Genetic News and Research

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Simple diagnostic test detects genetic signs of lung cancer in sputum

DNA coughed up along with phlegm could point to lung cancer, say researchers at the University of Maryland School of Medicine who are developing an inexpensive and non-invasive gene probe to help diagnose early stage lung cancer in current and former smokers.

18 Jan 2007

Lung neutrophils produce histamine in significant quantities

In a surprise finding, scientists have discovered that histamine, the inflammatory compound released during allergic reactions that causes runny nose, watery eyes, and wheezing, can be produced in large amounts in the lung by neutrophils, the white blood cells that are the major component of pus.

14 Jan 2007

Variations in SORL1 gene may factor in development of Alzheimer's disease

Variations in a gene known as SORL1 may be a factor in the development of late onset Alzheimer's disease, an international team of researchers has discovered. The genetic clue, which could lead to a better understanding of one cause of Alzheimer's, is reported in Nature Genetics online, and was supported in part by the National Institutes of Health (NIH).

14 Jan 2007

Stem cell research discovery could mean 'big things' for cancer

A new discovery in stem cell research may mean big things for cancer patients in the future. Gary Van Zant, Ph.D., and a research team at the University of Kentucky published their findings in Nature Genetics.

14 Jan 2007

Retinoblastoma gene may play a critical role in the development of the placenta

An important cancer-related gene may play a critical role in the development of the placenta, the organ that controls nutrient and oxygen exchange between a mother and her fetus during pregnancy, and perhaps in miscarriages.

10 Jan 2007

New approach offers hope for an effective herpes vaccine

A researcher at Montana State University has called for an innovative, new approach in developing a vaccine against genital herpes.

10 Jan 2007

Emory University announces new health institute

Emory University announced today a new Global Health Institute that will help address the most pressing health challenges around the world, particularly in poorer nations.

10 Jan 2007

Stem cells derived from human amniotic fluid appear to offer many of the benefits of embryonic stem cells

...including the ability to grow into brain, muscle, bone and other tissues -- according to a study published in the Jan. 7 online edition on the journal Nature Biotechnology, the Washington Post reports.

9 Jan 2007

Several specific genetic alterations associated with development of smoking-related cancers

Preliminary research indicates that several specific genetic alterations are associated with the development of smoking-related head and neck skin cancers, according to a report in the January 10 issue of JAMA: The Journal of the American Medical Association.

9 Jan 2007

New hope for Krabbe disease sufferers

By all expectations, it shouldn't have worked as well as it did. A combination of bone marrow transplantation and gene therapy greatly lengthened the lives of laboratory mice doomed by a rapidly progressing, fatal neurodegenerative disorder also found in people.

9 Jan 2007

Test to detect drug-resistant HIV strains could help provide earlier treatment

A test to detect drug-resistant HIV strains in people with low levels of drug-resistant viral loads could help physicians provide more effective treatment earlier to HIV-positive people, according to a study published on Sunday in the online edition of the journal Nature Methods, BBC News reports.

9 Jan 2007

TrkB and its role in learning and memory

For the first time researchers investigate the molecular basis of memory in living mice.

9 Jan 2007

Dark state and DNA

Chemists at Ohio State University have probed an unusual high-energy state produced in single nucleotides - the building blocks of DNA and RNA - when they absorb ultraviolet (UV) light.

9 Jan 2007

Retinoblastoma gene may play a critical role in the development of the placenta

9 Jan 2007

Specific gene found that protects some people with diabetes from severe kidney failure

A research team at Wake Forest University Baptist Medical Center and the University of Heidelberg has proven that a gene protects some people with diabetes from developing severe kidney failure or "end-stage renal disease."

9 Jan 2007

A fully integrated microfluidic genetic analysis system with sample-in-answer-out capability

In an accomplishment that represents a significant step toward an era of rapid, inexpensive, bedside testing for cancer, researchers at the University of Virginia have developed a microfluidic device that can process human blood samples and yield diagnostic results within an hour.

8 Jan 2007

DNA vaccine for H5N1 avian influenza enters human trial

The first human trial of a DNA vaccine designed to prevent H5N1 avian influenza infection began on December 21, 2006, when the vaccine was administered to the first volunteer at the National Institutes of Health (NIH) Clinical Center in Bethesda, MD.

3 Jan 2007

Men who father only daughters have a higher risk of prostate cancer

In a new and unique study to determine if genes on the Y chromosome are involved in prostate cancer, researchers at Columbia University's Mailman School of Public Health in conjunction with Hebrew University of Jerusalem found that men who had only daughters had a higher risk of prostate cancer than men who had at least one son, thus signifying a possible defect on the father's Y chromosome.

3 Jan 2007

Bulimia may result from hormonal imbalance

Bulimia is normally regarded as a mental illness that should be treated with cognitive behavioural therapy (CBT).

3 Jan 2007

Renegade ribonucleic acid

Researchers at Johns Hopkins have discovered that a tiny piece of genetic code apparently goes where no bit of it has gone before, and it gets there under its own internal code.

3 Jan 2007