Radiation Therapy News and Research

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Radiation therapy (also called radiotherapy, x-ray therapy, or irradiation) is the use of a certain type of energy (called ionizing radiation) to kill cancer cells and shrink tumors. Radiation therapy injures or destroys cells in the area being treated (the “target tissue”) by damaging their genetic material, making it impossible for these cells to continue to grow and divide. Although radiation damages both cancer cells and normal cells, most normal cells can recover from the effects of radiation and function properly. The goal of radiation therapy is to damage as many cancer cells as possible, while limiting harm to nearby healthy tissue.

Cell survival protein could protect kidneys from damage caused by cancer therapies

Australian researchers have identified a protein that could protect the kidneys from 'bystander' damage caused by cancer therapies.

25 Nov 2020

Septic shock and pneumonia triggered by SARS-CoV-2 could be treated by radiation-activated MSCs

This study, published in the journal Cells, is based on others (all of which employed experimental models) previously conducted by researchers at the Biomedical Research Centre of the University of Granada, the ‘López-Neyra’ Institute of Parasitology and Biomedicine, and the ‘Virgen de las Nieves’ University Hospital in Granada

23 Nov 2020

Researchers assess the risk of proton therapy for children with brain tumors

Adelaide is poised to open Australia's first proton therapy center in 2025, with children and young adults expected to be the main beneficiaries of more effective cancer treatment with fewer side effects.

12 Nov 2020

IU researcher awarded NCI grant to develop a drug for making radiation therapy more effective

An Indiana University Melvin and Bren Simon Comprehensive Cancer Center researcher has been awarded a five-year, $2.9 million grant from the National Cancer Institute to develop a drug that could make radiation therapy far more effective.

11 Nov 2020

Biodegradable 3D-printed esophageal stents for treating radiation esophagitis

Radiation esophagitis, characterized by the inflammation of the esophagus, is the most common acute adverse effect of radiation therapy that causes swallowing problems.

10 Nov 2020

High Throughput Identification and Quantification of Breast Cancer With NMR-Based Metabolomics

Breast cancer is the leading cause of cancer-related death among the female population globally, despite the ever-growing technology of early detection.

From Bruker BioSpin - NMR, EPR and Imaging 30 Oct 2020

High dose radiation therapy linked to shorter survival times in NSCLC patients

A genetic analysis of non-small cell lung cancer (NSCLC) patients on the phase III NRG Oncology RTOG 0617 clinical trial assessing radiation dose discovered that high dose radiation therapy is associated with shorter survival times among patients with a radiation-sensitive genotype in DNA repair pathway.

29 Oct 2020

Researchers report outcomes of salvage low dose RT brachytherapy after EBRT for prostate cancer

Researchers involved in the phase II NRG Oncology RTOG 0526 trial studying low dose rate (LDR) prostate brachytherapy (BT) following local recurrence (LR) after external beam radiotherapy (EBRT) for patients with low-to-intermediate risk prostate cancer reported late Grade 3 gastrointestinal and genitourinary adverse events (AEs) occurring in 14% of trial participants.

28 Oct 2020

Study finds persistence of racial disparities in treatment for common lung cancer

Lung cancer continues to be the most deadly solid cancer in the world, despite the fact that survival rates have been improving over the past decade.

28 Oct 2020

Ultramicroscopy helps visualize tumor tissues in three dimensions

After cancer surgery, the crucial question is: Are there possibly cancer cells left behind that can continue to grow, or has the entire tumor actually been removed? To find out, the tumor is examined by pathologists.

28 Oct 2020

High dose of radiation eliminates brain tumors in mice without key side effects

Treating cancer without debilitating side effects has long been the holy grail of oncologists, and researchers at the University of California, Irvine, and Switzerland's Lausanne University Hospital may have found it.

28 Oct 2020

Inflammasome may play a key role in triggering immune response to cancer

The inflammasome — a protein signaling network that is activated to rid the body of virus or bacteria-infected cells — may play an important role in triggering an immune response to cancer and causing an existing class of drugs to work better against cancers.

27 Oct 2020

Research details new strategy for overcoming treatment resistance by zeroing in on dendritic cells

Many of the most aggressive and hard-to-treat cancers are highly effective at blocking T cells, known as the foot soldiers of the immune system, from reaching and responding to tumors.

