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Eliminating ABCB5-expressing cells crucial for successful colorectal cancer treatment

Researchers at Children's Hospital Boston have found a marker called ABCB5 that both tags a small proportion of cells within colorectal cancers and fuels resistance in those cells to standard treatments. The results indicate that eliminating ABCB5-expressing cells is crucial for successful colorectal cancer treatment, while adding to the growing body of evidence for a theory of cancer growth called the cancer stem cell hypothesis.

9 Jun 2011

Medical management preferred over surgery for pediatric orbital cellulitis

Researchers from Hasbro Children's Hospital in Providence, R.I., report that medical management may be preferred over surgery for children with orbital cellulitis, an acute infection of the tissues surrounding the eye. They have determined the criteria for surgical intervention should be dependent upon the size of a subperiosteal abscess (SPA).

9 Jun 2011

State roundup: N.J. plan would cut Medicaid by $500 million

States and territories are eligible for up to $40 million to strengthen and coordinate efforts to prevent chronic disease, the Health and Human Services Department announced Tuesday. The initiative is funded by the healthcare reform law and targets the nation's five leading chronic diseases: heart disease, cancer, stroke, diabetes and arthritis.

9 Jun 2011

Valuable insight into how people develop B-cell lymphoma

Researchers from the University of Sheffield have discovered valuable insight into how people develop B-cell lymphoma, one of the most common cancers in the UK.

9 Jun 2011

Autism caused by hundreds of different genetic mutations: Study

New research shows that autism is not caused by one or two gene defects but probably by hundreds of different mutations, many of which arise spontaneously. This comes from the study that has examined the genes of more than 1,000 families.

9 Jun 2011

Scientists, advocacy experts form new international Foundation for Vaccine Research

Fourteen leading scientists and advocacy experts in vaccines and infectious diseases have announced the formation of a new international Foundation to advance and accelerate vaccine research and development against infectious diseases.

9 Jun 2011

Childhood trauma linked to higher rates of mental health problems and obesity, says Stanford/Packard psychiatrist

New research has shown that children’s risk for learning and behavior problems and obesity rises in correlation to their level of trauma exposure, says the psychiatrist at the Stanford University School of Medicine and Lucile Packard Children’s Hospital who oversaw the study. The findings could encourage physicians to consider diagnosing post-traumatic stress disorder rather than attention deficit/hyperactivity disorder, which has similar symptoms to PTSD but very different treatment.

8 Jun 2011

UAB first in U.S. with cell-processing workstation

The University of Alabama at Birmingham has taken a significant step toward making sophisticated cell therapy a part of patient care with its acquisition of the first cell-processing workstation (CPWS) from SANYO North America Corporation (SANYO) in the United States.

8 Jun 2011

Drop in flu vaccination rates alarms health authorities

According to latest figures the number of young children vaccinated against the flu in WA this year has plummeted almost 80 per cent. This is concerning for health officials who believe that parents have been scared off by last year's spate of seizures after the jabs.

8 Jun 2011

Survey reveals differences in weight-related counseling among medical specialties

Fewer than half of primary care physicians for adults talk to their patients about diet, exercise and weight management consistently, while pediatricians are somewhat more likely to do so, according to two new studies.

8 Jun 2011

New journal on multiple sclerosis and related disorders

Elsevier, a world-leading provider of scientific, technical and medical information products and solutions, is pleased to announce the launch of a new journal, Multiple Sclerosis and Related Disorders with its first issue publication in January 2012.

8 Jun 2011

NYU Cancer Institute scientists present new research findings at ASCO 2011

Experts from The Cancer Institute, an NCI-designated cancer center, at NYU Langone Medical Center presented new research findings at the 47th American Society of Clinical Oncology (ASCO) 2011 Annual Meeting in Chicago, IL.

8 Jun 2011

Withdrawal of aid from Madagascar hitting poor hard

The Guardian's "Poverty Matters Blog" examines the effects of the withdrawal of international aid and debt relief from Madagascar following the country's last coup in 2009. According to the article, "80% of the population is classed as living in poverty. A household survey last year by the United Nations Children's Fund (Unicef) found that aid sanctions are biting the wrong people: school enrolment has plummeted and health indicators are in decline."

8 Jun 2011

New research on spinal muscular atrophy

Spinal muscular atrophy (SMA) is the leading genetic cause of death in children under 2, with no treatment other than supportive care. In the Proceedings of the National Academy of Sciences, researchers at Children's Hospital Boston show how loss or mutation of the SMA gene causes progressive muscle degeneration and weakness, and suggest a promising approach to treating the condition, sometimes referred to as a "Lou Gehrig's disease of babies."

8 Jun 2011

Closed-loop artificial pancreas could fight against Type 1 diabetes

Engineering researchers at Rensselaer Polytechnic Institute are combining automation techniques from oil refining and other diverse areas to help create a closed-loop artificial pancreas. The device will automatically monitor blood sugar levels and administer insulin to patients with Type 1 diabetes, and aims to remove much of the guesswork for those living with the chronic disease.

8 Jun 2011

New book explores food and eating habits among prehistoric people

From the paleolithic diet to the raw food diet, many health-conscious Americans now want to eat the way they believe our ancient ancestors ate.

8 Jun 2011

Maternal-child health disparities need to be addressed in the U.S., says expert

Despite billions of dollars spent on health care each year, the United States ranks 27th out of 33 developed countries for life expectancy at birth. Leading causes of infant mortality are complications related to pre-term birth or low birth weight-outcomes that have been linked with domestic violence.

8 Jun 2011

GAVI appeals for $3.7B ahead of pledging conference despite lower vaccine prices

The GAVI Alliance has appealed to donors for $3.7 billion to be pledged during an upcoming conference despite announcements by several major pharmaceutical companies to lower the prices of their vaccines for childhood diseases, the Associated Press/Washington Post reports.

8 Jun 2011

Lethal malaria parasite has biochemical weakness

Every year, 10,000 pregnant women and up to 200,000 newborn babies are killed by the malaria parasite. Doctors all around the globe have for years been looking in vain for a medical protection, and now researchers from the University of Copenhagen have found the biochemically weakness of the lethal malaria parasite, and will now start developing a vaccine to combat pregnancy related malaria.

8 Jun 2011

Women who gain excessive weight during pregnancy may have newborns with high body fat

Women who gain too much weight during pregnancy tend to have newborns with a high amount of body fat, regardless of the mother's weight before pregnancy, a new study finds. The results will be presented Tuesday at The Endocrine Society's 93rd Annual Meeting in Boston.

8 Jun 2011