Genetic News and Research

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Alzheimer's disease appears to be highly heritable

In a large study of twins, Alzheimer's disease appears to be highly heritable and genetic factors may also influence timing of the disease, according to an article in the February Archives of General Psychiatry.

9 Feb 2006

New DNA-based cell adhesion strategy

A new technique in which single strands of synthetic DNA are used to firmly fasten biological cells to non-biological surfaces has been developed by researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California at Berkeley.

9 Feb 2006

Viruses can be forced to evolve in ways to benefit humans

Viruses and humans have evolved together over millions of years in a game of one-upmanship that, often as not, left humans sick or worse.

7 Feb 2006

Discovery of the molecular mechanism that inhibits HCV replication in vitro

Since its discovery several decades ago, the insidious human pathogen has stymied the quest for anti-viral therapies by refusing to reproduce in test tubes for more than a few hours or days, denying scientists an efficient virus production and infection system for experimental research.

7 Feb 2006

Microbia and DuPont collaborate to develop novel biomanufacturing process

Microbia, Inc. has announced the formation of a collaborative research and development program between DuPont Central Research & Development (CR&D) and Microbia's Precision Engineering business unit.

7 Feb 2006

Alzheimer disease has a genetic cause in up to 80 percent of cases

"Our finding confirms the higher estimates that have been suggested previously. The important thing is that no one has had this large a sample before," Gatz said, adding the size was 10 times that of any previous study.

7 Feb 2006

Common cardiac sodium channel variant associated with sudden infant death in African Americans

Steve A.N. Goldstein and colleagues from the Pritzker School of Medicine in Chicago have found that a specific mutation, called S1103Y, in a heart protein known as SCN5A is associated with a dramatic, 24-fold increased risk of sudden infant death syndrome (SIDS) in African American infants.

7 Feb 2006

Eosinophilic esophagitis gene discovery

Researchers at Cincinnati Children's Hospital Medical Center have discovered the first gene associated with eosinophilic esophagitis, one of a number of eosinophil-related diseases in which the body produces abnormally large amounts of white blood cells that can lead to allergy related illnesses.

7 Feb 2006

miRNA emerge as a class of gene regulators

Scientists have discovered that a wide variety of different cancers actually share something in common - a molecular "signature" made up of tiny bits of genetic material called microRNA (miRNA) that target key cancer genes and promote malignant growth.

7 Feb 2006

Link between dementia and cancer

By expressing a protein associated with Alzheimer's disease in the brain of the fruit fly, researchers have demonstrated an intriguing link between neuronal death and proteins previously associated with cancer.

7 Feb 2006

New insight into one of the fundamental features of evolution

By experimentally promoting rapid, small-scale evolution within a lab population of yeast, researchers have shed light on the kinds of genetic changes that may underlie the emergence of new species.

7 Feb 2006

Abraham Lincoln may have suffered from movement disorder

Researchers at Johns Hopkins and the University of Minnesota have discovered a gene mutation in the descendants of Abraham Lincoln's grandparents that suggests the Civil War president himself might have also suffered from a disease that destroys nerve cells in the cerebellum-- the part of the brain that controls movement.

7 Feb 2006

Research sheds light on origins of "junk" DNA

In experiments with transgenic mice, University of Pennsylvania School of Medicine researchers discovered the remaining steps in the complicated process of how the largest class of jumping genes replicates and inserts themselves within the human genome.

7 Feb 2006

Rotavirus vaccine will protect children against a major killer worldwide

The Food and Drug Administration (FDA) has announced the licensing of a new vaccine against a disease responsible for tens of thousands of hospitalizations in the United States and hundreds of thousands of deaths around the world each year.

7 Feb 2006

Intracellular observation of RNA metabolism will help identify disease-associated RNAs

For the first time, researchers can now peer inside intact cells to not only identify RNA-binding proteins, but also observe-in real-time-the intricate activities of these special molecules that make them key players in managing some of the cell's most basic functions.

7 Feb 2006

Black men least likely to get prostate cancer screening even during peak ages of risk

The men most at risk for aggressive prostate cancer - black men with a family history - are the least likely to get screening even during peak ages of risk, researchers say.

5 Feb 2006

Study looks at placebo effect

The debate about the existence of a placebo effect has heated up over the past year as more and more lab experiments are detecting immediate physiological responses to placebos.

2 Feb 2006

60 new genes controlled by regulatory sequences

Researchers worldwide are seeking to define ancient sections of our genetic code that may soon be as important to medical science as genes.

2 Feb 2006

Are dancers genetically different than the rest of us?

What makes dancers different than the rest of us? Genetic variants, says a researcher at the Hebrew University of Jerusalem.

2 Feb 2006

Chinese medicine shows promise as treatment for sperm genetic abnormalities

Bioscientists from the University of Kent have called for clinical trials to further investigate how traditional Chinese medicine (TCM) may have a positive effect on sperm genetic abnormalities, and thereby influence the success rate of male infertility treatment.

2 Feb 2006