Radiation Therapy News and Research

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Radiation therapy (also called radiotherapy, x-ray therapy, or irradiation) is the use of a certain type of energy (called ionizing radiation) to kill cancer cells and shrink tumors. Radiation therapy injures or destroys cells in the area being treated (the “target tissue”) by damaging their genetic material, making it impossible for these cells to continue to grow and divide. Although radiation damages both cancer cells and normal cells, most normal cells can recover from the effects of radiation and function properly. The goal of radiation therapy is to damage as many cancer cells as possible, while limiting harm to nearby healthy tissue.

FISH technique can be used to probe sperm DNA for chromosomal defects

Chemotherapy and radiation treatments are known to cause harsh side effects that patients can see or feel throughout their bodies.

19 Jan 2021

Researchers discover a new approach to inhibit intrahepatic cholangiocarcinoma

Reprogramming the rich connective tissue microenvironment of a liver cancer known as intrahepatic cholangiocarcinoma (ICC) inhibits its progression and resistance to standard chemotherapy in animal models, researchers from Massachusetts General Hospital have found.

12 Jan 2021

Gut microbe may play a role in the development of breast cancers

A microbe found in the colon and commonly associated with the development of colitis and colon cancer also may play a role in the development of some breast cancers, according to new research from investigators with the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

6 Jan 2021

Researchers apply AI to help physicians customize treatments for patients with oral cancers

Researchers at Case Western Reserve University and partners in the United States and India are applying the investigative and predictive capabilities of artificial intelligence (AI) to help physicians customize treatments for patients with oral squamous cell carcinomas.

5 Jan 2021

Study uncovers why cancer patients with liver metastases have poor outcomes

Michael Green, M.D., Ph.D., noticed that when his patients had cancer that spread to the liver, they fared poorly – more so than when cancer spread to other parts of the body. Not only that, but transformative immunotherapy treatments had little impact for these patients.

4 Jan 2021

Biologist receives NIH grant to build software tools to predict cancer drug efficacy

One of the most promising areas of human cancer research is the study of signal transduction, or cell signaling.

4 Jan 2021

Surgery may increase length of survival for metastatic breast cancer patients

Surgery, in addition to treatments like chemotherapy and radiation therapy, may increase the length of survival for metastatic breast cancer patients, according to Penn State College of Medicine and Penn State Cancer Institute researchers.

28 Dec 2020

Surgery associated with better survival in metastatic breast cancer patients

22 Dec 2020

No added risks to radiation therapy for cancer patients with COVID-19, says study

A team of radiation oncologists at the Zucker School of Medicine at Hofstra/Northwell in the United States aimed to determine if COVID-19 infected cancer patients receiving radiation therapy (RT) have any different outcome than non-infected patients.

17 Dec 2020

Genomic and immune indicators can help identify prostate cancer patients at high risk of lethal outcomes

Prostate cancer is one of the most common cancers among men in the United States. One in nine men will be diagnosed during his lifetime.

15 Dec 2020

Single-dose radiation therapy may lessen, eliminate unsafe additional outside trips during the pandemic

According to recent studies, an increase in the COVID-19 positivity rate correlates to an increase in mortality from non-coronavirus-related diseases.

14 Dec 2020

Physicians don't always recognize radiation therapy side effects in cancer patients

Physicians did not recognize side effects from radiation therapy in more than half of breast cancer patients who reported a significant symptom, a new study finds.

9 Dec 2020

Omitting postoperative radiation therapy did not compromise survival for older HR-positive breast cancer patients

Older patients with hormone receptor-positive breast cancer who did not receive radiation therapy after breast-conserving surgery had higher rates of local recurrence but similar 10-year survival rates when compared to patients who received postoperative radiation therapy, according to updated 10-year data from the PRIME II study, presented at the 2020 San Antonio Breast Cancer Symposium, held Dec. 8-11.

9 Dec 2020

Symptom under-recognition may be common in breast cancer patients treated with radiotherapy

Among patients with breast cancer treated with radiotherapy, under-recognition of symptoms was common in reports of pain, pruritus, edema, and fatigue, with younger patients and Black patients having significantly increased odds of symptom under-recognition, according to data presented at the 2020 San Antonio Breast Cancer Symposium, held Dec. 8-11.

9 Dec 2020

Repair protein may prevent damage to healthy cells during cancer therapy

A key way radiation therapy and chemotherapy work is by making highly lethal double-strand breaks in the DNA of cancer cells.

9 Dec 2020

Targeting senescent 'zombie' cells may improve survival in women with cervical cancer

How well women with cervical cancer respond to treatment and survive correlates with the level of 10 proteins in their blood that also are associated with a "zombie" cell state called senescence, Medical College of Georgia scientists report.

7 Dec 2020

First PSMA-targeted PET imaging drug approved for men with prostate cancer

Today, the U.S. Food and Drug Administration approved Gallium 68 PSMA-11 (Ga 68 PSMA-11) - the first drug for positron emission tomography (PET) imaging of prostate-specific membrane antigen (PSMA) positive lesions in men with prostate cancer.

1 Dec 2020

Machine learning model identifies which drug combinations kill tumor cells

When healthcare professionals treat patients suffering from advanced cancers, they usually need to use a combination of different therapies. In addition to cancer surgery, the patients are often treated with radiation therapy, medication, or both.

1 Dec 2020

Gut microbiota directly shapes the makeup of human immune system, shows study

MSK researchers have uncovered an important finding about the relationship between the microbiota and the immune system, showing for the first time that the concentration of different types of immune cells in the blood changes in relation to the presence of different bacterial strains in the gut.

1 Dec 2020

Cost of prostate cancer treatment can be a major source of stress for men, their families

For men with early-stage prostate cancer, choices about initial treatment carry varying risks of "financial toxicity," reports a study in The Journal of Urology®, Official Journal of the American Urological Association (AUA). The journal is published in the Lippincott portfolio by Wolters Kluwer.

1 Dec 2020

Radiation Therapy News and Research

Further Reading

FISH technique can be used to probe sperm DNA for chromosomal defects

Researchers discover a new approach to inhibit intrahepatic cholangiocarcinoma

Gut microbe may play a role in the development of breast cancers

Researchers apply AI to help physicians customize treatments for patients with oral cancers

Study uncovers why cancer patients with liver metastases have poor outcomes

Biologist receives NIH grant to build software tools to predict cancer drug efficacy

Surgery may increase length of survival for metastatic breast cancer patients

Surgery associated with better survival in metastatic breast cancer patients

No added risks to radiation therapy for cancer patients with COVID-19, says study

Genomic and immune indicators can help identify prostate cancer patients at high risk of lethal outcomes

Single-dose radiation therapy may lessen, eliminate unsafe additional outside trips during the pandemic

Physicians don't always recognize radiation therapy side effects in cancer patients

Omitting postoperative radiation therapy did not compromise survival for older HR-positive breast cancer patients

Symptom under-recognition may be common in breast cancer patients treated with radiotherapy

Repair protein may prevent damage to healthy cells during cancer therapy

Targeting senescent 'zombie' cells may improve survival in women with cervical cancer

First PSMA-targeted PET imaging drug approved for men with prostate cancer

Machine learning model identifies which drug combinations kill tumor cells

Gut microbiota directly shapes the makeup of human immune system, shows study

Cost of prostate cancer treatment can be a major source of stress for men, their families

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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