Genetic News and Research

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New technique for freezing and preserving genetically enhanced pig embryos

Researchers led by a University of Missouri-Columbia professor of reproductive biotechnology have reported success in freezing and preserving swine embryos that were created by in vitro techniques and that carried modified genetic material.

3 May 2006

Researchers pinpoint autism's genetic roots

By deleting a gene in certain parts of the brain, researchers at UT Southwestern Medical Center have created mice that show deficits in social interaction that are reminiscent of humans with autism spectrum disorders.

3 May 2006

Combination of genetic mutation and viral infection may cause prostate cancer

Significant recent interest in the literature (JAMA 2006;295:1503, Lancet, epub) and by patients has arisen in response to a presentation given by Dr. Eric Klein of the Cleveland Clinic at the 2006 Prostate Cancer Symposium in San Francisco, February 24, 2006.

3 May 2006

Therapeutic gene suspected to cause cancer

One of the few gene therapy studies that had ever been successful was terminated in 2003, because several of the treated children had developed leukemia.

3 May 2006

Differential effects of HOXB4 on nonhuman primate short and long-term repopulating cells

Transplantation of hematopoietic stem cells (HSCs, the cells that can give rise to all blood and most immune cell types) can save patients whose own hematopoietic system is defective or has been destroyed (often through radiation or chemotherapy of cancer).

3 May 2006

Very young infants are much more capable of organising their visual world than previously thought

Research investigating attention in infancy has revealed that, at just four months old, babies are able to organise visual information in at least three different ways, according to brightness, shape, and how close the visual elements are together (proximity).

3 May 2006

Polyunsaturated fat and vitamin E halves risk of developing motor neurone disease

A high dietary intake of polyunsaturated fat and vitamin E seems to halve the risk of developing motor neurone disease, suggests research published in the Journal of Neurology Neurosurgery and Psychiatry.

3 May 2006

Compensation by tumor suppressor genes during retinal development in mice and humans

Humans are more susceptible to developing the eye cancer retinoblastoma than mice because, unlike humans, mice can compensate for the loss of activity of a gene critical to normal retinal development, according to results of a study by investigators at St. Jude Children's Research Hospital.

3 May 2006

Scientists create leaner and meaner E. coli

By stripping the E. coli genome of vast tracts of its genetic material - hundreds of apparently inconsequential genes - a team of Wisconsin researchers has created a leaner and meaner version of the bacterium that is a workhorse of modern biology and industry.

3 May 2006

Traffic, susceptibility and childhood asthma

Young children who live near a major road are significantly more likely to have asthma than children who live only blocks away, according to a study that appears in Environmental Health Perspectives.

3 May 2006

Identification of CPT1c gene that the brain needs to manage body weight

Working with genetically engineered mice, Johns Hopkins scientists have interfered with the brain's ability to control an animal's response to a high-fat diet.

3 May 2006

Men find masculine men more threatening during their partner's ovulation phase

Men become more jealous of dominant males when their female partner is near ovulation, researchers at the University of Liverpool have found.

3 May 2006

Scientists discover a master key to microbes' pathogenic lifestyles

For some microbes, the transformation from a benign lifestyle in the soil to that of a potentially deadly human pathogen is just a breath away.

3 May 2006

Environmentally damaged DNA may contribute to human genetic diversity

In this month's issue of the leading scientific journal Genome Research, scientists from Kyushu University report how environmentally damaged DNA may contribute to human genetic diversity.

2 May 2006

Genetic and environmental factors impact chronic fatigue syndrome patients

People who suffer from chronic fatigue syndrome (CFS) have a genetic make up that affects the body's ability to adapt to change, according to a series of papers released last week by the Centers for Disease Control and Prevention (CDC).

2 May 2006

Study investigates early biology of HIV infection

In July 2005, the race to find a vaccine that would stem the worldwide rate of 13,000 new cases of HIV infection each day moved from competition among research institutions to a strategy of cooperation.

2 May 2006

New approach to treating breast cancer uses existing chemo drug

British scientists say women who develop breast cancer because of two common genetic mutations could have their treatment transformed by a chemotherapy drug which already exists.

1 May 2006

New drug to treat rare Pompe disease gets FDA approval

The Food and Drug Administration in the U.S. has given approval for the first drug to treat a rare, debilitating muscle disease that can kill infants within a year.

1 May 2006

New method could predict individual patient responses to drug treatments

Scientists from Imperial College London and Pfizer have developed a new method that could predict individual patient responses to drug treatments. The authors anticipate that the development will advance biomedical research further towards development of personalised medicines.

28 Apr 2006

Amyloid protein content in the brain linked to Alzheimer's disease risk

Researchers from the Flanders Interuniversity Institute for Biotechnology (VIB) connected to the University of Antwerp are the first to show that the quantity of amyloid protein in brain cells is a major risk factor for Alzheimer's disease. Amyloid protein has already been known to be the primary component of the senile plaques in the brains of patients. The new discovery demonstrates that the greater the quantity of the protein that is produced, the younger the dementia patient is.

28 Apr 2006