Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Scientists explore new strategies to prevent onset of type 1 diabetes

Type 1 diabetes affects 30,000 individuals throughout Germany and is the most common metabolic disease in children and adolescents. To halt the ever-increasing incidence, the young investigator group "Immunological Tolerance in Type 1 Diabetes" at the Institute of Diabetes Research directed by Prof. Dr. Anette-Gabriele Ziegler is exploring new strategies to prevent the onset of the disease.

16 Mar 2016

Researchers devise synthetic patch filled with insulin-producing beta cells to control blood sugar levels

For decades, researchers have tried to duplicate the function of beta cells, the tiny insulin-producing entities that don't work properly in patients with diabetes. Insulin injections provide painful and often imperfect substitutes. Transplants of normal beta cells carry the risk of rejection or side effects from immunosuppressive therapies.

16 Mar 2016

Orexigen Therapeutics, Valeant Pharmaceuticals sign distribution agreement for Mysimba

Orexigen Therapeutics, Inc. today announced Valeant Pharmaceuticals International, Inc. will commercialize Mysimba (naltrexone HCl / bupropion HCl prolonged release) in Central and Eastern Europe.

15 Mar 2016

Excessive fat accumulation in lower extremities of children linked to insulin resistance, metabolic disorders

Children with a severe type of spina bifida called myelomeningocele have a high prevalence of obesity and excess fat accumulation in their lower extremities. In a study designed to assess bone, muscle and fat tissue distribution in the lower legs of children with this disease, researchers at Children's Hospital Los Angeles determined that this excess fat tissue is within the muscle boundary (muscle-associated) rather than subcutaneous.

15 Mar 2016

Fertility problems put men at increased risk of metabolic diseases

Men with fertility problems are at risk of metabolic diseases as they age, according to work being presented at the European Association of Urology conference in Munich

14 Mar 2016

Scientists explore new treatment avenues to protect obese individuals from cardiovascular disease

Fatness is clearly linked to cardiovascular disease, but scientists want to find why the unhealthy pair tend to go hand-in-hand and how to break up their relationship.

10 Mar 2016

Is the global diet getting sweeter? An interview with Professor Barry Popkin

In the past, caloric sweeteners simply referred to cane sugar or beet sugar. However, over time we've created hundreds of different sugars that are all providing calories of the same amount, about four calories for every gram of the sugar. Some examples include corn syrups and more processed sweeteners like high fructose corn syrup.

10 Mar 2016

Early childhood presents short-lived window for intervention to ensure future cardio-metabolic health

Research conducted at LSU Health New Orleans School of Public Health has found that exposure to poverty does not produce metabolic and inflammatory biomarkers in young, healthy children. It identifies early childhood as an opportunity to prevent a known association in adults between poverty and the metabolic syndrome. The study is one of the first to characterize the timing of exposure to such stress and the emergence of the physiologic changes leading to cardio-metabolic disease and to document these relationships during this critical developmental period.

10 Mar 2016

New discoveries reveal why smokers have increased risk of type 2 diabetes

Researchers at Lund University in Sweden have made two new discoveries with regard to the beta cells' ability to release insulin. The findings can also provide a possible explanation as to why smokers have an increased risk of type 2 diabetes.

9 Mar 2016

Changes in gut bacteria strongly associated with PCOS-related obesity

Modifying gut bacteria could be a treatment option for some of the symptoms associated with the widespread disease polycystic ovary syndrome (PCOS), according to a recent study by San Diego State University researchers in collaboration with investigators from the University of California, San Diego.

8 Mar 2016

Sleeping too much or too little increases risk of dying from heart disease

Too much or too little sleep is linked with an increased risk of certain types of cardiovascular disease. Women and the elderly are particularly at risk.Sleeping less than four hours or more than eight hours a night increases the risk of dying from some types of coronary heart disease, such as heart attacks and unstable angina pectoris, according to a study by Norwegian and Taiwanese researchers.

8 Mar 2016

Healthy aging brings unexpected benefits to pancreatic beta cell function, insulin production

New research shows that a cellular program that causes aging can also bring unexpected benefits in the function of pancreatic beta cells and the production of insulin in mice and humans.

