Androgen News and Research

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New study describes unique role of androgens in kidney cancer

A new study is believed to be the first to describe the unique role of androgens in kidney cancer, and it suggests that a new approach to treatment, targeting the androgen receptor (AR), is worth further investigation.

13 Oct 2017

UIC study receives $3 million federal grant to study effects of inflammation on PCOS

The University of Illinois at Chicago has received a $3 million federal grant to study the effects of inflammation on polycystic ovary syndrome, or PCOS.

10 Oct 2017

Scientists unravel mechanism that links gut bacteria to hypertension

One in three American adults suffers from high blood pressure, or hypertension. The disease can be passed down in families, and certain lifestyle factors such as smoking, high-sodium diets, and stress can increase the risk.

3 Oct 2017

New study reveals impact of Agent Orange exposure on women and babies in Vietnam

Exposure to Agent Orange sprayed during the Vietnam War has been linked to increased levels of certain hormones in women and their breastfeeding children decades later, potentially putting them at higher risk of health problems, according to a new study in Science of the Total Environment.

26 Sep 2017

NIH awards $15 million to develop 3D microphysiological system platforms that model human disease

More than 60 percent of investigational drugs fail in human clinical trials due to a lack of effectiveness, despite promising pre-clinical studies using cell and animal research models.

13 Sep 2017

Phthalate levels in expectant fathers influence sperm epigenetics, study suggests

Early results from a larger, ongoing study led by environmental health scientist Richard Pilsner at the University of Massachusetts Amherst suggest that phthalate levels in expectant fathers have an effect on couples' reproductive success via epigenetic modifications of sperm DNA.

12 Sep 2017

Two new treatments may benefit patients with high risk prostate cancer, trial shows

Patients with high risk prostate cancer starting long-term hormone therapy may benefit from two new treatments, according to late-breaking results from the STAMPEDE trial presented at the ESMO 2017 Congress in Madrid.

8 Sep 2017

Bariatric surgery in men linked to frequent sperm aberrations and lower fertility rates

A meta-analysis of studies in which men underwent Roux-en-Y gastric bypass (RYGB) procedures found frequent sperm aberrations and lower fertility rates despite improvements in weight, androgen levels, and sexual quality of life following the procedure.

8 Sep 2017

Women with PCOS have higher risk of developing type 2 diabetes, study reveals

Women who have polycystic ovary syndrome (PCOS) have a higher risk of developing type 2 diabetes (T2D) and are diagnosed at an earlier age with the condition, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

29 Aug 2017

New blood test can predict drug resistance in patients with advanced prostate cancer

When bacteria develop antibiotic resistance, treatment with these medications becomes ineffective. Similarly, tumor cells can also change in such a way that renders them resistant to particular medications.

22 Aug 2017

NIH researchers unravel how male, female mouse embryos acquire sex-specific reproductive systems

A protein called COUP-TFII determines whether a mouse embryo develops a male reproductive tract, according to researchers at the National Institutes of Health and their colleagues at Baylor College of Medicine, Houston.

17 Aug 2017

Mice study shows why women with obesity have more aggressive breast cancer

Women with obesity are more likely to get breast cancer, and a number of studies have provided a reasonable explanation why: after menopause, fat tissue manufactures estrogen, and the estrogen then promotes tumor growth.

8 Aug 2017

Researchers provide evidence supporting need for gender-specific anti-inflammatory drugs

Perhaps you have come across the titles 'Men are from Mars, women are from Venus' or 'Why men don't listen and women can't read maps': just two of the many books and articles -- some enlightening or amusing and others irritating -- that theorise about fundamental differences between men and women.

26 Jul 2017

Excess male hormones in PCOS women contribute to metabolic complications, study shows

Scientists from the University of Birmingham have discovered the link between increased male hormones and metabolic complications such as diabetes and fatty liver disease in patients with polycystic ovary syndrome.

23 Jun 2017

Moffitt researchers develop novel drug that may help combat castration-resistant prostate cancer

Prostate cancer is the third most common cause of cancer-related death in men in the United States. It is estimated that 161,360 men will be diagnosed and more than 26,700 men will die from the disease in this year.

12 Jun 2017

Study explores effects of androgen deprivation therapy on overall geriatric health

Androgen drives many prostate cancers. But the body uses androgen for muscle growth and maintenance, among other functions.

5 Jun 2017

Standard therapy plus abiraterone lowers relative risk of death in men with advanced prostate cancer

A clinical trial of nearly 2,000 men shows that adding abiraterone acetate (Zytiga) to a standard initial treatment regimen for high-risk, advanced prostate cancer lowers the relative risk of death by 37%.

5 Jun 2017

Precise delivery of HDR brachytherapy provides good quality of life to prostate cancer patients

Doctors have found that treating prostate cancer with a single, high dose of radiation delivered precisely to the site of the tumor results in good quality of life and fewer trips to the hospital, with adverse side effects that are no worse than if the radiation treatment had been given in several lower doses.

8 May 2017

Molecular mechanism reprograms tumor cells to drive treatment resistance in advanced prostate cancer

Columbia University Medical Center researchers have discovered a molecular mechanism that reprograms tumor cells in patients with advanced prostate cancer, reducing their response to anti-androgen therapy.

4 May 2017

Combined treatment regimen shows early promise in eliminating metastatic prostate cancer

In the past, all forms of metastatic prostate cancer have been considered incurable. In recent years, the FDA has approved six drugs for men with metastatic disease, all of which can increase survival.

18 Apr 2017