Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Researchers link global increase in type 1 diabetes to advances in medical care

Researchers from the University of Adelaide say the global increase in cases of type 1 diabetes is directly linked to advances in medical care, with the underlying genetics of the disease more likely to be passed from one generation to the next.

6 May 2016

Human milk hormones may play vital role in shaping healthy infant microbiome

A new University of Colorado Anschutz Medical Campus study finds that hormones in breast milk may impact the development of healthy bacteria in infants' guts, potentially protecting them from intestinal inflammation, obesity and other diseases later in life.

5 May 2016

Scientists find that disruption to SCN rhythms can negatively impact overall health

Researchers have shown for the first time how neurons in the SCN are connected to each other, shedding light on this vital area of the brain. Understanding this structure — and how it responds to disruption — is important for tackling illnesses like diabetes and posttraumatic stress disorder. The scientists have also found that disruption to these rhythms such as shifts in work schedules or blue light exposure at night can negatively impact overall health.

4 May 2016

Positive effects of Mediterranean diet on health of elderly population

Sticking to a Mediterranean style diet might slow down ageing finds the EU funded project NU-AGE. At a recent conference in Brussels, researchers presented that a NU-AGE Mediterranean style diet, tested in the project, significantly decreased the levels of the protein known as C-reactive protein, one of the main inflammatory marker linked with the ageing process

3 May 2016

Transplanted human islets provide excellent glycemic control for Type 1 diabetes patients with severe hypoglycemia

Northwestern Medicine researchers are co-investigators in a breakthrough clinical trial that found transplanted human islets prevent hypoglycemic events and provide excellent glycemic control for patients with Type 1 diabetes with severe hypoglycemia. The results of the multi-center, single arm, phase III study are published in Diabetes Care on Monday, April 18. The research was funded by National Institute of Health grants through the National Institute of Allergy and Infectious Diseases and the National Institute for Diabetes and Digestive and Kidney Disease.

3 May 2016

New nanoparticle approach can deliver antiobesity drugs directly to fat tissue

Researchers at MIT and Brigham and Women's Hospital have developed nanoparticles that can deliver antiobesity drugs directly to fat tissue. Overweight mice treated with these nanoparticles lost 10 percent of their body weight over 25 days, without showing any negative side effects.

3 May 2016

Southern Society bestows 2016 Clinical Science Young Investigator Award to Stansfield

Dr. Brian K. Stansfield, neonatologist at Children's Hospital of Georgia and a 2004 graduate of the Medical College of Georgia at Augusta University, has received the 2016 Clinical Science Young Investigator Award from the Southern Society for Pediatric Research.

30 Apr 2016

Study helps discover new treatments for type 2 diabetes in men with low testosterone

Doctors have long known that men with low testosterone are at greater risk for developing type 2 diabetes. For the first time, researchers have identified how testosterone helps men regulate blood sugar by triggering key signaling mechanisms in islets, clusters of cells within the pancreas that produce insulin. The findings, co-authored by Tulane University researchers, are published in the journal

29 Apr 2016

Integrating fiber optic biosensor into microfluidic chip may help in early diagnosis of diabetes

Insulin deficiency and hyperglycemia are two well-known culprits behind diabetes, both of which are reflected in blood glucose concentrations. Now, researchers are working to create ultrasensitive lab-on-a-chip devices to quickly measure glucose concentrations with the goal of developing device for early diagnosis and prevent of diabetes

29 Apr 2016

Dopamine neuron transplants controlled by designer drug may fight Parkinson's disease in mice

A University of Wisconsin-Madison neuroscientist has inserted a genetic switch into nerve cells so a patient can alter their activity by taking designer drugs that would not affect any other cell. The cells in question are neurons and make the neurotransmitter dopamine, whose deficiency is the culprit in the widespread movement disorder Parkinson's disease.

29 Apr 2016

Daily chocolate consumption may improve cardio-metabolic health

A new study published in the British Journal of Nutrition appears to back up the adage that a little of what you fancy does you good.