27 Oct 2020

Abbreviated MRI may be a valuable tool for supplemental screening of women with dense breasts

Beth Reisboard, 76, was relieved in 2018 when she received the results from her annual mammogram: "Negative." But her OB-GYN suggested she have a second screening. Reisboard has dense breasts, which means there are certain cancers that mammography may not be sensitive enough to detect.

27 Oct 2020

Phase II NRG Oncology trial evaluates two regimens for muscle-invasive bladder cancer

Bladder preservation with trimodality therapy can be a safe and effective alternative to cystectomy for selected patients with muscle-invasive bladder cancer.

27 Oct 2020

Radiation therapy before CART-BCMA appears to be a safe option for multiple myeloma patients

Administering radiation therapy to multiple myeloma patients waiting for CAR T cells to be manufactured was found to be safe and undisruptive to CAR T therapy, according to a new study from researchers in the Abramson Cancer Center at the University of Pennsylvania to be presented Tuesday, October 27, at the virtual American Society for Radiation Oncology Annual Meeting (Abstract #35562).

27 Oct 2020

Preliminary analysis of photon therapy treatment group 1 shows no significant differences between arms

A preliminary analysis of photon therapy treatment group 1 from the phase II NRG Oncology clinical trial NRG-BN001 indicates that there is no statistically significant overall survival (OS) or toxicity differences between dose-intensification radiation therapy (DI-RT) using intensity-modulated radiation therapy (IMRT) and standard-dose radiation therapy (SD-RT) with temozolomide treatments for patients with newly diagnosed glioblastoma (GBM).

27 Oct 2020

Metastasis-free survival is strongly linked to overall survival of men treated for prostate cancer

An analysis of the phase III NRG Oncology clinical trial RTOG 9601 on men receiving salvage radiotherapy (SRT) following prostatectomy for recurrent prostate cancer indicated that, while biochemical failure (BF) was not a strong surrogate endpoint to determine overall survival (OS), metastasis-free survival (MFS) was in this patient population.

27 Oct 2020

New approach can prevent aggressive operation in certain rectal cancer patients

A nonsurgical treatment option for rectal cancer that preserves quality of life is safe for carefully selected patients, according to a new study comparing it with the standard operation.

27 Oct 2020

Study analyzes link between clonal hematopoiesis and treatment-related blood cancer risk

In recent years, improvements in cancer therapy have led to a significant increase in cancer survivorship. Experts estimate that by 2022, the United States will have 18 million cancer survivors, but a subset of those survivors will have long-term health problems to be addressed.

27 Oct 2020

Radiation Therapy News and Research

Further Reading

Cell survival protein could protect kidneys from damage caused by cancer therapies

Septic shock and pneumonia triggered by SARS-CoV-2 could be treated by radiation-activated MSCs

Researchers assess the risk of proton therapy for children with brain tumors

IU researcher awarded NCI grant to develop a drug for making radiation therapy more effective

Biodegradable 3D-printed esophageal stents for treating radiation esophagitis

High Throughput Identification and Quantification of Breast Cancer With NMR-Based Metabolomics

High dose radiation therapy linked to shorter survival times in NSCLC patients

Researchers report outcomes of salvage low dose RT brachytherapy after EBRT for prostate cancer

Study finds persistence of racial disparities in treatment for common lung cancer

Ultramicroscopy helps visualize tumor tissues in three dimensions

High dose of radiation eliminates brain tumors in mice without key side effects

Inflammasome may play a key role in triggering immune response to cancer

Research details new strategy for overcoming treatment resistance by zeroing in on dendritic cells

Abbreviated MRI may be a valuable tool for supplemental screening of women with dense breasts

Phase II NRG Oncology trial evaluates two regimens for muscle-invasive bladder cancer

Radiation therapy before CART-BCMA appears to be a safe option for multiple myeloma patients

Preliminary analysis of photon therapy treatment group 1 shows no significant differences between arms

Metastasis-free survival is strongly linked to overall survival of men treated for prostate cancer

New approach can prevent aggressive operation in certain rectal cancer patients

Study analyzes link between clonal hematopoiesis and treatment-related blood cancer risk

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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