8 Mar 2016

Researchers find new link between elevation of certain amino acids and type 2 diabetes

More than 29 million Americans are currently living with diabetes. The majority have type 2 diabetes, and for them insulin resistance - their body's inability to effectively process sugar - is a part of daily life. Therefore, understanding the cause of insulin resistance is critical to tackling this chronic disease.

8 Mar 2016

Low level of physical fitness in early life associated with Type 2 Diabetes risk in adulthood

The combination of low aerobic capacity and low muscle strength at age 18 is associated with a three times greater risk of developing Type 2 Diabetes in adulthood, according to new research from the Icahn School of Medicine at Mount Sinai published online today in the journal Annals of Internal Medicine.

8 Mar 2016

Absence of PEMT enzyme leads to development of fatty liver disease and tumours in thin patients

Researchers observe protection against obesity and insulin resistance but at the cost of prominent fatty liver disease in mice lacking the PEMT enzyme and patients with low levels of PEMT.

7 Mar 2016

Diets high in glycemic index linked to increased risk of lung cancer

Consuming a diet with a high glycemic index, a classification of how rapidly carbohydrates elevate blood sugar levels, was independently associated with an increased risk of developing lung cancer in non-Hispanic whites, according to a new epidemiologic study from The University of Texas MD Anderson Cancer Center.

4 Mar 2016

P53 genetic variant heavily implicated in metabolism, new research finds

The study may also provide an evolutionary explanation for differences in populations living farther away from the Equator. Human ancestors may have undergone this change in R72 to promote energy storage in cold climates and during times of famine. However, in modern society, the need for this type of variant in our genes is unnecessary, leading instead to increased risk for obesity and type 2 diabetes. Obesity is also a risk factor for certain types of cancer, so these findings may also explain why the R72 variant of p53 might predispose certain people to cancer.

4 Mar 2016

CPAP appears to improve glycemic control in patients with OSA and type 2 diabetes

Continuous positive airway pressure, or CPAP, appears to improve glycemic control in patients with obstructive sleep apnea and type 2 diabetes that is not well controlled, according to research published in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

4 Mar 2016

Drug combination improves glucose control in Type 2 diabetes patients

A multinational clinical trial led by UT Southwestern Medical Center and others found that injection of a new long-acting insulin combined with another drug improves glucose control in patients with Type 2 diabetes and, additionally, is associated with weight loss.

2 Mar 2016

IDegLira injections more effective than traditional insulin injections in treating type-2 diabetes patients

More than two-thirds of all type-2 diabetes patients do not achieve good control of their disease with the first-line medication metformin combined with second-line insulin shots.

2 Mar 2016

Insulin News and Research

Further Reading

Scientists explore new strategies to prevent onset of type 1 diabetes

Researchers devise synthetic patch filled with insulin-producing beta cells to control blood sugar levels

Orexigen Therapeutics, Valeant Pharmaceuticals sign distribution agreement for Mysimba

Excessive fat accumulation in lower extremities of children linked to insulin resistance, metabolic disorders

Fertility problems put men at increased risk of metabolic diseases

Scientists explore new treatment avenues to protect obese individuals from cardiovascular disease

Is the global diet getting sweeter? An interview with Professor Barry Popkin

Early childhood presents short-lived window for intervention to ensure future cardio-metabolic health

New discoveries reveal why smokers have increased risk of type 2 diabetes

Changes in gut bacteria strongly associated with PCOS-related obesity

Sleeping too much or too little increases risk of dying from heart disease

Healthy aging brings unexpected benefits to pancreatic beta cell function, insulin production

Researchers find new link between elevation of certain amino acids and type 2 diabetes

Low level of physical fitness in early life associated with Type 2 Diabetes risk in adulthood

Absence of PEMT enzyme leads to development of fatty liver disease and tumours in thin patients

Diets high in glycemic index linked to increased risk of lung cancer

P53 genetic variant heavily implicated in metabolism, new research finds

CPAP appears to improve glycemic control in patients with OSA and type 2 diabetes

Drug combination improves glucose control in Type 2 diabetes patients

IDegLira injections more effective than traditional insulin injections in treating type-2 diabetes patients

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