29 Apr 2016

Study links age-related changes in human pancreas to diabetes development

A Stanford-led national collaboration to procure and analyze human pancreatic tissue from deceased donors illustrates how the organ's function changes as we age, and could point the way toward new diabetes treatments.

29 Apr 2016

Little and often gives exercise benefits in Type 2 diabetes

Sedentary, overweight adults with Type 2 diabetes can improve their cardiometabolic profile by engaging in very brief but regular periods of light walking or resistance exercise, research suggests.

28 Apr 2016

New fruit fly model study reveals metabolic pathway that can be targeted to treat FXS patients

Fragile X syndrome (FXS) is the most common genetically inherited cause of intellectual disability in humans. New research shows how the hormone insulin -- usually associated with diabetes -- is involved in the daily activity patterns and cognitive deficits in the fruitfly model of FXS, according to a new study from the Perelman School of Medicine at the University of Pennsylvania published online this month in Molecular Psychiatry in advance of the print issue.

27 Apr 2016

Clinical inertia puts Type 2 diabetes patients at further risk of preventable complications

People with Type 2 diabetes are being 'let down' because they are being forced to wait for further treatment when needed.

26 Apr 2016

Study reveals how visceral fat contributes to insulin resistance, inflammation

Researchers have long-known that visceral fat - the kind that wraps around the internal organs - is more dangerous than subcutaneous fat that lies just under the skin around the belly, thighs and rear. But how visceral fat contributes to insulin resistance and inflammation has remained unknown.

26 Apr 2016

GLP-1 receptor agonist may benefit high-risk diabetes

Research shows that using a glucagon-like peptide-1 receptor agonist instead of a rapid-acting insulin analogue at mealtimes can reduce glycaemic variability in high-risk patients with Type 2 diabetes.

26 Apr 2016

Nocturnal hypoxemia closely linked to diabetic microvascular complications

Examining the poorly understood link between obstructive sleep apnea (OSA) and type 2 diabetes complications, researchers identified specific measures of low blood oxygenation that are associated with impaired kidney function and diabetic nephropathy.

25 Apr 2016

Scientists uncover molecular identity of previously unknown Glima molecule in Type 1 diabetes

Scientists have solved a decades-old medical mystery by finally identifying a previously unknown molecule which is attacked by the immune system in people with Type 1 diabetes.

25 Apr 2016

Fructose common in western diet can damage brain genes

A range of diseases -- from diabetes to cardiovascular disease, and from Alzheimer's disease to attention deficit hyperactivity disorder -- are linked to changes to genes in the brain. A new study by UCLA life scientists has found that hundreds of those genes can be damaged by fructose, a sugar that's common in the Western diet, in a way that could lead to those diseases.

25 Apr 2016

Insulin News and Research

Further Reading

Researchers link global increase in type 1 diabetes to advances in medical care

Human milk hormones may play vital role in shaping healthy infant microbiome

Scientists find that disruption to SCN rhythms can negatively impact overall health

Positive effects of Mediterranean diet on health of elderly population

Transplanted human islets provide excellent glycemic control for Type 1 diabetes patients with severe hypoglycemia

New nanoparticle approach can deliver antiobesity drugs directly to fat tissue

Southern Society bestows 2016 Clinical Science Young Investigator Award to Stansfield

Study helps discover new treatments for type 2 diabetes in men with low testosterone

Integrating fiber optic biosensor into microfluidic chip may help in early diagnosis of diabetes

Dopamine neuron transplants controlled by designer drug may fight Parkinson's disease in mice

Daily chocolate consumption may improve cardio-metabolic health

Study links age-related changes in human pancreas to diabetes development

Little and often gives exercise benefits in Type 2 diabetes

New fruit fly model study reveals metabolic pathway that can be targeted to treat FXS patients

Clinical inertia puts Type 2 diabetes patients at further risk of preventable complications

Study reveals how visceral fat contributes to insulin resistance, inflammation

GLP-1 receptor agonist may benefit high-risk diabetes

Nocturnal hypoxemia closely linked to diabetic microvascular complications

Scientists uncover molecular identity of previously unknown Glima molecule in Type 1 diabetes

Fructose common in western diet can damage brain genes

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