colleagues at the Stanford University School of Medicine were perplexed. Computer models designed to identify women who might have dangerous genetic mutations that increase their risk of breast and ovarian cancer worked well for white women. But they seemed to be less reliable for another ethnic group.

11 Sep 2008

Genetic mutation prevents fetal malaria transmission, study says

A genetic mutation of the fetal gene sFlt1 might protect fetuses of first-time pregnant women from contracting malaria, according to a study published online Sept. 8 in Proceedings of the National Academy of Sciences, ANI/Thaindian News reports.

11 Sep 2008

Democratic Vice Presidential Nominee Biden discusses health care proposal of GOP Presidential Nominee McCain

Democratic vice presidential nominee Sen. Joseph Biden (Del.) on Tuesday during a campaign event in Mehlville, Mo., said that Republican presidential nominee Sen. John McCain (Ariz.) as president would place employer-sponsored health insurance at risk, the St. Louis Post-Dispatch reports.

11 Sep 2008

Protein opens hope of treatment for cystic fibrosis patients

Scientists have finally identified a direct role for the missing protein that leaves cystic fibrosis patients open to attack from lung-damaging bacteria, the main reason most of them die before their 35th birthday, scientists heard today (Thursday 11 September 2008) at the Society for General Microbiology's Autumn meeting being held this week at Trinity College, Dublin.

10 Sep 2008

Herpes virus changes anti-herpes drug acyclovir to form that hinders AIDS virus

The drug acyclovir has long been used to suppress outbreaks of oral and genital herpes. Herpes viruses change acyclovir to a form that prevents them from reproducing.

10 Sep 2008

Personal DNA scanning service 23andMe drops price to $399

Personal DNA scanning service 23andMe on Tuesday is scheduled to announce that it is lowering the price of its gene-mapping service from $999 to $399 in order to attract more customers and expand its database of individual genetic profiles to bolster medical research, the San Francisco Chronicle reports.

10 Sep 2008

New drug hope for cystic fibrosis patients

A science conference in the UK has heard some good news which offers hope to cystic fibrosis (CF) patients worldwide.

10 Sep 2008

New drug hope for cystic fibrosis patients

A new drug therapy may represent a tremendous step forward in the treatment of some 70,000 cystic fibrosis (CF) patients worldwide, Dr David Sheppard from the University of Bristol told an audience at the BA Festival of Science in Liverpool today [9 September].

9 Sep 2008

Study identifies proteins that help provide immunity against HIV among commercial sex workers in Kenya

In a study published Wednesday in the Journal of Proteome Research, researchers from the University of Manitoba, along with participants from Canada's National Microbiology Laboratory and the University of Nairobi, indentified more than 15 proteins in a group of Kenyan commercial sex workers thought to have a natural immunity to HIV, the Winnipeg Free Press reports (Tremain, Winnipeg Free Press, 9/4).

9 Sep 2008

Physical activity can blunt the effect of obesity genes

People who are concerned that they may have a genetic susceptibility for obesity will find some relief from new research conducted in the U.S.

9 Sep 2008

Genetic News and Research

New results help predict treatment response in colorectal cancer

Migraine sufferers more at risk of deadly blood clots

Variations in cyclin D1 gene increase susceptibility to malignant melanoma

Scientists identify kidney failure susceptibility gene

Inovio Biomedical achieves 75% complete response rate in preclinical testing of DNA-based cancer vaccine using its electroporation DNA delivery system

Significant benefits in non-small-cell lung cancer from customizing erlotinib treatment

Study shows high gum disease rates in rural Appalachia

Scientists discover common variants in the human genome conferring risk of bladder cancer

BioServe introduces customizable DNA panels for genetic research

Phase I trial for new tuberculosis vaccine

Risk of breast cancer mutations underestimated for Asian women, Stanford study shows

Genetic mutation prevents fetal malaria transmission, study says

Democratic Vice Presidential Nominee Biden discusses health care proposal of GOP Presidential Nominee McCain

Protein opens hope of treatment for cystic fibrosis patients

Herpes virus changes anti-herpes drug acyclovir to form that hinders AIDS virus

Personal DNA scanning service 23andMe drops price to $399

New drug hope for cystic fibrosis patients

New drug hope for cystic fibrosis patients

Study identifies proteins that help provide immunity against HIV among commercial sex workers in Kenya

Physical activity can blunt the effect of obesity genes

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