Genetic News and Research

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Promising new line in anti-cancer therapy

A promising new line in anti-cancer therapy by blocking the molecular motors involved in copying genetic information during cell division is being pursued by young Dutch researcher Dr. Nynke Dekker in one of this year's EURYI award winning projects sponsored by the European Science Foundation (ESF) and the European Heads of Research Councils (EuroHORCS).

11 Aug 2007

Scientists find mechanisms controlling metastasis of breast cancer cells

When cancer cells dissociate from the original tumor and migrate via the blood stream to colonize distant organs, is the main cause of cancer death.

9 Aug 2007

Testosterone replacement therapy for men

For decades, older women have taken hormone replacements to replenish estrogen and progesterone levels lost to aging.

9 Aug 2007

Gender differences in renal and other genes contributing to blood pressure

Many common diseases exhibit gender bias and gender differences have been observed in the development of high blood pressure (hypertension) and heart (cardiovascular) disease.

9 Aug 2007

Endothelial nitric oxide synthase gene linked to brain aneurysm formation

University of Cincinnati (UC) neurovascular researchers have identified a gene that, when suppressed or completely absent, may predispose a person to brain aneurysms.

8 Aug 2007

UIC receives $9.6 million grant for autism research

The University of Illinois at Chicago has been awarded a $9.6 million, five-year grant from the National Institutes of Health to establish an Autism Center of Excellence.

7 Aug 2007

Scientists tackle gene doping in athletes

Gene doping has the potential to spawn athletes capable of out-running, out-jumping and out-cycling the strongest of champions.

7 Aug 2007

New research may lead to future gene therapies for patients with sickle cell anemia and beta-thalassemia

Virginia Commonwealth University researchers studying hemoglobin genes, mutations of which play a role in genetic blood disorders like sickle cell anemia and beta-thalassemia, have identified two proteins that are responsible for regulating overlapping groups of genes during the development of red blood cells.

7 Aug 2007

Mother and daughter tackle obesity and diabetes together

Two months ago, Phoenix residents Marlene Zytcer, 57, and her daughter Aimee, 31, traveled to the University of California, San Diego Medical Center for a minimally invasive surgery to lose weight.

7 Aug 2007

Scientists discover the dynamics of transcription in living mammalian cells

Transcription the transfer of DNA's genetic information through the synthesis of complementary molecules of messenger RNA forms the basis of all cellular activities.

7 Aug 2007

Genetic factors strongly shape how peers are chosen

As we develop, the company we keep may be increasingly influenced by our genes, according to a new study led by Virginia Commonwealth University researchers.

7 Aug 2007

Brain areas that control attention thinnest in children with ADHD

Brain areas that control attention were thinnest in children with attention deficit hyperactivity disorder (ADHD) who carried a particular version of a gene in a study by the National Institutes of Health's (NIH) National Institute of Mental Health (NIMH).

7 Aug 2007

ADHD linked to depressed dopamine activity in the brain

Adults with attention-deficit/hyperactivity disorder (ADHD) show a blunted response to the drug methylphenidate (Ritalin), which increases brain dopamine levels, according to a report in the August issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

7 Aug 2007

New insight into mechanism of DNA-break repair

A new UC Davis study that explains the actions of a gene mutation that causes early onset cancer provides a fundamental insight into the mechanism of DNA-break repair.

6 Aug 2007

Ten ALS genes found

Blood samples from more than 220 ALS patients at the Methodist Neurological Institute were used in research that revealed significant changes in or around 10 specific genes in sporadic ALS, the most common form of ALS.

6 Aug 2007

Discovery of mechanism in malaria parasite that helps it adapt to infected individuals

Plasmodium falciparum is responsible for the most severe forms of human malaria.

6 Aug 2007

Ddiscovery of a novel molecular switch offers potential for epilepsy

The discovery of a novel molecular switch that powerfully modulates nerve cell activity offers the potential for new mood disorder and epilepsy treatments, University of California, Irvine researchers report.

6 Aug 2007

Tailor-made antidepressants

In spite that the causes of depression have not still been fully identified, scientists acknowledge that genetic and environmental factors play a common role in the onset of this disorder.

6 Aug 2007

New treatment for glaucoma shows promise

Iowa State University researchers have developed a new technique that successfully treated rats for blindness caused by glaucoma.

3 Aug 2007

Gene fusion subtypes in prostate carcinoma have clinical implications

Building on an earlier study that used Oncomine to identify ETS-fusion proteins in prostate cancer (Science, Oct 28 2005), Tomlins et al. report the identification of four additional classes of ETS rearrangements in prostate cancer, each of which activates ETV1 by a different genetic mechanism (Nature, Aug 2 2007).

3 Aug 2007