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A family of proteins may be able to outwit emerging and re-emerging viruses

A family of proteins best known for their role in diminishing HIV infectivity may have the goods to outwit other emerging and re-emerging viruses, scientists have found.

15 Sep 2021

Deep profiling of SARS-CoV-2 immune response amongst the mildly symptomatic

In a research paper recently uploaded to the medRxiv* preprint server by Capelle et al. (September 2nd, 2021), the immune response of mild and hospitalized COVID-19 patients is compared, finding that early T-cell response is a vital indicator of SARS-CoV-2 disease severity.

15 Sep 2021

UK Sepsis Trust calls for people to better understand the signs and symptoms of sepsis

This World Sepsis Day, the UK Sepsis Trust is calling for people to better understand the signs and symptoms of sepsis and recognize it as a medical emergency, in order to reduce the risk of death and mitigate against the very real long-term health effects of post-sepsis syndrome.

15 Sep 2021

MS patients receiving aCD20 treatment mount robust T-cell responses to COVID-19 vaccines

New research shows that Multiple Sclerosis (MS) patients undergoing anti-CD20 (aCD20) treatment – which depletes the B cells that contribute to the MS attacks – are able to mount robust T-cell responses to the mRNA COVID-19 vaccines, despite having a muted antibody response to the vaccines.

14 Sep 2021

Low dose of Moderna COVID-19 vaccine generates durable immune response

A new study from La Jolla Institute for Immunology (LJI) scientists helps answer the question: how long does immunity against COVID-19 last in vaccinated people?

14 Sep 2021

Severe COVID-19 linked to increase in autoantibodies

Hospitalized COVID-19 patients are substantially more likely to harbor autoantibodies -;antibodies directed at their own tissues or at substances their immune cells secrete into the blood -; than people without COVID-19, according to a new study.

14 Sep 2021

Gut microbiome profile could help predict patient's rheumatoid arthritis prognosis

A significant indicator of whether a patient with rheumatoid arthritis will improve over the course of disease may lie in part in their gut, according to new research from Mayo Clinic's Center for Individualized Medicine.

14 Sep 2021

Family's socio-economic status may influence children's composition of gut microbiome

Findings of a nationwide study led by the Translational Genomics Research Institute, an affiliate of City of Hope, suggest that a family's socio-economic status may influence children's composition of gut microbiome -; the mix of microscopic organisms within the digestive tract.

14 Sep 2021

Age-related differences in immune dynamics in rhesus macaques infected with SARS-CoV-2

In a recent study, authors explore the relationship between age and immune response to COVID-19.

13 Sep 2021

MD Anderson and SNIPR BIOME join forces to advance new CRISPR-based microbiome therapeutics

The University of Texas MD Anderson Cancer Center and SNIPR BIOME today announced a strategic collaboration to advance new CRISPR-based microbiome therapeutics to reduce immune-related adverse events (irAE) in patients being treated with combined immune checkpoint inhibitors.

13 Sep 2021

Study finds possible direct connection between neurodegenerative diseases and the herpesvirus

A new study by researchers at University of Illinois Chicago suggests that when the protein optineurin, or OPTN, is present in cells it restricts the spread of HSV-1, the herpes simplex virus type 1.

13 Sep 2021

Analysis finds untapped potential for immunotherapy in older cancer patients

A retrospective analysis of large datasets of biomarkers from tumors and healthy tissue by researchers at the Johns Hopkins Kimmel Cancer Center Convergence Institute suggests that older cancer patients could benefit as much as younger patients from cancer immunotherapies.

13 Sep 2021

Eosinophils play a role in the battle against cancer metastases, study finds

A new study at Tel Aviv University found that eosinophils - a type of white blood cells - are recruited to the battle against cancer metastases in the lungs.

13 Sep 2021

An oral COVID-19 vaccine induces mucosal and protective immunity

Researchers have collaborated to resolve the aforementioned problems associated with injection vaccines to create a thermostable vaccine that can be taken orally.

13 Sep 2021

Functional impairment of HIV-specific T cells precedes aborted virus control

HIV is a master of evading the immune system, using a variety of methods to prevent the body from being able to find and kill it.

13 Sep 2021

Researchers identify the spleen as primary site for priming of 'killer' T cells during influenza infection

CD8+ T cells -; known as "killer" T cells -; are the assassins of the immune system. Once they are primed, they seek out and destroy other cells that are infected with virus or cells that are cancerous.

12 Sep 2021

Neutrophil extracellular traps boost the bacterial killing power of macrophages

Like a spider trapping its prey, our immune system cells cooperate to capture and "eat" bacteria.

12 Sep 2021

High-dose chemotherapy followed by immunotherapy benefits patients with acute myeloid leukemia

A clinical trial conducted at UNC Lineberger Comprehensive Cancer Center and Johns Hopkins Sidney Kimmel Comprehensive Cancer Center found that high-dose cytarabine followed by subsequent immunotherapy treatment with pembrolizumab benefited patients with resistant or relapsed acute myeloid leukemia (AML), a highly aggressive cancer.

12 Sep 2021

NIH researchers develop a detailed cellular map of chronic MS lesions

Chronic lesions with inflamed rims, or "smoldering" plaques, in the brains of people with multiple sclerosis (MS) have been linked to more aggressive and disabling forms of the disease.

10 Sep 2021

Virus-like nanoparticle vaccine effective against SARS-CoV-2 in animal model

A COVID-19 vaccine, created from a virus-like nanoparticle that displays SARS-CoV-2 spike protein RBDs, effectively protects animal model from infection.

10 Sep 2021

Immune System News and Research

A family of proteins may be able to outwit emerging and re-emerging viruses

Deep profiling of SARS-CoV-2 immune response amongst the mildly symptomatic

UK Sepsis Trust calls for people to better understand the signs and symptoms of sepsis

MS patients receiving aCD20 treatment mount robust T-cell responses to COVID-19 vaccines

Low dose of Moderna COVID-19 vaccine generates durable immune response

Severe COVID-19 linked to increase in autoantibodies

Gut microbiome profile could help predict patient's rheumatoid arthritis prognosis

Family's socio-economic status may influence children's composition of gut microbiome

Age-related differences in immune dynamics in rhesus macaques infected with SARS-CoV-2

MD Anderson and SNIPR BIOME join forces to advance new CRISPR-based microbiome therapeutics

Study finds possible direct connection between neurodegenerative diseases and the herpesvirus

Analysis finds untapped potential for immunotherapy in older cancer patients

Eosinophils play a role in the battle against cancer metastases, study finds

An oral COVID-19 vaccine induces mucosal and protective immunity

Functional impairment of HIV-specific T cells precedes aborted virus control

Researchers identify the spleen as primary site for priming of 'killer' T cells during influenza infection

Neutrophil extracellular traps boost the bacterial killing power of macrophages

High-dose chemotherapy followed by immunotherapy benefits patients with acute myeloid leukemia

NIH researchers develop a detailed cellular map of chronic MS lesions

Virus-like nanoparticle vaccine effective against SARS-CoV-2 in animal model

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