Genetic News and Research

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Genetic analysis of opioid-induced hyperalgesia

In findings published in Nature Biotechnology (May 2006, vol. 24 No. 5), Roche scientists present a new method for analyzing the metabolism of a commonly prescribed drug.

10 May 2006

Breast cancer may be on the rise in U.S.-based Latinas

Breast cancer is an understudied and poorly understood disease in Hispanic/Latina populations in the U.S., and breast cancer appears to be presenting at an earlier age in this population, on average 10 years younger when compared to Caucasian women.

10 May 2006

"Junk" RNA regulates important cellular processes

It has been known for a long time that much of a cell’s RNA stems from DNA regions called intergenic spacers (IGS) that lie between two genes and do not code for proteins.

9 May 2006

Aggressive cancer treated successfully in mice

White blood cells from a strain of cancer-resistant mice cured advanced cancers in ordinary laboratory mice, researchers at Wake Forest University School of Medicine reported.

9 May 2006

New discovery about role of sugar in cell communication

A research team from Uppsala University has uncovered an entirely new mechanism for how communication between cells is regulated.

9 May 2006

Europe wide study to examine causes of asthma

The GABRIEL project, funded through an EC Framework 6 grant, involves over 150 scientists from 14 European countries and Russia, using the latest research across a variety of disciplines, including genetics, epidemiology and immunology, to identify key factors in the development of asthma bronchiale.

9 May 2006

Ethnic differences in risks of adverse reactions to drugs used in cardiovascular medicine

Some ethnic groups may be more susceptible to adverse drug reactions, finds a study published online in the British Medical Journal.

9 May 2006

Summer sun safety - research reveals significant link to melanoma

Fifty years of medical studies show that sun exposure is a primary component in the development of melanoma, the most serious and deadly type of skin cancer, report leading dermatologists in the April 2006 issue of Dermatologic Surgery.

9 May 2006

Effective gene suppression using small interfering RNA in hard-to-transfect human T cells

A technical advance in laboratory techniques may provide biology researchers broader access to RNA interference, a process of blocking the activity of targeted genes. RNA interference has recently emerged as an important tool in studying how genes function in normal biological processes and in disease.

9 May 2006

Scientists discover molecular security mechanism for keeping gene mutations in check

Everyone knows mutations - genetic mistakes in DNA, the material of heredity - are bad: The more mutations in the cell's DNA, the higher the risk of cancer developing.

8 May 2006

NYU pediatric neurosurgeon reports on 25 children with tuberous sclerosis

Sadly, none of the treatments for epilepsy - anti-seizure medications, a procedure called vagus nerve stimulation, a special diet - could quell the electrical storms in the young boy's brain.

8 May 2006

New understanding of chromosomal glue

Researchers have a new understanding of the process cells use to ensure that sperm and eggs begin life with exactly one copy of each chromosome - a process that must be exquisitely regulated to prevent problems such as miscarriages and mental retardation.

8 May 2006

Gene mutation associated with deafness can play an important part in wound healing

A mutation in a gene commonly associated with deafness can play an important part in improving wound healing, a scientist told the annual conference of the European Society of Human Genetics in Amsterdam, The Netherlands.

8 May 2006

A pericellular collagenase directs the 3-D development of white adipose tissue

In the journal Cell, researchers report the serendipitous discovery that the initial development of fat requires a "remodeling" protein that must first make way for the lipid-laden tissue's growth.

8 May 2006

Allergy-free soybeans

Researchers have isolated two Chinese soybean lines that grow without the primary protein linked to soy allergies in children and adults.

8 May 2006

New approaches to genetic disease, based on cells' own ability to correct themselves

New approaches to genetic disease, based on cells' own ability to correct themselves, will be outlined today at the annual conference of the European Society of Human Genetics in Amsterdam, The Netherlands.

8 May 2006

Discovery of gene that appears to play an important role in the onset of type 2 diabetes

In a painstaking set of experiments in overweight mice, scientists from the University of Wisconsin-Madison have discovered a gene that appears to play an important role in the onset of type 2 diabetes.

8 May 2006

MicroCT-based virtual histology

Utah and Texas researchers combined miniature medical CT scans with high-tech computer methods to produce detailed three-dimensional images of mouse embryos - an efficient new method to test the safety of medicines and learn how mutant genes cause birth defects or cancer.

8 May 2006

Mutated gene leads to JSRD

The research team, directed by Joseph Gleeson, M.D., Director of the Neurogenetics Laboratory at the UCSD School of Medicine and associate professor in the Department of Neurosciences, have identified a new gene that, when mutated, leads to JSRD. Their findings will be published on-line in advance of publication in the journal Nature Genetics.

8 May 2006

New technique for freezing and preserving genetically enhanced pig embryos

Researchers led by a University of Missouri-Columbia professor of reproductive biotechnology have reported success in freezing and preserving swine embryos that were created by in vitro techniques and that carried modified genetic material.

3 May 2006