Genetic News and Research

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First time observing real-time molecular interplay within ribosome

The ribosome is a kind of factory for protein in the cell, and as such has long been a prime target for drug discovery. Now, a technological advance by a team at Weill Cornell Medical College is poised to revolutionize research in the field.

21 Mar 2007

New dimension to understanding of p53 protein

The p53 protein routinely shuts down damaged cells and is one of our main lines of defence against cancer. Scientists at Karolinska Institutet in Sweden now present new findings on how p53 carries out this all-important function.

21 Mar 2007

Curry related compound shows promise against Kennedy's disease

Scientists who focus on the molecular signaling that underlies prostate cancer have discovered a compound that shows promise against a debilitating neurodegenerative condition known as Kennedy's disease, which is caused by a mutant gene.

21 Mar 2007

Inflammation plays key role in the metastasis of prostate cancer

Many would assume that "mounting an immune response" or "having your body fight the cancer" is a good thing.

19 Mar 2007

Scientists discover new approach for treating virus-induced lymphomas

Kaposi's sarcoma herpesvirus (KSHV) is a human tumor virus and an etiological agent for Kaposi's sarcoma and primary effusion lymphoma (PEL). PELs are aggressive lymphomas with reported median survival time shorter than six months after diagnosis.

19 Mar 2007

FDA clears Xpert EV test for meningitis

The U.S. Food and Drug Administration (FDA) has cleared for marketing a test that uses molecular biology to quickly detect the presence of viral meningitis.

19 Mar 2007

Dramatic increase of Type 1 diabetes in under fives

Researchers are calling for more work in to the reasons behind a big increase of young children with Type 1 diabetes. A new study, led by Bristol University, has discovered that the number of children under five-years-old with Type 1 diabetes has increased five-fold over 20 years.

19 Mar 2007

Scientists decipher a signaling pathway crucially involved in Crohn's disease and ulcerative colitis

Inflammatory bowel diseases, such as Crohn's disease and Ulcerative Colitis, severely impair the lives of more than four million people worldwide. The development of effective therapies against these diseases requires an understanding of their underlying molecular mechanisms.

15 Mar 2007

Researchers uncover genetic sequence responsible for rare form of pancreatic cancer

Pancreatic ductal adenocarcinoma is an almost uniformly fatal disease regardless of the stage at time of diagnosis. However, a small percentage of patients develop a form of ductal adenocarcinoma associated with cystic lesions that can be detected earlier, is less aggressive and has a 50 percent long-term survival rate.

14 Mar 2007

Chemical cues turn embryonic stem cells into cerebellar neurons

Embryonic stem cells have shown a great deal of promise for alleviating heart disease and regenerating organs. But for some of the conditions for which people hold out the most hope - Alzheimer's and Parkinson's, for example - there's been little evidence to date that stem cells can work.

14 Mar 2007

Gene and a region of a chromosome identified that may lead to autism in children

Yale School of Medicine autism experts Fred Volkmar, M.D. and Ami Klin are part of a global research consortium from 19 countries to identify a gene and a region of a chromosome that may lead to autism in children.

13 Mar 2007

Novel pathway for antibiotic-induced cell death

Scientists have identified unforeseen mechanisms by which quinolones - a family of broad-spectrum antibiotics among the most widely prescribed - induce bacterial cell death.

13 Mar 2007

New method for identifying viruses and bacteria that cause common infections in children

Infectious disease specialists at UT Southwestern Medical Center have found a new method for identifying suspect viruses and bacteria that cause some of the most common acute infections in children.

13 Mar 2007

Stem cells delay neurodegeneration in the brain

Sufferers from devastating neurodegenerative diseases have been given some hope by the results of recent research.

12 Mar 2007

New discovery suggests novel methods for treating acute lymphoblastic leukemia

Investigators at St. Jude Children's Research Hospital have discovered previously unsuspected mutations that contribute to the formation of pediatric acute lymphoblastic leukemia (ALL), the most common cancer in children.

8 Mar 2007

HIV-positive men who have sex before circumcision wounds are healed could increase female partners' infection risk

HIV-positive men undergoing circumcision might be more likely to transmit the virus to their female partners if they have sex before the circumcision wounds have healed, according to preliminary results from a study being conducted in Uganda and presented on Tuesday to 75 officials from the World Health Organization and UNAIDS at a meeting in Montreux, Switzerland, the Washington Post reports

8 Mar 2007

China's southern Guangdong Province found to be source of H5N1

A team of scientists at the University of California, Irvine, who have been conducting a genetic analysis of the H5N1 bird flu virus, have found that China's southern Guangdong Province is the source of the deadly strain.

7 Mar 2007

Gene tests and brain imaging reveal early dementia

Dementia diseases develop insidiously and are generally discovered when the memory has already started to deteriorate. New research form Karolinska Institutet shows, however, that approaching Alzheimer's can be detected several years before the symptoms manifest themselves.

6 Mar 2007