Genetic News and Research

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New understanding of role of schizophrenia risk gene DISC1 in normal adult brains

How the gene that has been pegged as a major risk factor for schizophrenia and other mood disorders that affect millions of Americans contributes to these diseases remains unclear.

10 Sep 2007

Clearer picture of how a dividing cell rebuilds the nuclear envelope

Just how a dividing cell rebuilds the nuclear envelope, the protective, functional wrapping that encases both the original and newly copied genetic material, has been a source of controversy for the last 20 years.

10 Sep 2007

A chink in bacteria's armor

Biomedical researchers at Boston University's College of Engineering may have discovered the path toward developing better drugs capable of defeating so-called “superbugs,” bacteria that have developed resistance to common antibiotics. The researchers have discovered a previously unknown chain of events occurring in bacteria that opens to door to new avenues of research.

10 Sep 2007

Some with breast cancer stop taking aromatase inhibitors because of joint and muscle pain

More than 10 percent of women with breast cancer stopped taking a commonly prescribed drug because of joint and muscle pain, according to a new study from researchers at the University of Michigan Comprehensive Cancer Center.

10 Sep 2007

Racial disparities in prostate cancer, why?

African-American men face a higher risk of developing prostate cancer in their lifetime, but researchers do not fully understand why.

5 Sep 2007

Ultraconserved elements in the genome: Are they indispensable?

Three years ago, "ultraconserved elements" were discovered in the genomes of mice, rats, and humans.

5 Sep 2007

Antiobesity gene

Researchers have revealed an antiobesity gene that has apparently been keeping critters lean during times of plenty since ancient times.

5 Sep 2007

Adipose gene may be the key to tackle weight

Researchers at UT Southwestern Medical Center have found that a single gene might control whether or not individuals tend to pile on fat, a discovery that may point to new ways to fight obesity and diabetes.

5 Sep 2007

Selection on genes underlying schizophrenia during human evolution

Several genes with strong associations to schizophrenia have evolved rapidly due to selection during human evolution, according to new research in the Proceedings of the Royal Society B (Wednesday 5 September 2007).

5 Sep 2007

Myoendothelial cells identified as new human source of stem cells with potential to repair muscle

For the first time, scientists at Children's Hospital of Pittsburgh of UPMC have discovered a unique population of adult stem cells derived from human muscle that could be used to treat muscle injuries and diseases such as heart attack and muscular dystrophy.

5 Sep 2007

Key differences discovered between avian and human flu

St. Jude scientists have found key features that distinguish influenza viruses found in birds from those that infect humans.

5 Sep 2007

Improved dosing formula for warfarin (Coumadin)

Doctors prescribing blood thinners have had to go through a lengthy trial-and-error process to arrive at the optimal dose for their patients.

5 Sep 2007

Ardea Biosciences completes phase 1 trials of HIV drug RDEA806

Ardea Biosciences, Inc. has announced that it has successfully completed Phase 1 single-ascending-dose, multiple-ascending-dose, food-effect, and drug-interaction studies of RDEA806, a novel HIV non-nucleoside reverse transcriptase inhibitor (NNRTI), in healthy volunteers.

5 Sep 2007

3D fruit fly images to benefit brain research

The fragile head and brain of a fly are not easy things to examine but MRC scientists have figured out how to make it a little simpler. And they hope their research will shed light on human disease.

5 Sep 2007

Muscadine grape skin extract shows promise for prostate cancer

Laboratory experiments show that an extract of the skin of muscadine grapes can inhibit growth of prostate cancer cells in the laboratory.

4 Sep 2007

Hepatitis E virus in Europe

Hepatitis E virus infections can be fatal in pregnant women, but until recently doctors thought the disease was confined to China, India and developing countries.

4 Sep 2007

First individual genome sequence of one person

Independent sequence and assembly of the six billion base pairs from the genome of one person ushers in the era of individualized genomics

4 Sep 2007

Autoimmune response, triggered by genes, can be a barrier to producing a viable offspring

Plant biologists at the Max Planck Institute of Developmental Biology and the University of North Carolina at Chapel Hill have discovered that an autoimmune response, triggered by a small number of genes, can be a barrier to producing a viable offspring.

4 Sep 2007

Adult offspring of parents with PTSD have lower cortisol levels

A small study suggests that adults whose parents are Holocaust survivors with post-traumatic stress disorder (PTSD) appear to have lower average levels of the stress hormone cortisol than the adult offspring of parents without PTSD, according to a report in the September issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

4 Sep 2007

Researchers look at malaria resistance to chloroquine

Funded by a $1.5 million grant from the National Institutes of Health (NIH), scientists at Binghamton University, State University of New York, hope to understand how the malaria parasite Plasmodium falciparum evolved resistance to the once-effective medication chloroquine.

3 Sep 2007