Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Study links low- and high-birthweight babies to increased cardiovascular disease risk

For reasons that remain unclear at least in the smaller babies, both birthweight extremes appear to increase the likelihood of early development of dangerous fat around major organs in the abdomen that significantly increases these risks, said Dr. Brian Stansfield, neonatologist at the Children's Hospital of Georgia and the Medical College of Georgia at Augusta University.

24 May 2016

Epigenetic modification of Igfbp2 gene may increase risk of obesity and fatty liver

Scientists of the German Center for Diabetes Research led by the German Institute of Human Nutrition have shown in a mouse model that the epigenetic modification of the Igfbp2 gene observed in the young animal precedes a fatty liver in the adult animal later in life.

24 May 2016

Four major phenotypes may help improve prediction, prevention of cardiometabolic risk in prediabetes

Prediabetes is associated with increased risk of diabetes, cardiovascular disease, dementia and cancer. However, the disease risk considerably varies among subjects.

21 May 2016

Cardioprotective effect proposed for metformin

A large retrospective analysis suggests that metformin could be cardioprotective in insulin-dependent patients with Type 2 diabetes.

21 May 2016

Researchers identify single RCAN1 gene responsible for onset of type 2 diabetes

RESEARCHERS have identified the gene they believe is responsible for the onset of type 2 diabetes, sparking hope for treatments to prevent and possibly reverse the progressive condition.

20 May 2016

PYY hormone may offer effective treatment for type 2 diabetes

Researchers at the Norwegian University of Science and Technology and Oxford University have found a hormone that may offer an effective treatment for type 2 diabetes.

20 May 2016

TAK1 deficit protects mice from obesity

Obesity and subsequent complications are increasing in frequency worldwide. The accumulation of adipose tissue is associated with increased inflammation, and it has been proposed that modification of proinflammatory responses could alter adipose tissue composition.

20 May 2016

Exposure to bright light may influence metabolism

Exposure to bright light could affect your metabolism, reports a new Northwestern Medicine study.

19 May 2016

CGT, University of Aberdeen announce creation of new company to develop novel technology for diabetes treatment

The Cell and Gene Therapy Catapult and University of Aberdeen, UK, today announce the creation of Islexa, a new company developing a novel technology to produce laboratory grown islets, the organoids responsible for insulin production.

18 May 2016

Insulin pump therapy can benefit all type 1 diabetes patients

Insulin pump therapy contributes to better blood glucose control in type 1 diabetes and, as pump technology continues to improve and become part of sensor-controlled feedback and artificial pancreas systems, essentially all patients would benefit from their capabilities according to a Commentary published in Diabetes Technology & Therapeutics (DTT), a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

18 May 2016

McGill researchers discover role of folliculin protein in regulating activity of fat cells

Researchers have uncovered a new molecular pathway for stimulating the body to burn fat - a discovery that could help fight obesity, diabetes and cardiovascular disease.

17 May 2016

Sleep hormone melatonin may be responsible for type 2 diabetes risk among overnight workers

A new experimental and clinical study from Lund University in Sweden shows that the sleep hormone melatonin impairs insulin secretion in people with a common gene variant.

13 May 2016

Chronic alcohol exposure could negatively impact pancreas' ability to absorb vitamin C

Chronic exposure to alcohol interferes with the pancreas' ability to absorb vitamin C, potentially predisposing the body to pancreatitis and other pancreatic diseases, a new study in the American Journal of Physiology—Cell Physiology reports.

12 May 2016

Combination of two compounds found in red grapes, oranges could treat diseases

A combination of two compounds found in red grapes and oranges could be used to improve the health of people with diabetes, and reduce cases of obesity and heart disease.

12 May 2016

Researchers produce insulin-secreting cells from stem cells of diabetic patients

Signaling a potential new approach to treating diabetes, researchers at Washington University School of Medicine in St. Louis and Harvard University have produced insulin-secreting cells from stem cells derived from patients with type 1 diabetes.

11 May 2016

Oral regimens could offer simple solution for severe hyperglycaemia

Study findings indicate that oral treatments could offer a simpler alternative to upfront insulin for patients who have severe hyperglycaemia at the time of diagnosis with Type 2 diabetes.

10 May 2016

Digital health: putting patients at the center. An interview with Roz Davies

In England alone the NHS sees 1 million patients every 36 hours and there are 3 million volunteers across health and social care many of whom are motivated by their personal experience of healthcare services.

10 May 2016

Videogame addiction may impact sleep habits, obesity and cardio-metabolic health among children and teens

Some children and youth with high videogame addiction tendencies may be at risk of sleep deprivation and disorders associated with obesity and poor cardio-metabolic health, Hamilton researchers have found.

10 May 2016

Study shows over-expression of adhesion molecules in fat tissues protects mice from obesity, diabetes

Okayama University researchers report that the overexpression of an adhesion molecule found on the surface of fat cells appears to protect mice from developing obesity and diabetes. The findings, published in the journal Diabetes, March 2016, may fuel the development of new therapies targeting these diseases.

9 May 2016

Cancerous lung tumors can alter metabolism by hijacking circadian mechanisms

University of California, Irvine scientists who study how circadian rhythms - our own body clocks - control liver function have discovered that cancerous lung tumors can hijack this process and profoundly alter metabolism.

6 May 2016

Insulin News and Research

Further Reading

Study links low- and high-birthweight babies to increased cardiovascular disease risk

Epigenetic modification of Igfbp2 gene may increase risk of obesity and fatty liver

Four major phenotypes may help improve prediction, prevention of cardiometabolic risk in prediabetes

Cardioprotective effect proposed for metformin

Researchers identify single RCAN1 gene responsible for onset of type 2 diabetes

PYY hormone may offer effective treatment for type 2 diabetes

TAK1 deficit protects mice from obesity

Exposure to bright light may influence metabolism

CGT, University of Aberdeen announce creation of new company to develop novel technology for diabetes treatment

Insulin pump therapy can benefit all type 1 diabetes patients

McGill researchers discover role of folliculin protein in regulating activity of fat cells

Sleep hormone melatonin may be responsible for type 2 diabetes risk among overnight workers

Chronic alcohol exposure could negatively impact pancreas' ability to absorb vitamin C

Combination of two compounds found in red grapes, oranges could treat diseases

Researchers produce insulin-secreting cells from stem cells of diabetic patients

Oral regimens could offer simple solution for severe hyperglycaemia

Digital health: putting patients at the center. An interview with Roz Davies

Videogame addiction may impact sleep habits, obesity and cardio-metabolic health among children and teens

Study shows over-expression of adhesion molecules in fat tissues protects mice from obesity, diabetes

Cancerous lung tumors can alter metabolism by hijacking circadian mechanisms

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