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Inhibiting a particular cancer-causing gene improves radiation effectiveness

Inhibiting a particular cancer-causing gene can enhance the cell-killing effects of radiation, a team of radiation oncologists and cancer biologists at the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia has found.

8 Nov 2006

Phase I clinical trial of experimental gene therapy to treat HIV shows encouraging results

The results of a Phase I clinical trial of an experimental gene therapy aimed at treating HIV indicate that the therapy is safe and effective and also might sustain viral loads, according to a study published on Monday in the online edition of the Proceedings of the National Academy of Sciences, the AP/Washington Post reports.

8 Nov 2006

Chronic fatigue syndrome begins with childhood trauma and stress

According to the latest research traumatic events in childhood, and stress or emotional instability at any period in life, may be linked to the development of chronic fatigue syndrome (CFS).

8 Nov 2006

UIC study evaluates two medications for ADHD

University of Illinois at Chicago researchers are comparing two drugs commonly used to treat attention deficit hyperactivity disorder to determine if genetic factors predict which children will respond to either or both drugs.

7 Nov 2006

New evidence says SIDS caused by abnormality in the brainstem

According to a new study by researchers in the U.S. some babies who die from sudden infant death syndrome (SIDS) do so because of an abnormality in the serotonin system in their brains.

1 Nov 2006

Chinese lack of transparency could trigger bird flu pandemic

The transparency of health authorities in China has come under criticism yet again with the news of a new strain of the deadly H5N1 bird flu virus which virologists say could be resistant to vaccines.

1 Nov 2006

Potential for first diagnostic DNA test to guide antidepressant treatment

Treatment of depression is difficult for both patients and for psychiatrists. While there are numerous drugs available that work, finding the right one -- or right combination -- is, at times, a matter of trial and error.

31 Oct 2006

Effective test for screening Huntington's disease drugs

A test using cultured cells provides an effective way to screen drugs against Huntington's disease and shows that two compounds - memantine and riluzole - are most effective at keeping cells alive under conditions that mimic the disorder, UT Southwestern Medical Center researchers report.

30 Oct 2006

Amgen, Brigham and Women's Hospital, NIH to launch women's health genome study

Biotechnology company Amgen, Boston-based Brigham and Women's Hospital and NIH plan to launch the Women's Health Genome Study -- which aims to discover the genetic causes of disorders affecting women, including breast cancer -- the Wall Street Journal reports.

24 Oct 2006

Boston Globe examines the funding approach of the Bill and Melinda Gates Foundation

The Boston Globe on Sunday examined the funding approach of the Bill & Melinda Gates Foundation, which has a $31.9 billion endowment and a commitment of $30 billion from Berkshire Hathaway Chair Warren Buffett.

24 Oct 2006

Benign virus previously used as a marker in tracing human migration may be unreliable

...according to researchers at Penn State. Results of this study also suggest that some viruses might be undergoing much higher rates of evolution than previously thought.

24 Oct 2006

Racial disparities exist in pulmonary hypertension mortality and morbidity

African-American women have the highest mortality rate for idiopathic pulmonary arterial hypertension (IPAH), according to new research.

24 Oct 2006

ODC genetic variation impacts aspirin's effectiveness in preventing colon cancer

Dartmouth researchers are among a team of doctors that have learned more about how people may or may not benefit from taking aspirin in the effort to curb colon cancer.

24 Oct 2006

New study emphasizes the importance of metabolomics to the advent of personalized medicine

International experts have collaborated on a comprehensive collection of reviews focusing on the emerging interface between metabolomics and pharmacogenomics.

24 Oct 2006

Researchers uncover new way in which the aging process is linked to DNA damage

Researchers have uncovered a new way in which the aging process is linked to DNA damage--which occurs normally as a result of cell metabolism and environmental influences--and the various ways in which cells repair that damage.

23 Oct 2006

Further European investment in genomics

The Economic and Social Research Council (ESRC) has announced continued funding, from 2007 to 2012, for its three research centres, CESAGen, EGENIS and INNOGEN, that, along with the ESRC Genomics Policy and Research Forum, make up the ESRC Genomics Network.

23 Oct 2006

Evolutionary connection between food supply and brain size

In a study of orangutans living on the Indonesian islands of Borneo and Sumatra, scientists from Duke University and the University of Zurich have found what they say is the first demonstration in primates of an evolutionary connection between available food supplies and brain size.

23 Oct 2006

Common gene variant increases risk of developing diabetes

Carrying two copies of a common variant of a particular gene doubles your chances of developing diabetes and puts you in a similar risk category to being clinically obese, according to a collaborative study led by UCL (University College London) researchers.

23 Oct 2006

Eye color reflects a simple, predictable and reliable genetic pattern of inheritance

Before you request a paternity test, spend a few minutes looking at your child's eye color. It may just give you the answer you're looking for.

23 Oct 2006

Race is associated with unfavorable breast cancer tumor biology

African-American women with breast cancer were more likely to have larger, later-stage tumors that were more difficult to treat and also had lower survival rates than Hispanic and Caucasian women who received the same treatment in two independent series of clinical trials examined by researchers from The University of Texas M. D. Anderson Cancer Center.

23 Oct 2006